Slit2-Robo signaling in inflammation and kidney injury.
Vellore, India. In Pediatr Nephrol, Apr 2015
In this review, we summarize recent findings demonstrating that the neuronal guidance cues, Slit and Roundabout (Robo), prevent the migration of multiple leukocyte subsets towards diverse inflammatory chemoattractants, and have potent anti-platelet functions in vitro and in vivo.
In Adv Neurobiol, 2013
Roundabout receptors (Robo) and their Slit ligands were discovered in the 1990s and found to be key players in axon guidance.