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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

RAB14, member RAS oncogene family

Rab14
may regulate neurotransmitter release [RGD, Feb 2006] (from NCBI)
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Top mentioned proteins: miR, POLYMERASE, Rab5, AS160, Akt
Papers on Rab14
microRNA-338-3p functions as a tumor suppressor in human non‑small‑cell lung carcinoma and targets Ras-related protein 14.
New
Xiao et al., Luoyang, China. In Mol Med Report, Feb 2015
Of note, ectopic miR‑338-3p expression significantly inhibited Ras‑related protein 14 (RAB14) mRNA and protein expression, and reduced luciferase reporter activity containing the RAB14 3'-untranslated region through the first binding site.
MIR144 and MIR451 regulate human erythropoiesis via RAB14.
New
Civin et al., Baltimore, United States. In Br J Haematol, Feb 2015
In this study, we found RAB14 is a direct target of both MIR144 and MIR451.
MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Yuan et al., Guangzhou, China. In Tumour Biol, 2014
The results also demonstrated that miR-451 directly targeted ras-related protein 14 (RAB14).
Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs.
McGraw et al., New York City, United States. In Mol Biol Cell, 2013
Here we establish that RAB10 and RAB14 are key regulators of GLUT4 trafficking that function at independent, sequential steps of GLUT4 translocation.
Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells.
GeneRIF
Barr et al., Oxford, United Kingdom. In Dev Cell, 2012
FAM116 and Rab14 therefore define an endocytic recycling pathway needed for ADAM protease trafficking and regulation of cell-cell junctions.
Identification of direct targets for the miR-17-92 cluster by proteomic analysis.
Ouchida et al., Okayama, Japan. In Proteomics, 2011
Among these candidate targets, we validated one direct target, RAB14.
MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14).
GeneRIF
Chen et al., Nanjing, China. In Oncogene, 2011
Data suggest that targeting with the miR-451/RAB14 interaction might serve as a novel therapeutic application to treat NSCLC patients.
KIF16B/Rab14 molecular motor complex is critical for early embryonic development by transporting FGF receptor.
GeneRIF
Hirokawa et al., Tokyo, Japan. In Dev Cell, 2011
The kinesin-3 motor KIF16B/Rab14 complex acts in biosynthetic Golgi-to-endosome traffic of the fibroblast growth factor receptor (FGFR) during early embryonic development.
Functional cross-talk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4.
GeneRIF
Shin et al., Kyoto, Japan. In Mol Biol Cell, 2010
These findings suggest that Rab14 and Rab4 act sequentially, together with RUFY1.
Chlamydia trachomatis intercepts Golgi-derived sphingolipids through a Rab14-mediated transport required for bacterial development and replication.
GeneRIF
Damiani et al., Mendoza, Argentina. In Plos One, 2009
Data show that Rab14 facilitates the delivery of sphingolipids required for bacterial development and replication from the Golgi to chlamydial inclusions.
Isolation, sequence identification and tissue expression distribution of three novel porcine genes--RAB14, S35A3 and ITM2A.
Gao et al., Kunming, China. In Mol Biol Rep, 2008
The nucleotide sequence analysis of these three genes revealed that porcine RAB14 gene encodes a protein of 215 amino acids that contains the conserved putative Ras-related protein Rab-14 domain and has high homology with the Ras-related protein Rab-14 (RAB14) of four species--human and mouse (99%) and rat (100%), dictyostelium discoideum (71%).
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.
Impact
Neefjes et al., Amsterdam, Netherlands. In Nature, 2007
AKT1 is activated by the S. typhimurium effector SopB, which promotes intracellular survival by controlling actin dynamics through PAK4, and phagosome-lysosome fusion through the AS160 (also known as TBC1D4)-RAB14 pathway.
Differential expression of proteins in rat plasma exposed to benzene.
Kim et al., Seoul, South Korea. In Proteomics, 2004
The overexpressed proteins (inhibitor of kappaB-like protein, GTP-binding protein rab14, T-cell receptor alpha chain, and somatostatin transactivating factor-1) were detected only in groups inhaling benzene for 6 weeks.
The phagosome proteome: insight into phagosome functions.
Desjardins et al., Grenoble, France. In J Cell Biol, 2001
A series of unexpected proteins not previously described along the endocytic/phagocytic pathways were also identified, including the apoptotic proteins galectin3, Alix, and TRAIL, the anti-apoptotic protein 14-3-3, the lipid raft-enriched flotillin-1, the anti-microbial molecule lactadherin, and the small GTPase rab14.
rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain.
Scheller et al., Stanford, United States. In J Biol Chem, 1992
Four additional clones, rab12, rab13, rab14, and rab15, revealed unique sequences and are new members of the rab family of LMW GTP-binding proteins.
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