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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ras homolog gene family, member A

RhoA
Top mentioned proteins: Rhodopsin, Actin, V1a, CAN, Rac1
Papers using RhoA antibodies
G(alpha)12-mediated pathway promotes invasiveness of nasopharyngeal carcinoma by modulating actin cytoskeleton reorganization.
Supplier
Li Jun, In PLoS ONE, 2008
... Antibodies to Gα12, phospho-c-Jun, JNK, RhoA, α-tubulin were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5
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Ivaska Johanna et al., In The Journal of Cell Biology, 2006
... 9EG7 and MAB13 [BD]; MAB2252 [Millipore]), p120RasGAP and p190RhoGAP (BD), α-tubulin (Santa Cruz Biotechnology, Inc.), RhoA (Cell Signaling Technology), RFP (MBL), and ...
RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration
Supplier
Burridge Keith et al., In The Journal of Cell Biology, 2005
... pAbs against ICAM1 (for Western blotting) and mAb against RhoA were obtained from Santa Cruz Biotechnology, Inc ...
Endothelial cell cortactin coordinates intercellular adhesion molecule-1 clustering and actin cytoskeleton remodeling during polymorphonuclear leukocyte adhesion and transmigration
Supplier
Couraud Pierre-Olivier et al., In Journal of Neurochemistry, 2005
... M20 polyclonal Abs to rat PECAM-1, anti-SHP2 and anti-RhoA mAb were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Two distinct cytoplasmic regions of the β2 integrin chain regulate RhoA function during phagocytosis
Supplier
Caron Emmanuelle et al., In The Journal of Cell Biology, 2004
... (BD Biosciences), and rabbit anti-RhoA (119; Santa Cruz Biotechnology, Inc) ...
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Papers on RhoA
Direct measurement of oscillatory RhoA activity in embryonic cortical neurons stimulated with the axon guidance cue netrin-1 using FRET.
New
Lamarche-Vane et al., Montréal, Canada. In Biol Cell, Feb 2016
It is generally accepted that Rac1 and Cdc42 are positive regulators of axon outgrowth and guidance, while RhoA is a negative regulator.
Endothelin-1/endothelin A receptor axis activates RhoA GTPase in epithelial ovarian cancer.
New
Rosanò et al., Roma, Italy. In Life Sci, Feb 2016
Here, we set out to molecularly dissect whether RhoA GTPase activation is a mediator of ET-1 signaling controlling EOC cell migration.
Small GTPases in peroxisome dynamics.
Review
New
Peränen et al., Heidelberg, Germany. In Biochim Biophys Acta, Feb 2016
In its GTP-bound form RhoA activates a regulatory cascade involving Rho kinaseII and non-muscle myosinIIA.
RhoA mediates the expression of acidic extracellular pH-induced matrix metalloproteinase-9 mRNA through phospholipase D1 in mouse metastatic B16-BL6 melanoma cells.
New
Kato et al., Kōriyama, Japan. In Int J Oncol, Feb 2016
Small interfering RNA (siRNA) against RhoA, but not against Rac1 or Cdc42, significantly inhibited acidic pHe induction of MMP-9.
Novel Insights into the Roles of Rho Kinase in Cancer.
Review
New
Shi et al., Indianapolis, United States. In Arch Immunol Ther Exp (warsz), Feb 2016
UNASSIGNED: Rho-associated coiled-coil kinase (ROCK) is a major downstream effector of the small GTPase RhoA.
Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells.
New
Impact
Lennon-Duménil et al., France. In Nat Cell Biol, Jan 2016
Here, we show that the migration of immature DCs depends on two main actin pools: a RhoA-mDia1-dependent actin pool located at their rear, which facilitates forward locomotion; and a Cdc42-Arp2/3-dependent actin pool present at their front, which limits migration but promotes antigen capture.
Pathophysiological effects of RhoA and Rho-associated kinase on cardiovascular system.
Review
New
Zhou et al., Guangzhou, China. In J Hypertens, Jan 2016
In past decades, growing evidence from basic and clinical researches reveal that small guanosine triphosphate binding protein ras homolog gene family, member A (RhoA) and its main effector Rho-associated kinase (ROCK) play central and complex roles in cardiovascular systems, and increasing RhoA and ROCK activity is associated with a broad range of cardiovascular diseases such as congestive heart failure, atherosclerosis, and hypertension.
