A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes
In PLoS ONE, 2008
... to HRP (Santa Cruz Biotechnology, Santa Cruz, CA), anti-Ras (Santa Cruz Biotechnology, Santa Cruz, CA), anti-Rab5 (Santa Cruz Biotechnology, Santa Cruz, CA), anti-AKT ... Lipid rafts, detergent-resistant membranes, and raft targeting signalsmore suppliers
In Cell Death & Disease, 2005
... Ab-3 in the manuscript), anti-FLAG (M2, Sigma), anti-Fyn (Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-Rab5 (Santa Cruz Biotechnology) and horseradish peroxidase-conjugated anti-rabbit ...
Rab, Arf and Arl-Regulated Membrane Traffic in Cortical Neuron Migration.
Singapore, Singapore. In J Cell Physiol, Dec 2015
Rab5 and Rab11, which are key modulators of endocytosis and endocytic recycling respectively, ensure proper surface expression and distribution of N-cadherin, a key adhesion protein that tethers migrating neurons to the radial glia fiber tracts during pia-directed migration.
Identification of an oncogenic RAB protein.
New York City, United States. In Science, Nov 2015
In a short hairpin RNA screen for genes that affect AKT phosphorylation, we identified the RAB35 small guanosine triphosphatase (GTPase)-a protein previously implicated in endomembrane trafficking-as a regulator of the phosphatidylinositol 3'-OH kinase (PI3K) pathway.
Gatekeepers Controlling GPCR Export and Function.
More papers using
Paris, France. In Trends Pharmacol Sci, Oct 2015
A specific ER-resident gatekeeper, prenylated Rab acceptor family 2 (PRAF2), is involved in GB1 retention and prevents its progression into the biosynthetic pathway.