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RPB2 Rpb2p

This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq, Jul 2008] (from NCBI)
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Top mentioned proteins: POLYMERASE, Rpb1, NOV, CAN, Nuc
Papers on RPB2
DNA barcoding, MALDI-TOF, and AFLP data support Fusarium ficicrescens as a distinct species within the Fusarium fujikuroi species complex.
de Hoog et al., Utrecht, Netherlands. In Fungal Biol, Feb 2016
Multilocus analyses were based on translation elongation factor 1α (TEF1), RNA polymerase subunit (RPB2) and beta-tubulin (BT2) and proved F. ficicrescens as a member of the FFSC.
Evaluation of two novel barcodes for species recognition of opportunistic pathogens in Fusarium.
Levesque et al., Utrecht, Netherlands. In Fungal Biol, Feb 2016
Species determination is best made with the combined phylogeny of protein-coding genes such as elongation factor (TEF1), RNA polymerase (RPB2) and the partial β-tubulin (BT2) gene.
Identification, pathogenicity and abundance of Paracremonium pembeum sp. nov. and Graphium euwallaceae sp. nov.-two newly discovered mycangial associates of the polyphagous shot hole borer (Euwallacea sp.) in California.
Eskalen et al., Riverside, United States. In Mycologia, Feb 2016
Fungi were identified based on micromorphology and phylogenetic analyses of the combined internal transcribed spacer region (nuc rDNA ITS1- 5.8S-ITS2 [ITS barcode]), elongation factor (EF 1-α), small subunit (18S rDNA) sequences for Graphium spp., ITS, EF 1-α, calmodulin (cmdA), large subunit of the ATP citrate lyase (acl1), β-tubulin (tub2), RNA polymerase II second largest subunit (rpb2) and large subunit (28S rDNA) sequences for Paracremonium spp.
Systematics of the ectomycorrhizal genus Lactarius in the Rocky Mountain alpine zone.
Osmundson et al., La Crosse, United States. In Mycologia, Feb 2016
(ITS barcode) and the second largest subunit of the RNA polymerase II gene (RPB2) partial sequences in conjunction with detailed morphological examination confirm at least six species occurring above treeline.
Botrytis californica, a new cryptic species in the B. cinerea species complex causing gray mold in blueberries and table grapes in California.
Xiao et al., Davis, United States. In Mycologia, Feb 2016
Phylogenetic analysis with the three partial gene sequences encoding glyceraldehyde-3-phosate dehydrogenase (G3PDH), heat-shock protein 60 (HSP60) and DNA-dependent RNA polymerase subunit II (RPB2) supported the proposal of a new Botrytis species, B. californica, which is closely related genetically to B. cinerea, B. pseudocinerea and B. sinoviticola, all known as causal agents of gray mold of grapes.
Ancestral state reconstruction infers phytopathogenic origins of sooty blotch and flyspeck fungi on apple.
Gleason et al., Kuala Selangor, Malaysia. In Mycologia, Feb 2016
830 bp from near the 5' end) and the second largest subunit of RNA polymerase II (RPB2).
Lactifluus volemus in Europe: Three species in one - Revealed by a multilocus genealogical approach, Bayesian species delimitation and morphology.
Verbeken et al., Gent, Belgium. In Fungal Biol, Jan 2016
This study provides morphological and molecular evidence (from nuclear ITS, LSU, and rpb2 DNA sequences) for three previously unrecognized species within the morphospecies Lactifluus volemus from Europe.
A Re-examination of the Taxonomic Status of Embellisia astragali.
Creamer et al., Lanzhou, China. In Curr Microbiol, Jan 2016
A phylogenetic tree developed based on the sequences of 3 loci (GPD, RPB2, and TEF-1) strongly supported the placement of E. astragali in Alternaria sect.
Description of a taxonomically undefined Sclerotiniaceae strain from withered rotten-grapes.