GPER inhibits diabetes-mediated RhoA activation to prevent vascular endothelial dysfunction.
New
Liu et al., Xi'an, China. In Eur J Cell Biol, Jan 2016
The RhoA/Rho-kinase pathway contributes to diabetic vascular complications, whereas estrogen can suppress Rho-kinase function.
Locally excitable Cdc42 signals steer cells during chemotaxis.
New
Impact
Meyer et al., Stanford, United States. In Nat Cell Biol, Jan 2016
Although Ras, Rac, Cdc42 and RhoA small GTPases all regulate chemotaxis, it has been unclear how they spatiotemporally control polarization and steering.
Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.
New
Impact
Wang et al., New York City, United States. In Cancer Cell, Jan 2016
These cells form the perivascular gastric stem cell niche, and Wnt5a produced from ILCs activates RhoA to inhibit anoikis in the E-cadherin-depleted cells.
Proinflammatory gene expression in patients undergoing mitral valve surgery and maze ablation for atrial fibrillation.
New
Yeh et al., Taiwan. In J Thorac Cardiovasc Surg, Jan 2016
Concordant with the gene expression difference between AF and SR patients, rapid pacing increased the expressions of SHC1, RHOA, PDGFA, and TRAF2 in HL-1 myocytes, implicating a causative effect of tachyarrhythmia on these genes.
Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes.
New
Impact
Samakovlis et al., Stockholm, Sweden. In Nat Cell Biol, Dec 2015
A dynamic transverse enrichment of atypical protein kinase C (aPKC) shifts the balance and transiently targets activated small GTPase RhoA, myosin phosphorylation and Rab11 vesicle trafficking to longitudinal junctions.
Cyclin A2: At the crossroads of cell cycle and cell invasion.
Review
New
Blanchard et al., Montpellier, France. In World J Biol Chem, Dec 2015
Its implication in the control of cytoskeletal dynamics and cell movement has unveiled its role in the modulation of RhoA activity.
Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction.
New
Impact
Brunet et al., Stanford, United States. In Cell Metab, Dec 2015
AMPK phosphorylation of the RHOA guanine nucleotide exchange factor NET1A inhibits extracellular matrix degradation, an early step in cell invasion.
The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease.
Review
Lutz et al., Göttingen, Germany. In Front Pharmacol, 2014
Rho-associated kinases ROCK1 and ROCK2 are serine/threonine kinases that are downstream targets of the small GTPases RhoA, RhoB, and RhoC.
The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth.
GeneRIF
Stegmüller et al., Göttingen, Germany. In Development, 2012
A Cdh1-APC/Smurf1/RhoA pathway that mediates axonal growth suppression in the developing mammalian brain.
Traumatic noise activates Rho-family GTPases through transient cellular energy depletion.
GeneRIF
Sha et al., Charleston, United States. In J Neurosci, 2012
Levels of active RhoA decrease significantly in auditory hair cells following traumatic noise.
A Salmonella typhimurium-translocated glycerophospholipid:cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions.
GeneRIF
Miller et al., Seattle, United States. In J Biol Chem, 2012
SseJ binding to RhoA is required for recruitment of SseJ to the endosomal network and for full Salmonella virulence
Left-right locomotor circuitry depends on RhoA-driven organization of the neuroepithelium in the developing spinal cord.
GeneRIF
Yoshida et al., Cincinnati, United States. In J Neurosci, 2012
RhoA functions to maintain neuroepithelial structures in the developing spinal cord and that proper organization of the neuroepithelium is required for appropriate left-right motor behavior.
Interleukin-8 induces the endothelial cell migration through the Rac 1/RhoA-p38MAPK pathway.
GeneRIF
Liu et al., Chengdu, China. In Eur Rev Med Pharmacol Sci, 2012
IL-8-Rac1/RhoA-p38MAPK signaling pathway plays a vital role in the IL-8-induced endothelial cell migration.
More papers using RhoA antibodies
To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front
Supplier
Bourne Henry R. et al., In The Journal of Cell Biology, 2004
... Mouse monoclonal antibody against RhoA was purchased from Santa Cruz Biotechnology, Inc ...
