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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

RAB3B, member RAS oncogene family

may play a role in secretory granule function and exocytosis in pancreatic acinar cells [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: Rab3A, Rab5, Rab3D, ACID, HAD
Papers on Rab3B
Combined analysis identifies six genes correlated with augmented malignancy from non-small cell to small cell lung cancer.
Shou et al., Beijing, China. In Tumour Biol, Oct 2015
Transcript levels of BUB1, E2F1, ESPL1, GTSE1, RAB3B, and U2AF2 were found significantly elevated from normal, ADC, SQC, LCC to SCLC.
Insulin regulates Rab3-Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes.
Holman et al., Bath, United Kingdom. In Diabetologia, Aug 2015
RESULTS: We identified Rab3B as a new candidate insulin-stimulated G-protein in adipocytes.
miR-200b as a prognostic factor targets multiple members of RAB family in glioma.
Jiang et al., Changsha, China. In Med Oncol, 2014
Members of RAB family, RAB21, RAB23, RAB18 and RAB3B were predicted to be novel targets of miR-200b.
miR-200b as a prognostic factor in breast cancer targets multiple members of RAB family.
Xie et al., Guangzhou, China. In J Transl Med, 2013
Members of RAB family, RAB21, RAB23, RAB18 and RAB3B were predicted to be the targets of miR-200b.
Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function.
Chen et al., Changchun, China. In Neurotoxicology, 2013
After cisplatin treatment, we observed significant down-regulation of mRNA for several genes related to synaptic function genes, including Camk2a, Camk2b, Vglut1, Snap25 and Rab3b, whereas pretreatment with TSA elevated mRNA levels of these genes.
Foetal stem cell derivation & characterization for osteogenic lineage.
Raj et al., Chennai, India. In Indian J Med Res, 2013
The undifferentiated MSCs expressed RAB3B, candidate marker for stemness in MSCs.
The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.
Carter et al., London, United Kingdom. In Blood, 2012
We identify new endogenous components of the WPB: Rab3B, Rab3D, and the Rab27A/Rab3 effector Slp4-a (granuphilin), and determine their role in WPB exocytosis.
[Study on gene differential expressions of substance and energy metabolism in chronic superficial gastritis patients of Pi deficiency syndrome and of pi-wei hygropyrexia syndrome].
Wang et al., Guangzhou, China. In Zhongguo Zhong Xi Yi Jie He Za Zhi, 2012
Genes correlated to protein metabolism included ASRGL1, AARSD1, EBNA1BP2, PUM2, MRPL52, C120RF65, PSMB8, PSME2, UBA7, RNF11, FBXO44, ZFYVE26, CHMP2A, SSR4, SNX4, RAB3B, RABL2A, GOLGA2, KDELR1, PHPT1, ACPP, PTPRF, CRKL, HDAC7, ADPRHL2, B3GNT1, ST8SIA4, DDOST, and FUT9, mainly involved in the biosynthesis processes of protein, ubiquitination, targeted transport and post-translation modification.
Crystal structure of inactive form of Rab3B.
Qi et al., Wuhan, China. In Biochem Biophys Res Commun, 2012
The structure of Rab3B:GDP complex was solved to 1.9A resolution and the structural base comparison with other Rab3 members provides a structural basis for the GDP/GTP switch in controlling the activity of small GTPase.
Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival.
Cheung et al., Singapore, Singapore. In Mol Cell Biol, 2012
Moreover, we demonstrate that NKX3-1, AR, and FoxA1 promote prostate cancer cell survival by directly upregulating RAB3B, a member of the RAB GTPase family.
Release of TNF-α from macrophages is mediated by small GTPase Rab37.
Tsuboi et al., Nagasaki, Japan. In Eur J Immunol, 2011
Rab3B, Rab27B, Rab30, Rab33A, Rab37, and Rab40C) being upregulated during the inflammation and proliferation/migration phase of skin repair.
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning.
Südhof et al., Stanford, United States. In Proc Natl Acad Sci U S A, 2011
Presynaptic forms of long-term plasticity at excitatory and inhibitory synapses generally are mediated by a common Rab3/RIM-dependent pathway, with various types of synapses using distinct Rab3 isoforms.
Functional molecular morphology of anterior pituitary cells, from hormone production to intracellular transport and secretion.
Osamura et al., Ichihara, Japan. In Med Mol Morphol, 2011
CLSM observation of rab3B and SNARE proteins such as SNAP-25 and syntaxin revealed that both rab3B and SNARE system proteins play an important role and work together as the exocytotic machinery in anterior pituitary cells.
Molecular morphology of pituitary cells, from conventional immunohistochemistry to fluorescein imaging.
Osamura et al., Chiba, Japan. In Molecules, 2010
CLSM observation of rab3B and SNARE proteins such as SNAP-25 and syntaxin has revealed that both rab3B and SNARE system proteins play important roles and work together as the exocytotic machinery in anterior pituitary cells.
In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets.
Hanley et al., Manchester, United Kingdom. In J Endocrinol, 2010
These results support an important inter-species difference in regulating insulin exocytosis where RAB3B is the most expressed isoform in human islets.
Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression.
Isacson et al., Belmont, United States. In Proc Natl Acad Sci U S A, 2010
RAB3B improves dopamine handling and storage capacity at presynaptic terminals, and confers protection to vulnerable DA neurons.
The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells.
Wu et al., Chongqing, China. In Proc Natl Acad Sci U S A, 2009
Rab3b/3c-positive recycling vesicles are involved in and may constitute one of the recycling compartments in exogenous antigen cross-presentation.
Inhibition of Rab3B expression attenuates Ca(2+)-dependent exocytosis in rat anterior pituitary cells.
Zorec et al., Cambridge, United Kingdom. In Nature, 1993
Rab3A is highly expressed in brain, whereas Rab3B is the major form found in rat anterior pituitary gland.
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