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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

RAS-like, family 11, member B

RASL11B
RASL11B is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008] (from NCBI)
Top mentioned proteins: Dev, MUPP1, PDGFRA, TGF-beta, FIP1L1
Papers on RASL11B
Comparative analyses of lung transcriptomes in patients with alveolar capillary dysplasia with misalignment of pulmonary veins and in foxf1 heterozygous knockout mice.
Stankiewicz et al., Cincinnati, United States. In Plos One, 2013
Similar transcriptional changes were found in lungs of the postnatal day 0.5 Foxf1+/- mice when compared to their wildtype littermate controls; 14 genes, COL15A1, COL18A1, COL6A2, ESM1, FSCN1, GRINA, IGFBP3, IL1B, MALL, NOS3, RASL11B, MATN2, PRKCDBP, and SIRPA, were found common to both ACDMPV and Foxf1 heterozygous lungs.
Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations.
Myklebost et al., Oslo, Norway. In Cancer, 2012
These were rather focused and consistent with amplifications frequent in patient samples, involving the genes platelet-derived growth factor receptor A (PDGFRA), cysteine-rich hydrophobic domain 2 (CHIC2), FIP-like 1 (FIP1L1), ligand of numb-protein X1 (LNX1), RAS-like family 11 member B (RASL11B), and sec1 family domain containing 2 (SCFD2), probably a sign of continued tumor progression.
Gene expression profile of human lymphocytes exposed to (211)At alpha particles.
Schneeweiss et al., Jülich, Germany. In Radiat Res, 2010
Eight selected early-response genes that displayed a sustained up- or down-regulation (CD36, HSPA2, MS4A6A, NFIL3, IL1F9, IRX5, RASL11B and SULT1B1) were further validated in alpha-particle-irradiated lymphocytes of two human individuals using the TaqMan(R) RT-qPCR technique.
Rasl11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype.
GeneRIF
Mourrain et al., Paris, France. In Plos One, 2007
Rasl11b modifies the effect of Oep on mesendoderm development independently of the main known Oep output: the Nodal signaling pathway
Characterization of the amplicon on chromosomal segment 4q12 in glioblastoma multiforme.
von Deimling et al., Berlin, Germany. In Neuro Oncol, 2007
We applied multiplex ligation-dependent probe amplification to determine the gene dosage of PDGFRA, KIT, and KDR and the flanking genes USP46, RASL11B, LNX1, CHIC2, SEC3L1, and IGFBP7.
Cloning, genomic organization, and tissue-specific expression of the RASL11B gene.
GeneRIF
Lorkowski et al., Münster, Germany. In Biochim Biophys Acta, 2007
RASL11B gene is expressed in all tissues investigated, with highest levels in placenta & primary macrophages. RASL11B may play a role in TGF-beta1-mediated developmental processes & in pathophysiologies such as inflammation, cancer, and arteriosclerosis.
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