Cabozantinib in Thyroid Cancer.
Pisa, Italy. In Recent Pat Anticancer Drug Discov, Dec 2014
Actually, two Phase II trials of cabozantinib in DTC patients resistant to RAI are ongoing.
Evolving approaches to patients with advanced differentiated thyroid cancer.
Aurora, United States. In Endocr Rev, 2013
Advanced differentiated thyroid cancer (DTC), defined by clinical characteristics including gross extrathyroidal invasion, distant metastases, radioiodine (RAI) resistance, and avidity for 18-fluorodeoxyglucose (positron emission tomography-positive), is found in approximately 10-20% of patients with DTC.
Richter's syndrome: a report on 39 patients.
Houston, United States. In J Clin Oncol, 1993
Patients at all Rai stages and in complete response (CR) were at risk, including three CR patients with no residual disease at the level of detection by dual-parameter flow cytometry or restriction analysis for immunoglobulin (Ig) gene rearrangements.