The tRNA Elbow in Structure, Recognition and Evolution.
Bethesda, United States. In Life (basel), Dec 2015
At least three classes of non-coding RNAs, namely 23S rRNA, ribonuclease P, and the T-box riboswitches, recognize the tRNA elbow employing an identical structural motif consisting of two interdigitated T-loops.
Structural studies of RNase P.
Evanston, United States. In Annu Rev Biophys, 2012
Ribonuclease P (RNase P) is one of the first ribozymes discovered and it is found in all phylogenetic groups.
Inhibition of gene expression by RNase P.
Tromsø, Norway. In N Biotechnol, 2010
Here we discuss methodologies for inhibition of target RNAs based on the cleavage activity of the essential enzyme, Ribonuclease P (RNase P).
Trials, travails and triumphs: an account of RNA catalysis in RNase P.
Madison, United States. In J Mol Biol, 2010
Last December marked the 20th anniversary of the Nobel Prize in Chemistry to Sidney Altman and Thomas Cech for their discovery of RNA catalysts in bacterial ribonuclease P (an enzyme catalyzing 5' maturation of tRNAs) and a self-splicing rRNA of Tetrahymena, respectively.
A protein-only RNase P in human mitochondria.
Ann Arbor, United States. In Cell, 2008
In bacteria, archaea, and the eukaryote nucleus, the endonuclease ribonuclease P (RNase P) is composed of a catalytic RNA that is assisted by protein subunits.
Life without RNase P.
New Haven, United States. In Nature, 2008
The universality of ribonuclease P (RNase P), the ribonucleoprotein essential for transfer RNA (tRNA) 5' maturation, is challenged in the archaeon Nanoarchaeum equitans.