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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

RIO2 Rio2p

Rio2, Rio2p
Top mentioned proteins: bystin, CRM1, NOB1, CKI, CAN
Papers on Rio2
Discovery of selective RIO2 kinase small molecule ligand.
New
Vieth et al., Indianapolis, United States. In Biochim Biophys Acta, Oct 2015
The RIO2 kinase affinity of diphenpyramide was discovered by serendipity while profiling of 13 marketed drugs on a large 456 kinase assay panel.
CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.
Kutay et al., Zürich, Switzerland. In J Cell Sci, 2014
Inhibition or co-depletion of CK1δ and CK1ε results in failure to recycle a series of trans-acting factors including ENP1/BYSL, LTV1, RRP12, DIM2/PNO1, RIO2 and NOB1 from pre-40S particles after nuclear export.
Molecular and structural insight into plasmodium falciparum RIO2 kinase.
Bal et al., Rānchī, India. In J Mol Model, 2013
Among approximately 65 kinases of the malarial genome, RIO2 (right open reading frame) kinase belonging to the atypical class of kinase is unique because along with a kinase domain, it has a highly conserved N-terminal winged helix (wHTH) domain.
Phosphorylation of right open reading frame 2 (Rio2) protein kinase by polo-like kinase 1 regulates mitotic progression.
GeneRIF
Ye et al., Beijing, China. In J Biol Chem, 2011
Plk1-mediated phosphorylation of Rio2 regulates metaphase-anaphase transition during mitotic progression.
Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2.
GeneRIF
Kutay et al., Zürich, Switzerland. In J Cell Biol, 2009
Results show that the protein kinase human Rio2 (hRio2) is part of a late 40S preribosomal particle in human cells.
Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells.
Gleizes et al., Toulouse, France. In Embo J, 2005
Here, we show that pre-40S particles exported to the cytoplasm in HeLa cells contain 18S rRNA extended at the 3' end with 20-30 nucleotides of the internal transcribed spacer 1. Maturation of this pre-18S rRNA (which we named 18S-E) involves a cytoplasmic protein, the human homolog of the yeast kinase Rio2p, and appears to be required for the translation competence of the 40S subunit.
The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast.
Gleizes et al., Toulouse, France. In Embo J, 2004
Most pre-40S specific factors are correctly associated with the intermediate particles accumulating in the nucleus upon Rps15p depletion, except the late-binding proteins Tsr1p and Rio2p.
Rio2p, an evolutionarily conserved, low abundant protein kinase essential for processing of 20 S Pre-rRNA in Saccharomyces cerevisiae.
Raué et al., Amsterdam, Netherlands. In J Biol Chem, 2003
Failure to deplete Rio2p in cells containing a GAL-rio2 gene and direct analysis of Rio2p levels by Western blotting indicated the protein to be low abundant.
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.
Hurt et al., Heidelberg, Germany. In Embo J, 2003
Rio2p and Nob1p) are found mainly on late cytoplasmic pre-40S subunits.
Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae.
Caizergues-Ferrer et al., Toulouse, France. In Mol Cell Biol, 2003
By BLAST analysis, we identified the product of a previously uncharacterized essential gene, YNL207W/RIO2, called Rio2p, that shares 43% sequence similarity with Rrp10p/Rio1p.
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