Promoter methylation status of Ras-association domain family members in pheochromocytoma.
Gießen, Germany. In Front Endocrinol (lausanne), 2014
In this study, we observed inactivating DNA modifications for the RASSF members RASSF2, RASSF5A, RASSF9, and RASSF10, but not for the members RASSF3, RASSF4, RASSF5C, RASSF6, RASSF7, and RASSF8.
N-terminal RASSF family: RASSF7-RASSF10.
Birmingham, United Kingdom. In Epigenetics, 2011
RASSF1A (Ras Association Domain Family 1 isoform A) tumor suppressor gene is one of the most frequently epigenetically inactivated genes in a wide range of adult and children's cancers and could be a useful molecular marker for cancer diagnosis and prognosis.
Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma.
Gießen, Germany. In Oncol Rep, 2009
Here we analyzed the promoter methylation of 15 genes (RASSF1A, p16, MGMT, DAPK, RARbeta, MLH1, CDH1, GSTP1, RASSF2, RASSF4, RASSF5, MST1, MST2, LATS1, LATS2) in 54 HNSCC and in matching 23 normal tissues.
Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease.
Cardiff, United Kingdom. In Am J Med Genet B Neuropsychiatr Genet, 2007
We studied 23 positional/functional candidate genes from our linkage region on chromosome 10 (APBB1IP, ALOX5, AD037, SLC18A3, DKK1, ZWINT, ANK3, UBE2D1, CDC2, SIRT1, JDP1, NET7, SUPV3L1, NEN3, SAR1, SGPL1, SEC24C, CAMK2G, PP3CB, SNCG, CH25H, PLCE1, ANXV111) in the MRC genetic resource for LOAD.