REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.
Ann Arbor, United States. In Environ Mol Mutagen, 2012
It is now well recognized that translesion DNA synthesis (TLS), especially through the activities of REV1 and DNA polymerase zeta (Polζ), is necessary for both ICL repair pathways operating throughout the cell cycle.
DNA polymerase zeta (pol zeta) in higher eukaryotes.
Pittsburgh, United States. In Cell Res, 2008
Most current knowledge about DNA polymerase zeta (pol zeta) comes from studies of the enzyme in the budding yeast Saccharomyces cerevisiae, where pol zeta consists of a complex of the catalytic subunit Rev3 with Rev7, which associates with Rev1.
Role of PSO genes in repair of DNA damage of Saccharomyces cerevisiae.
Porto Alegre, Brazil. In Mutat Res, 2003
Of the seven DNA repair genes involved in induced mutagenesis three PSO loci [PSO1/REV3, PSO8/RAD6, PSO9/MEC3] were allelic to already known repair genes, whereas three, PSO2/SNM1, PSO3/RNR4, and PSO4/PRP19 represent new genes involved in DNA repair and nucleic acid metabolism in S. cerevisiae.