Role of the GTPase Rab1b in ebolavirus particle formation.
Tokyo, Japan. In J Virol, 2010
The authors demonstrate that Rab1b-activated GBF1 and ARF1 are involved in Ebolavirus virion formation, suggesting that both the COPII and COPI transport systems play a role in Ebolavirus VP40-mediated particle formation.
Rheb and mTOR regulate neuronal polarity through Rap1B.
Münster, Germany. In J Biol Chem, 2008
Inhibition of PI3K or mTOR reduced the level of Rap1B, which acts downstream of Rheb and mTOR. The ubiquitin E3 ligase Smurf2 mediates the restriction of Rap1B by initiating its degradation.