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PRP3 pre-mRNA processing factor 3 homolog

RP-18
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, SIMPLE, fibrillin-1, OUT, CAN
Papers using RP-18 antibodies
Leukotriene B(4) BLT receptor signaling regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of Ras/Raf/ERK/p42 AUF1 pathway
Supplier
van Weeren Paul René et al., In Arthritis Research & Therapy, 2009
... Solid-phase extraction columns (LiChrolut RP-18; 100-mg column bed) were purchased from Merck (Darmstadt, Germany).
Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors
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Rathbone Michel P. et al., In Purinergic Signalling, 2006
... Separation was carried out with a reverse-phase analytical column (LiChroCART 125-4 LiChrospher 100 RP-18 5 μm, Merck, Darmstadt, Germany) and the ...
Identification and pharmacological characterization of a novel human melanin-concentrating hormone receptor, MCH-R2
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Wadsak W. et al., In Applied Radiation and Isotopes, 2000
... 1.07734) or LiChroprep RP-18 silica gel (40–63 μm, 1.13900) from Merck was used ...
The organisation of the Golgi apparatus
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Wieland Felix T. et al., In The Journal of Cell Biology, 1997
... Silica gel 60 (40–63 μm) and RP-18 silica gel (40–63 μm) were obtained from Merck.
Mechanism of Mitotic Block and Inhibition of Cell-Proliferation by Taxol at Low Concentrations
Supplier
Saudou Frédéric, In PLoS ONE, 1992
... The reactions course was followed using silicagel and RP18-silicagel TLC plates (Merck, Darmstadt, Germany).
Papers on RP-18
Selective solid-phase extraction using molecularly imprinted polymer as a sorbent for the analysis of fenarimol in food samples.
New
Roy et al., Lucknow, India. In Food Chem, Jun 2016
The validated method of molecularly imprinted solid-phase extraction (MISPE) cartridge was successfully applied to the food matrices and compared with commercial sorbent (RP18 and Oasis HLB).
Development of RP UPLC-TOF/MS, stability indicating method for omeprazole and its related substances by applying two level factorial design; and identification and synthesis of non-pharmacopoeial impurities.
New
Bhosale et al., Hyderābād, India. In J Pharm Biomed Anal, Feb 2016
Impurity-I (1), OMP related compound-I (11) and OMP 4-chloro analog (12) was achieved in a single method on Acquity BEH shield RP18 100×2.1mm,
On-line automated evaluation of lipid nanoparticles transdermal permeation using Franz diffusion cell and low-pressure chromatography.
New
Reis et al., Porto, Portugal. In Talanta, Feb 2016
Under the selected conditions (monolithic column Chromolith® RP-18 15mm×4.6mm
Anti-inflammatory sesquiterpenes from Costus speciosus rhizomes.
New
Esmat et al., Jiddah, Saudi Arabia. In J Ethnopharmacol, Jan 2016
MATERIALS AND METHODS: The n-hexane-CHCl3 soluble fraction of the MeOH extract of C. speciosus rhizomes has been subjected to a repeated column chromatography, including normal silica gel and RP-18 column to give eight compounds.
Ultra-performance liquid chromatography-tandem mass spectrometric assay for the simultaneous determination of brucine, strychnine and brucine N-oxide in rat plasma: application to a pharmacokinetic study.
New
Chen et al., Nanjing, China. In Biomed Chromatogr, Dec 2015
The analytes were separated on a Purospher® STAR RP-18 UHPLC column (2 µm, 2.1 mm × 100 mm) by gradient elution using a mobile phase composed of methanol and water (containing 0.1 % formic acid) at a flow rate of 0.3 mL/min.
Newest strategies in the search for bioactive saponins from the tropical plant biodiversity.
New
Lacaille-Dubois, Dijon, France. In Curr Drug Deliv, Dec 2015
Then, a multistep purification procedure was achieved by flash chromatography, vacuum liquid chromatography, low, medium- and high-pressure liquid chromatography on silica gel and reversed-phase silica gel RP-18 (VLC, LPLC, MPLC, HPLC).
Quantitative analysis of biomarker rutin in different species of genus Ficus by validated NP and RP-HPTLC methods.
