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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Interferon-induced protein with tetratricopeptide repeats 5

RI58, IFIT5
Top mentioned proteins: ACID, CAN, RIG-G, ISG54, RIG-I
Papers on RI58
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
New
Wang et al., Wuhan, China. In Cell Signal, Dec 2015
Here we demonstrate that IFIT5, one of the interferon induced tetratricopeptide repeat family members, enhances IKK phosphorylation and NF-κB activation through interacting with TAK1 and IKK.
Inferring genome-wide functional modulatory network: a case study on NF-κB/RelA transcription factor.
New
Kudlicki et al., Galveston, United States. In J Comput Biol, Apr 2015
The modulatory networks of NF-κB/RelA in the context epithelial-mesenchymal transition (EMT) and burn injury have different modulators, including those involved in extracellular matrix (FBN1), cytoskeletal regulation (ACTN1), and metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long intergenic nonprotein coding RNA, and tumor suppression (FOXP1) for EMT, and TXNIP, GAPDH, PKM2, IFIT5, LDHA, NID1, and TPP1 for burn injury.
Comparative analysis of selected innate immune-related genes following infection of immortal DF-1 cells with highly pathogenic (H5N1) and low pathogenic (H9N2) avian influenza viruses.
New
Song et al., Jinan, China. In Virus Genes, Apr 2015
To address this hypothesis, expression of a panel of innate immune-related genes including IFN-α, IFN-β, Mx1, OASL, ISG12, IFIT5, IRF7, USP18, SST, and KHSRP in immortal DF-1 cells following H5N1 and H9N2 infection was analyzed and compared by real-time quantitative RT-PCR.
Differential Expression Profile of Chicken Embryo Fibroblast DF-1 Cells Infected with Cell-Adapted Infectious Bursal Disease Virus.
Leung et al., Hong Kong, Hong Kong. In Plos One, 2014
In addition to the reported regulatory factors including EIF2AK2, MX, OAS*A, GBP7 and IFIT, IBDV infection also triggered a IFIT5-IRF1/3-RSAD5 pathway in the DF-1 cells which potentially restricted the viral replication cycle in the early infection stage.
Identification and expression analysis of the interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) gene in duck (Anas platyrhynchos domesticus).
Chen et al., Yangzhou, China. In Plos One, 2014
Several members of this family, including IFIT1, IFIT2, IFIT3 and IFIT5, have been heavily studied in mammals.
Early bovine embryos regulate oviduct epithelial cell gene expression during in vitro co-culture.
Locatelli et al., France. In Anim Reprod Sci, 2014
Of these 34 genes, IFI6, ISG15, MX1, IFI27, IFI44, RSAD2, IFITM1, EPSTI1, USP18, IFIT5, and STAT1 expression increased to the greatest extent due to the presence of embryos with a major impact on antiviral and immune response.
Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5.
Collins et al., Berkeley, United States. In Proc Natl Acad Sci U S A, 2014
Here we show that human IFIT5 has comparable affinity for RNAs with diverse phosphate-containing 5'-ends, excluding the higher eukaryotic mRNA cap.
Protection of Atlantic salmon against virus infection by intramuscular injection of IFNc expression plasmid.
Robertsen et al., Tromsø, Norway. In Vaccine, 2014
All three IFN plasmids induced expression of antiviral genes (Mx, Viperin, ISG15 and IFIT5) at the muscle injection site while the control plasmid had little effect.
Human dendritic cells exhibit a pronounced type I IFN signature following Leishmania major infection that is required for IL-12 induction.
McDowell et al., India. In J Immunol, 2014
Our data revealed that L. major, but not L. donovani, induces expression of IRF2, IRF7, and IFIT5, implicating the regulation of type I IFN-associated signaling pathways as mediating factors toward the production of IL-12.
Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5'-terminal regions of cap0-, cap1- and 5'ppp- mRNAs.
Pestova et al., United States. In Nucleic Acids Res, 2014
The 5'-terminal regions of 5'ppp-mRNAs were recognized by IFIT5 (K1/2,app ∼400 nM).
Gene expression in the chicken caecum in response to infections with non-typhoid Salmonella.
Review
Kyrova et al., Brno, Czech Republic. In Vet Res, 2013
Additional highly inducible genes in the caecum following S. Enteritidis infection include immune responsive gene 1 (IRG1), serum amyloid A (SAA), extracellular fatty acid binding protein (ExFABP), serine protease inhibitor (SERPINB10), trappin 6-like (TRAP6), calprotectin (MRP126), mitochondrial ES1 protein homolog (ES1), interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), avidin (AVD) and transglutaminase 4 (TGM4).
Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Impact
Nagar et al., Montréal, Canada. In Nature, 2013
Here we report crystal structures of human IFIT5, its complex with PPP-RNAs, and an amino-terminal fragment of IFIT1.
Protective roles of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) in dengue virus infection of human lung epithelial cells.
Lai et al., Taipei, Taiwan. In Plos One, 2012
The results demonstrated that DV infection induced expression of several IFITs, including IFIT1, IFIT2, IFIT3, and IFIT5 in A549 cells.
Interferon induced IFIT family genes in host antiviral defense.
Review
Jiang et al., Pullman, United States. In Int J Biol Sci, 2012
Most mammals have IFIT1, IFIT2, IFIT3 and IFIT5; however, bird, marsupial, frog and fish have only IFIT5.
The ISG56/IFIT1 gene family.
Review
Sen et al., Cleveland, United States. In J Interferon Cytokine Res, 2011
The ISG56/IFIT1 family of genes is clustered on human chromosome 10 and is comprised of 4 members, ISG56/IFIT1, ISG54/IFIT2, ISG60/IFIT3, and ISG58/IFIT5, whose homologs are evolutionarily conserved from mammals to amphibians.
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