Modulating platelet reactivity through control of RGS18 availability.
Philadelphia, United States. In Blood, Jan 2016
We have shown previously that a critical node in the G-protein signaling network in platelets is formed by a scaffold protein, spinophilin (SPL), the tyrosine phosphatase, Src homology region 2 domain-containing phosphatase-1 (SHP-1), and the regulator of G-protein signaling family member, RGS18.
Identification of extracellularly phosphorylated membrane proteins.
Düsseldorf, Germany. In Proteomics, Oct 2015
Using this approach we identified novel phosphorylation sites on five ectophosphoproteins (NOTCH1, otopetrin 1, regulator of G-protein signalling 13 (RGS13), protein tyrosine phosphatase receptor type D isoform 3 (PTPRD), usherin isoform B (USH2A)).
Identification of novel immune phenotypes for allergic and nonallergic childhood asthma.
München, Germany. In J Allergy Clin Immunol, 2015
In parallel, expressions of anti-inflammatory IL37, proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2), and the neutrophil-associated genes CD93, triggering receptor expressed on myeloid cells 1 (TREM1), and regulator of G-protein signaling 13 (RGS13) were increased in patients with NA.