Zapparoli et al., Verona, Italy. In Antonie Van Leeuwenhoek, Dec 2015
Phylogenetic analysis of partial sequences of glyceraldehyde 3-phosphate dehydrogenase (G3PDH), heat shock protein 60 (HSP60) and DNA-directed RNA polymerase II subunit (RPB2), revealed that strain C10 is distantly related to Amphobotrys and Botrytis.
From one to six: unrecognized species diversity in the genus Acantholichen (lichenized Basidiomycota: Hygrophoraceae).
Lawrey et al., Chicago, United States. In Mycologia, Dec 2015
region and 28S of the nuc rDNA and RPB2 sequences, revealed a much more diverse and widespread species assemblage.
Three new species of Physalacria from China, with a key to the Asian taxa.
Yang et al., Kunming, China. In Mycologia, Dec 2015
Placements of these species were corroborated based on morphological observations and molecular evidence from partial sequences of the nuc rDNA internal transcribed spacer regions (ITS) and the 28S D1-D3 region, and genes for translation elongation factor 1-α (tef1α) and the second largest subunit of RNA polymerase II (rpb2).
Variation in Type A Trichothecene Production and Trichothecene Biosynthetic Genes in Fusarium goolgardi from Natural Ecosystems of Australia.
Liew et al., Sydney, Australia. In Toxins (basel), 2014
In the phylogenies inferred from DNA sequences of genes encoding the RNA polymerase II largest (RPB1) and second largest (RPB2) subunits as well as the trichothecene biosynthetic genes (TRI), F. goolgardi isolates were resolved as a monophyletic clade, distinct from other type A trichothecene-producing species.
Crucial role of a dicarboxylic motif in the catalytic center of yeast RNA polymerases.
Thuriaux et al., Gif-sur-Yvette, France. In Curr Genet, 2011
study examined the properties of the corresponding RNAPII (Rpb2-832GYNQED837) and RNAPIII (Rpc128-764GYDIED769) loops by a local mutagenesis of their invariant carboxyl acids
Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation.
Adelman et al., United States. In Biochim Biophys Acta, 2011
Studies indicate transcription of many genes, is regulated after the initiation step, by pausing of RNA polymerase II during elongation through the promoter-proximal region.
Phosphorylation of the RNA polymerase II C-terminal domain by TFIIH kinase is not essential for transcription of Saccharomyces cerevisiae genome.
Lee et al., Suwŏn, South Korea. In Proc Natl Acad Sci U S A, 2009
Study points strongly toward a minor role of TFIIH kinase in Pol II transcription, and a more significant role in mRNA capping in budding yeast.
The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif.
Tsai et al., Columbus, United States. In Nat Struct Mol Biol, 2008
ARID is required for RBP2 demethylase activity in cells and that DNA recognition is essential to regulate transcription
Hepatitis delta antigen binds to the clamp of RNA polymerase II and affects transcriptional fidelity.
Handa et al., Yokohama, Japan. In Genes Cells, 2007
By reducing transcriptional fidelity in terms of not only discrimination of incoming nucleotides but also recognition of templates, HDAg may facilitate the unusual RNA-dependent RNA synthesis by Pol II.
A phylogenetic overview of the Agaricomycotina.
Hibbett, Worcester, United States. In Mycologia, 2006
Recent phylogenetic analyses by P. Matheny and colleagues combining nuclear rRNA genes with the protein-coding genes rpb1, rpb2 and tef1 support the division of Agaricomycotina into Tremellomycetes, Dacrymycetes and Agaricomycetes.
Phylogeny of filamentous ascomycetes.
Lumbsch, Essen, Germany. In Naturwissenschaften, 2000
Most studies employed sequences of the SSU rRNA gene, but recently data from additional genes (RPB2, LSU rRNA) have become available.
A suppressor of a HIS4 transcriptional defect encodes a protein with homology to the catalytic subunit of protein phosphatases.
Fink et al., Cambridge, United States. In Cell, 1989
Two of these suppressors, SIT1 and SIT2, are encoded by RPB1 and RPB2, the genes for the two largest subunits of RNA polymerase II.
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