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RAD9 homolog B

Rad9B
Top mentioned proteins: Rad9, Hus1, rad1, ACID, PCNA
Papers on Rad9B
Up-regulation of endothelial nitric oxide synthase (eNOS), silent mating type information regulation 2 homologue 1 (SIRT1) and autophagy-related genes by repeated treatments with resveratrol in human umbilical vein endothelial cells.
Inoue et al., Nara, Japan. In Br J Nutr, 2013
In addition, resveratrol treatment down-regulated the expression of the cell-cycle checkpoint control RAD9 homologue B (RAD9B) gene.
Clamping down on mammalian meiosis.
Lieberman et al., New York City, United States. In Cell Cycle, 2013
Based on these studies and the high-level expression of the paralogous proteins RAD9B and HUS1B in testis, we propose a model in which multiple alternative 9-1-1 clamps function during mammalian meiosis to ensure genome maintenance in the germline.
Rad9B responds to nucleolar stress through ATR and JNK signalling, and delays the G1-S transition.
GeneRIF
Freire et al., Santa Cruz de Tenerife, Spain. In J Cell Sci, 2012
Rad9B responds to nucleolar stress after the activation of JNK-dependent stress signalling and ATR-dependent DNA damage response pathways, and actively accumulates within nucleoli, where it does not cause a transcription block.
Mouse Rad9b is essential for embryonic development and promotes resistance to DNA damage.
Lieberman et al., New York City, United States. In Dev Dyn, 2010
A paralogue of RAD9 (named RAD9B) has been identified.
The Rad9A checkpoint protein is required for nuclear localization of the claspin adaptor protein.
Davey et al., Kingston, Canada. In Cell Cycle, 2010
We also show that in meS cells the Rad9A paralog, Rad9B, is also capable of affecting Claspin localization.
Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity.
GeneRIF
Lieberman, New York City, United States. In J Cell Biochem, 2006
The encoded mammalian proteins participate in promoting resistance to DNA damage, cell cycle checkpoint control, DNA repair, and apoptosis.
Identification and characterization of RAD9B, a paralog of the RAD9 checkpoint gene.
Karnitz et al., Rochester, United States. In Genomics, 2003
We have identified a novel RAD9 paralog, dubbed RAD9B, in humans and mice.
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