Close encounters of the RNF8th kind: when chromatin meets DNA repair.
Leiden, Netherlands. In Curr Opin Cell Biol, 2012
Emerging evidence suggests that the histone ubiquitin ligases RNF8/RNF168 act in concert with ATP-dependent chromatin remodelling enzymes to orchestrate the signalling and repair of DNA lesions in specific chromatin topologies.
Fusing telomeres with RNF8.
Amsterdam, Netherlands. In Nucleus, 2012
DNA repair activities at DNA double-strand breaks (DSBs) are under control of regulatory ubiquitylation events governed by the RNF8 and RNF168 ubiquitin-ligases.