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Formyl peptide receptor 2

RFP, FPRL1, formyl peptide receptor-like 1
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, V1a, HAD, ACID, Actin
Papers using RFP antibodies
Extraction and immunoblotting of proteins from embryos.
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Akhtar Asifa, In PLoS Genetics, 2007
... Expression of UASP-GFP-Wde, UASP-Egg-RFP, UASP-POF-RFP and of endogenous Wde from the P insertion P{EP}EP2024 [50] in transgenic flies was done with ...
Copy-number variations associated with neuropsychiatric conditions
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Sans N et al., In Molecular Psychiatry, 2007
... The SureSilencing short-hairpin RNA plasmids cloned in p-RFP-C-RS were purchased from Origene (Rockville, MD, USA) ...
Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5
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Ivaska Johanna et al., In The Journal of Cell Biology, 2006
... MAB2252 [Millipore]), p120RasGAP and p190RhoGAP (BD), α-tubulin (Santa Cruz Biotechnology, Inc.), RhoA (Cell Signaling Technology), RFP (MBL), and GST, GFP, and ...
Notch-Delta signaling is required for spatial patterning and Muller glia differentiation in the zebrafish retina
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Fjose Anders et al., In BMC Neuroscience, 2004
... Induced expression of red fluorescent protein (RFP) from a UAS:RFP construct in larvae at 3 dpf demonstrated for both transgenic lines the presence of ...
Haploid selection in animals
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Moehring Amanda J. et al., In International Journal of Evolutionary Biology, 2003
... GFP and RFP transgenic flies ...
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Papers on RFP
Emodin ameliorates cisplatin-induced apoptosis of rat renal tubular cells in vitro by activating autophagy.
New
Sun et al., Nanjing, China. In Acta Pharmacol Sin, Feb 2016
The changes of morphology and RFP-LC3 fluorescence were observed under microscopy.
Imaging the Microenvironment of Pancreatic Cancer Patient-Derived Orthotopic Xenografts (PDOX) Growing in Transgenic Nude Mice Expressing GFP, RFP, or CFP.
New
Bouvet et al., San Diego, United States. In Cancer Lett, Jan 2016
The tumors are labeled by first passaging them orthotopically through transgenic nude mice expressing green fluorescent protein (GFP), red fluorescent protein (RFP), or cyan fluorescent protein (CFP).
Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A.
New
Baric et al., Chapel Hill, United States. In Mbio, Dec 2015
Using reverse genetics, we removed open reading frame 3 (ORF3) and replaced this region with a red fluorescent protein (RFP) gene to generate icPEDV-ΔORF3-RFP.
Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering.
New
Zou et al., Guangzhou, China. In Plos One, Dec 2015
In this study, we established a porcine Oct4 reporter system, wherein the endogenous Oct4 promoter directly controls red fluorescent protein (RFP).
Co-evolution with chicken class I genes.
Review
New
Kaufman, Cambridge, United Kingdom. In Immunol Rev, Sep 2015
In contrast to typical mammals that have many class I and class I-like genes, only two classical class I genes, two CD1 genes and some non-classical Rfp-Y genes are known in chicken, and all are found on the microchromosome that bears the MHC.
AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging.
New
Impact
Steinberg et al., Hamilton, Canada. In Cell Metab, Jul 2015
Markers of muscle autophagy including phosphorylation of Ulk1 Ser555 and Ser757 and aggregation of RFP-LC3 puncta are impaired.
The Human Cathelicidin Antimicrobial Peptide LL-37 and Mimics are Potential Anticancer Drugs.
Review
Isogai et al., Sendai, Japan. In Front Oncol, 2014
Indeed, previous studies have suggested that human LL-37 is involved in carcinogenesis via multiple reporters, such as FPR2 (FPRL1), epidermal growth factor receptor, and ERBb2, although LL-37 and its fragments and analogs also show anticancer effects in various cancer cell lines.
Annexin 1: a glucocorticoid-inducible protein that modulates inflammatory pain.
Review
Pei et al., Jingzhou, China. In Eur J Pain, 2014
Annexin 1, a glucocorticoid (GC)-inducible protein, can play an important role via formyl peptide receptor like 1 (FPR2/ALX, also known as FPRL1) in inflammatory pain modulation.
Coupling reporter expression to respiration detects active as well as dormant mycobacteria in vitro and in mouse tissues.
Krishnan et al., Lucknow, India. In Int J Mycobacteriol, 2014
METHODS: Putative promoter containing sequences were cloned upstream of a red fluorescent protein (RFP) gene.
Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags.
Impact
Peti-Peterdi et al., Los Angeles, United States. In Nat Med, 2013
The tracking of single cells in podocin-confetti mice featuring cell-specific expression of CFP, GFP, YFP or RFP revealed the simultaneous migration of multiple podocytes.
Transgenic Xenopus laevis for live imaging in cell and developmental biology.
Review
Ueno et al., Okazaki, Japan. In Dev Growth Differ, 2013
The stable transgenesis of genes encoding functional or spatially localized proteins, fused to fluorescent proteins such as green fluorescent protein (GFP) or red fluorescent protein (RFP), is an extremely important research tool in cell and developmental biology.
In vivo three-photon microscopy of subcortical structures within an intact mouse brain.
Impact
Xu et al., Ithaca, United States. In Nat Photonics, 2013
Vascular structures as well as red fluorescent protein (RFP)-labeled neurons within the mouse hippocampus are imaged.
