Small GTPases in peroxisome dynamics.
Heidelberg, Germany. In Biochim Biophys Acta, Feb 2016
In its GTP-bound form RhoA activates a regulatory cascade involving Rho kinaseII and non-muscle myosinIIA.
Pathophysiological effects of RhoA and Rho-associated kinase on cardiovascular system.
More papers using
Guangzhou, China. In J Hypertens, Jan 2016
In past decades, growing evidence from basic and clinical researches reveal that small guanosine triphosphate binding protein ras homolog gene family, member A (RhoA) and its main effector Rho-associated kinase (ROCK) play central and complex roles in cardiovascular systems, and increasing RhoA and ROCK activity is associated with a broad range of cardiovascular diseases such as congestive heart failure, atherosclerosis, and hypertension.
ERK5 promotes Src-induced podosome formation by limiting Rho activation
In The Journal of Cell Biology, 1999
... (4F11) were obtained from Millipore; anti-Fra1, anti-GFP, anti-ROCK, anti-Rac1, anti-MEF2, anti-VP16, anti-CDC42, anti-myc (9E10), and anti-RhoA were obtained from Santa Cruz Biotechnology, Inc.; anti-GAPDH was obtained ... The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA–GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis
In The Journal of Cell Biology, 1997
... phosphotyrosine (clones 10, 77, 21, 165, 102, 30, and RC20, respectively, obtained from Transduction Laboratories), RhoA (clone 26C4; Santa Cruz Biotechnology, Inc.), and vinculin (clone ...