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility
Supplier
Schlaepfer David D. et al., In The Journal of Cell Biology, 2002
... Rabbit polyclonal anti-RhoA (sc-179) was obtained from Santa Cruz Biotechnology, Inc ...
Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement
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Mañes Santos et al., In The Journal of Cell Biology, 2001
... Anti–human PIPKIα, β, and γ, anti-myc clone 9E10, and anti-RhoA antibodies were obtained from Santa Cruz Biotechnology, Inc.; anti-phospho-ERM, -ERM, -pS ...
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
Supplier
Narumiya Shuh et al., In The Journal of Cell Biology, 2000
... to Cdc42 and C-20 to Ect2, and mouse mAb, B-8 to Cdc42 and 26C4 to RhoA, were purchased from Santa Cruz Biotechnology, Inc ...
ERK5 promotes Src-induced podosome formation by limiting Rho activation
Supplier
Martin G. Steven et al., In The Journal of Cell Biology, 1999
... (4F11) were obtained from Millipore; anti-Fra1, anti-GFP, anti-ROCK, anti-Rac1, anti-MEF2, anti-VP16, anti-CDC42, anti-myc (9E10), and anti-RhoA were obtained from Santa Cruz Biotechnology, Inc.; anti-GAPDH was obtained ...
Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them
Supplier
Formisano Pietro et al., In Journal of Cellular Physiology, 1999
... Rabbit polyclonal ERK1/2 (clone C-16G, used at 1:2,000 dilution) and mouse monoclonal RhoA (clone 26C4, used at 1:2,000 dilution) antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA), and ...
Tyrosine phosphorylation of focal adhesion kinase by PDGF is dependent on Ras in human hepatic stellate cells
Supplier
Ogata Itsuro et al., In Comparative Hepatology, 1999
... A monoclonal antibody against RhoA was from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells
Supplier
Mercurio Arthur M. et al., In The Journal of Cell Biology, 1997
... from Rita Falcioni, Regina Elena Cancer Institute, Rome, Italy); mouse anti-HA mAb (Roche Biochemicals); rabbit anti-RhoA polyclonal antibody (Santa Cruz Biotechnology); and anti-Rac1 (Transduction Laboratories).
Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells
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Ozanne Bradford W. et al., In The Journal of Cell Biology, 1997
... UK), anti-ERK2 (Transduction Laboratories, Lexington, KY), anti-phosphotyrosine (PY20; Transduction Laboratories), anti-human Rac (Upstate Biotechnology Inc.), anti-RhoA (Santa Cruz Biotechnology ...
The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA–GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis
Supplier
Sonnenberg Arnoud et al., In The Journal of Cell Biology, 1997
... phosphotyrosine (clones 10, 77, 21, 165, 102, 30, and RC20, respectively, obtained from Transduction Laboratories), RhoA (clone 26C4; Santa Cruz Biotechnology, Inc.), and vinculin (clone ...
Small GTPase Rin induces neurite outgrowth through Rac/Cdc42 and calmodulin in PC12 cells
Supplier
Nakamura Shun et al., In The Journal of Cell Biology, 1997
... Anti–c-Myc 9E10 antibody, anti-Cdc42 antibody and anti-RhoA antibody were purchased from Santa Cruz Biotechnology, Inc ...
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
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Mueller Bernhard K. et al., In The Journal of Cell Biology, 1997
... stained with an F-actin stain, Alexa Fluor-Phalloidin (Molecular Probes, Inc.), or with antibodies specific for RhoA (Santa Cruz Biotechnology) or the ROCK Rock1 ...
Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E–cdk2, and phosphorylation of the retinoblastoma protein
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Yamada Kenneth M. et al., In The Journal of Cell Biology, 1995
... Monoclonal antibodies against RhoA (Santa Cruz Biotechnology, Inc.) and Rac1 (Upstate ...
Force measurements in E-cadherin–mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42
Supplier
Dufour Sylvie et al., In The Journal of Cell Biology, 1994
... The anti-Rac and anti-RhoA mAbs were purchased from Upstate Biotechnology and Santa Cruz Biotechnology, Inc., respectively ...
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