Clinical impact of immune microenvironment in stage I lung adenocarcinoma: tumor interleukin-12 receptor β2 (IL-12Rβ2), IL-7R, and stromal FoxP3/CD3 ratio are independent predictors of recurrence.
Impact
Adusumilli et al., New York City, United States. In J Clin Oncol, 2013
RESULTS: Although a high density of stromal forkhead box P3 (FoxP3) -positive cells was associated with shorter recurrence-free probability (RFP; P = .043),
Phosphatidylinositol-3-kinase C2β and TRIM27 function to positively and negatively regulate IgE receptor activation of mast cells.
GeneRIF
Skolnik et al., New York City, United States. In Mol Cell Biol, 2012
study found that TRIM27 negatively regulates FcepsilonRI activation of KCa3.1 and downstream signaling by ubiquitinating and inhibiting PI3KC2beta; findings identify TRIM27 as an important negative regulator of mast cells in vivo
Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin.
GeneRIF
Dahlgren et al., Göteborg, Sweden. In J Immunol, 2012
Neutrophil activity induced by a cell-permeable peptide derived from the third intracellular loop of FPR2 is dose-dependently inhibited by membrane-permeable peptide inhibitor PBP10.
Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling.
GeneRIF
Flower et al., London, United Kingdom. In J Biol Chem, 2012
N-terminal region was dispensable for AnxA1-induced FPR2/ALX down-regulation in both the homologous and heterologous desensitization modes.
Role of the tripartite motif protein 27 in cancer development.
GeneRIF
Mittnacht et al., London, United Kingdom. In J Natl Cancer Inst, 2012
Trim27(-/-) mice (n = 14) were resistant to chemically induced skin cancer development (eight [57.2%] of 14 mice were tumor free) compared with Trim27(+/+) wild-type littermates (n = 13) (one [7.7%] of 13 mice was tumor free).
No evidence for the involvement of the lipoxin A4 receptor (FPR2/ALX ) gene in the susceptibility to coronary artery disease.
GeneRIF
Hersberger et al., In Clin Chem Lab Med, 2012
No evidence for the involvement of the lipoxin A4 receptor (FPR2/ALX ) gene in the susceptibility to coronary artery disease
TRIM involvement in transcriptional regulation.
Review
Losson et al., Illkirch-Graffenstaden, France. In Adv Exp Med Biol, 2011
These proteins include the transcriptional intermediary factor 1 (TIF1) regulators, the promyelocytic leukemia tumor suppressor PML and the RET finger protein (RFP).
ErythRED, a hESC line enabling identification of erythroid cells.
Impact
Elefanty et al., Australia. In Nat Methods, 2009
We describe a genetically modified hESC line, ErythRED, in which expression of RFP, controlled by regulatory sequences from the human beta-globin locus control region, is restricted to maturing erythroid cells.
More papers using RFP antibodies
UCSF chimera–a visualization system for exploratory research and analysis.
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Cavalli Giacomo, In PLoS ONE, 2003
... The UAS>Rbf1N-RFP construct (pJA024) was used for embryo injections to create transgenic fly lines ...
Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice
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Li Xiao-Jiang et al., In The Journal of Cell Biology, 2002
... for the following proteins were purchased from commercial sources: GFP (Av monoclonal antibody 632380), DsRed (RFP) (Clontech Laboratories, Inc.), 20S proteasome ...
Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle
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Komuro Issei et al., In The Journal of Cell Biology, 2002
... monoclonal anti-Cre (Sigma-Aldrich), rabbit polyclonal anti-PH3 (Upstate Biotechnology), mouse monoclonal anti-cyclinB1 (Neomarkers), and rabbit polyclonal anti-RFP (MBL International Corporation) ...
Establishment of medaka (Oryzias latipes) transgenic lines with the expression of green fluorescent protein fluorescence exclusively in germ cells: a useful model to monitor germ cells in a live vertebrate
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Schartl Manfred et al., In BMC Developmental Biology, 2000
... 3'UTR driven PGC-specific expression, the RFP- Zfnos1 3'UTR construct was injected in the Medaka Olvas transgenic strain (A) expressing GFP ...
The dynamin-related GTPase, Mgm1p, is a mitochondrial intermembrane space protein required for maintenance of fusion competent mitochondria
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Shaw J.M. et al., In The Journal of Cell Biology, 1999
... -RFP (mito-RFP), a BamHI/XhoI fragment containing RFP (the red fluorescent protein from the pDsRed vector; CLONTECH Laboratories, Inc.) was cloned ...
Interaction of trichohyalin with intermediate filaments: Three immunologically defined stages of trichohyalin maturation
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Hogan Brigid, In PLoS Biology, 1991
... For Lef1-RFP transgenic mice, a 6,713-basepair XbaI/NotI fragment ...
Statistical Principles in Experimental Design.
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Mansvelder Huibert D., In PLoS ONE, 1990
... Cells expressing mouse PSD-95 fused to RFP (Red Fluorescent Protein: dsRed2, Clontech) were excited using the ...
Graph Pad
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Bargmann Cornelia I et al., In Neural Development, 1988
... 10 ng/ul]; kyEx1229 (line 1) kyEx1387 (line 2) and kyEx1388 (line 3) [odr-3::unc-36 20 ng/ul, odr-1::RFP 2.5 ng/ul, elt-2::GFP 10 ng/ul].Additional transgenic arrays were kyEx822 [odr-3::nsy-4a ...
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