New
Hussain et al., Riyadh, Saudi Arabia. In Pak J Pharm Sci, Nov 2015
Method II was carried out on silica gel 60F254 RP-18 plates using mobile phase ACN: H2O (4:6 v/v).
[Chemical Constituents of Eucommia ulmoides in Guizhou Province].
New
Zhang et al., In Zhong Yao Cai, May 2015
METHODS: Silica gel, Sephadex LH-20, RP-18, MCI and semi-preparative HPLC were used to study the chemical constituents of Eucommia ulmoides, and the chemical structures were elucidated by application of spectral data.
[Chemical Constitutes from Root of Artocarpus styracifolius].
New
Yuan et al., In Zhong Yao Cai, May 2015
METHODS: Tne constituents were isolated from the root of Artocarpus styracifolius by column chromatography over silica gel, RP-18 silica gel, MCI GEL CHP-20P, macroporous resin HP-20, Sephadex LH-20, Toyopearl HW-40C and by preparative HPLC.
[Study on Flavonoids in Buddleja lindleyana Fruits].
New
Zhang et al., In Zhong Yao Cai, Apr 2015
METHODS: The compounds were separated by repeated silica gel, RP-18 and Sephadex LH-20.
PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.
GeneRIF
Rivolta et al., Toronto, Canada. In Hum Mol Genet, 2011
RP-PRPF defects affect the stoichiometry of spliceosomal small nuclear RNAs. Mutant PRPF3 proteins stably associated with tri-snRNPs.
Variable phenotypic expressivity in a Swiss family with autosomal dominant retinitis pigmentosa due to a T494M mutation in the PRPF3 gene.
GeneRIF
Munier et al., Lausanne, Switzerland. In Mol Vis, 2009
A mutation in the PRPF3 gene is rare compared to other genes causing autosomal dominant retinitis pigmentosa.
Contribution of the individual subunits of protein kinase CK2 and of hPrp3p to the splicing process.
GeneRIF
Montenarh et al., Homburg, Germany. In Mol Cell Biochem, 2008
These data support the notion about individual roles for CK2alpha and CK2alpha' in the splicing process.
EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas.
GeneRIF
Borlak et al., Hannover, Germany. In Gastroenterology, 2008
TASP1, EPS15R, and PRPF3 expression were significantly induced in HCCs of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha
Splicing factor SPF30 bridges an interaction between the prespliceosome protein U2AF35 and tri-small nuclear ribonucleoprotein protein hPrp3.
GeneRIF
Jurica et al., Santa Cruz, United States. In J Biol Chem, 2008
U2AF35 and hPrp3 interactions with SPF30 can occur simultaneously, thereby potentially linking 3' splice site recognition with tri-small nuclear ribonucleoprotein addition
Simultaneous enantiomer determination of 20 (R)- and 20 (S)-ginsenoside-Rg2 in rat plasma after intravenous administration using HPLC method.
Review
Tian et al., Beijing, China. In J Chromatogr B Analyt Technol Biomed Life Sci, 2007
The enantiomeric separation and determination were successfully achieved using a Diamonsil ODS C18 reversed-phase column (5 microm, 250 mm x 4.6 mm) with an RP18 (5 microm) guard column and a mobile phase of MeOH-aq.
Cysteine and indole derivatives as markers for malignant melanoma.
Review
Arndt et al., Hamburg, Germany. In J Chromatogr B Biomed Sci Appl, 2001
For HPLC, standard RP18 separating columns and usual compositions of eluents were applied.
[Reversed-phase high-performance liquid chromatograph--application to serum aluminium monitoring].
Review
Kaneko et al., In Nihon Rinsho, 1996
The A1 chelate with 2,2'-dihydroxyazobenzene is efficiently chromatographed on a LiChroCART RP-18 column using an aqueous methanol eluent (63.6 wt%) containing tetrabutylammonium bromide as an ion-pair agent.
Determination of biological equivalence of two atenolol preparations.
Review
Vrhovac et al., Zagreb, Croatia. In Int J Clin Pharmacol Ther Toxicol, 1987
Chromatography was performed on RP-18 column (10 mu) with mobile phase of 0.015 mol/l KH2PO4/acetonitrile 70:30.
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