Inhibitory effects of Arhgap6 on cervical carcinoma cells.
Shanghai, China. In Tumour Biol, Jan 2016
UNASSIGNED: Ras homology GTPase activation protein 6 (Arhgap6), as a member of the rhoGAP family of proteins, performs vital functions on the regulation of actin polymerization at the plasma membrane during several cellular processes.
Rho regulation: DLC proteins in space and time.
Stuttgart, Germany. In Cell Signal, Aug 2015
In this review we will focus on the Deleted in Liver Cancer (DLC) family of RhoGAP proteins and summarize the evidence gathered over the past years revealing their different subcellular localizations that might account for isoform-specific functions.
Molecular physiology of the tensin brotherhood of integrin adaptor proteins.
Tampa, United States. In Proteins, 2014
Involved in cell attachment and migration, cytoskeleton reorganization, signal transduction and other processes relevant to cancer research, tensins have recently been linked to functional properties of deleted in liver cancer 1 (DLC1) and a mitogen-activated protein kinases (MAPK), to cell migration in breast cancer, and to metastasis suppression in the kidney.