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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Zinc finger and BTB domain containing 32

ROG, repressor of GATA, FAZF, TZFP
Top mentioned proteins: GATA3, TH2, PLZF, ACID, IL-4
Papers on ROG
Low CSC marker expression and low hypoxia identify good prognosis subgroups in HPV(-)HNSCC after postoperative radiochemotherapy: a multicenter study of the DKTK-ROG.
Krause et al., Dresden, Germany. In Clin Cancer Res, Feb 2016
PURPOSE: To investigate the impact of hypoxia-induced gene expression and cancer stem cell (CSC) marker expression on outcome of postoperative cisplatin-based radiochemotherapy (PORT-C) in patients with locally advanced head and neck squamous cell carcinoma (HNSCC).
CD8+ tumour-infiltrating lymphocytes in relation to HPV status and clinical outcome in patients with head and neck cancer after postoperative chemoradiotherapy: A multicentre study of the German cancer consortium radiation oncology group (DKTK-ROG).
Fokas et al., Frankfurt am Main, Germany. In Int J Cancer, Feb 2016
Further validation of the prognostic value of CD8+ TILs as a biomarker and its role in the immune response in SCCHN patients after adjuvant chemoradiotherapy is warranted and will be performed in the prospective DKTK-ROG study.
Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells.
Liaudet-Coopman et al., Montpellier, France. In Oncotarget, Oct 2015
We identified TRPS1 (tricho-rhino-phalangeal-syndrome 1), a repressor of GATA-mediated transcription, and BAT3 (Scythe/BAG6), a nucleo-cytoplasmic shuttling chaperone protein, as new Cath-D-interacting nuclear proteins.
Protective effect of platycodin D on liver injury in alloxan-induced diabetic mice via regulation of Treg/Th17 balance.
Yan et al., Nanjing, China. In Int Immunopharmacol, Jun 2015
Fifty mice were divided into five groups randomly: control group, model group, rosiglitazone (ROG, 10 mg/kg) group, PLD (50 mg/kg) group, and PLD (100 mg/kg) group.
HPV16 DNA status is a strong prognosticator of loco-regional control after postoperative radiochemotherapy of locally advanced oropharyngeal carcinoma: results from a multicentre explorative study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).
DKTK-ROG et al., Dresden, Germany. In Radiother Oncol, 2014
OBJECTIVE: To investigate the impact of HPV status in patients with locally advanced head and neck squamous cell carcinoma (HNSCC), who received surgery and cisplatin-based postoperative radiochemotherapy.
The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection.
Sun et al., New York City, United States. In Nat Immunol, 2014
Here we demonstrate that the BTB-ZF transcription factor Zbtb32 (also known as ROG, FAZF, TZFP and PLZP) was essential for the proliferative burst and protective capacity of virus-specific NK cells.
Poly(ADP-ribose) polymerase-1 and its cleavage products differentially modulate cellular protection through NF-kappaB-dependent signaling.
Hallenbeck et al., In Biochim Biophys Acta, 2014
Compared to WT (PARP-1WT), the expression of an uncleavable PARP-1 (PARP-1(UNCL)) or of PARP-1(24) conferred protection from oxygen/glucose deprivation (OGD) or OGD/restoration of oxygen and glucose (ROG) damage in vitro, whereas expression of PARP-1(89) was cytotoxic.
[Effect of ginsenoside Rb1 in ameliorating insulin resistance and ectopic fat deposition in obese mice induced by high fat diet].
Zhao et al., In Zhongguo Zhong Yao Za Zhi, 2013
Obese male C57/L mice induced by high fat diet were randomly divided into the diet-induced obesity group (DIO group), the ginsenoside Rb1 group (Rb1 group) and the rosiglitazone group (Rog group), and continuously fed with high fat diet.
Rosiglitazone alleviates injury in rats with adenine‑induced chronic kidney disease.
Yu et al., Guangzhou, China. In Mol Med Report, 2013
Rosiglitazone (ROG) has been shown to exert beneficial effects on glycemic control and renal protection.
Tzfp represses the androgen receptor in mouse testis.
Klungland et al., Oslo, Norway. In Plos One, 2012
The testis zinc finger protein (Tzfp), also known as Repressor of GATA, belongs to the BTB/POZ zinc finger family of transcription factors and is thought to play a role in spermatogenesis due to its remarkably high expression in testis.
Alkbh1 and Tzfp repress a non-repeat piRNA cluster in pachytene spermatocytes.
Klungland et al., Oslo, Norway. In Nucleic Acids Res, 2012
The 1082B precursor transcript and its 788 unique piRNAs are repressed by the Alkbh1 dioxygenase and the testis-specific transcription repressor Tzfp.
Repressor of GATA negatively regulates murine contact hypersensitivity through the inhibition of type-2 allergic responses.
Nakayama et al., Chiba, Japan. In Clin Immunol, 2011
Rog plays an inhibitory role in allergic inflammation.
Structure and DNA binding characteristics of the three-Cys(2)His(2) domain of mouse testis zinc finger protein.
Chen et al., Taipei, Taiwan. In Proteins, 2010
structure of zinc-finger domains; kinetics of DNA binding; DNA sequence-specific binding & nonsequence-specific binding occur simultaneously
Insights into strand exchange in BTB domain dimers from the crystal structures of FAZF and Miz1.
Privé et al., Toronto, Canada. In J Mol Biol, 2010
confirmed that the promyelocytic leukemia zinc finger (PLZF) BTB dimer is strand exchanged in solution, while the FAZF BTB dimer is not
Human endogenous retrovirus protein Rec interacts with the testicular zinc-finger protein and androgen receptor.
Mueller-Lantzsch et al., Homburg, Germany. In J Gen Virol, 2010
Here, it was shown that human endogenous retrovirus Rec can form a trimeric complex with TZFP and AR, and can relieve the TZFP-mediated repression of AR-induced transactivation.
Repressor of GATA regulates TH2-driven allergic airway inflammation and airway hyperresponsiveness.
Nakayama et al., Chiba, Japan. In J Allergy Clin Immunol, 2008
results indicate that ROG regulates allergic airway inflammation and airway hyperresponsiveness in a negative manner
POZ for effect--POZ-ZF transcription factors in cancer and development.
Daniel et al., Hamilton, Canada. In Trends Cell Biol, 2006
Consequently, dysfunction of vertebrate POZ-ZF proteins, such as promyelocytic leukemia zinc finger (PLZF), B cell lymphoma 6 (Bcl-6), hypermethylated in cancer 1 (HIC-1), Kaiso, ZBTB7 and Fanconi anemia zinc finger (FAZF), has been linked directly or indirectly to tumorigenesis and developmental disorders.
CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA.
Nakayama et al., Chiba, Japan. In Immunity, 2003
ROG may confer CD8 T cell-specific repression of histone hyperacetylation and activation of the IL-4 gene locus.
GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation.
Alberola-Ila et al., Pasadena, United States. In Immunity, 2003
Conversely, expression of the GATA-3 antagonist ROG or of a GATA-3 siRNA hairpin markedly enhances development of CD8 SP cells and reduces CD4 SP development.
ROG, repressor of GATA, regulates the expression of cytokine genes.
Ho et al., Boston, United States. In Immunity, 2000
Here, we report the molecular cloning of a GATA-3 interacting protein, repressor of GATA (ROG).
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