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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

RAB13, member RAS oncogene family

may regulate neurotransmitter release [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: Rab5, AGE, Occludin, MAPK, iMpact
Papers using Rab13 antibodies
Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells
Fölsch Heike et al., In The Journal of Cell Biology, 2006
... RNAi constructs targeting human Rab13 (oligo IDs V2LHS_171155, V2LHS_278139, and V2LHS_171156) ...
Papers on Rab13
ANXA1Ac₂₋₂₆ peptide reduces ID1 expression in cervical carcinoma cultures.
Rodrigues-Lisoni et al., Ribeirão Preto, Brazil. In Gene, Nov 2015
Six genes were selected and the expression results of 5 up-regulated genes (TPT1, LDHA, NCOA3, HIF1A, RAB13) and one down-regulated gene (ID1) were research by real time quantitative PCR.
Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery.
Weigert et al., Copenhagen, Denmark. In Diabetologia, Aug 2015
RESULTS: Pathway analysis of differentially regulated genes upon exercise revealed upregulation of regulators of GLUT4 (SLC2A4RG, FLOT1, EXOC7, RAB13, RABGAP1 and CBLB), glycolysis (HK2, PFKFB1, PFKFB3, PFKM, FBP2 and LDHA) and insulin signal mediators in diabetic participants compared with controls.
Bioinformatics analysis reveals disturbance mechanism of MAPK signaling pathway and cell cycle in Glioblastoma multiforme.
Zou et al., Shenyang, China. In Gene, 2014
Among them, ras-related protein rab-13(RAB13), neuroblastoma breakpoint family member 10 (NBPF10) and disks large homologue 4 (DLG4) were found to be involved in GBM for the first time.
RAB13 regulates Sertoli cell permeability barrier dynamics through protein kinase A.
Liu et al., In J Mol Endocrinol, 2013
Using primarily cultured Sertoli cells in vitro with an established tight junction permeability barrier that mimics the BTB in vivo, RAB13 was shown to decrease during the testosterone-induced TJ integrity enhancement, accompanied with an increment in protein kinase A (PKA) activity.
Direct RNA sequencing mediated identification of mRNA localized in protrusions of human MDA-MB-231 metastatic breast cancer cells.
Nielsen et al., Århus, Denmark. In J Mol Signal, 2012
RESULTS: In the hereby identified group of protrusion localized mRNA some previously were described to be localized exemplified by mRNA for Ras-Related protein 13 (RAB13) and p0071 (Plakophilin-4/PKP4).
Identification of novel AR-targeted microRNAs mediating androgen signalling through critical pathways to regulate cell viability in prostate cancer.
Li et al., Shanghai, China. In Plos One, 2012
(1) miR-19a is directly up-regulated by AR, and represses SUZ12, RAB13, SC4MOL, PSAP and ABCA1, respectively.
Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells.
Väänänen et al., Turku, Finland. In J Histochem Cytochem, 2012
It is suggested that Rab13 is associated with a putative secretory function in osteoclasts.
Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells.
Rha et al., Seoul, South Korea. In Bmc Genomics, 2011
Significant genes including ACTN1, CCND1, HCLS1, ITGB5, PFN2, PTPRC, RAB13, and WAS, which are adhesion-related molecules that were identified by both SAM and gene set analysis, and showed interaction in the genetic network with the integrin signaling pathway.
Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53.
Wang et al., China. In Mol Psychiatry, 2011
Knockdown of dysbindin-1, like knockdown of p53, greatly decreases the expressions of the p53 target genes coronin 1b and rab13, which are required for neurite outgrowth.
Small GTPase Rab12 regulates constitutive degradation of transferrin receptor.
Fukuda et al., Sendai, Japan. In Traffic, 2011
TfR is constitutively degraded by a Rab12-dependent pathway (presumably from recycling endosomes to lysosomes), which is independent of the conventional degradation pathway.
Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis.
Horowitz et al., Cleveland, United States. In J Biol Chem, 2011
Rab13 associates with Grb2, targeting Syx and RhoA to Tyr(1175)-phosphorylated VEGFR2 at the leading edge.
Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells.
Klip et al., Toronto, Canada. In Proc Natl Acad Sci U S A, 2010
Rab13 and Rab8A are Rab-GTPases activated by insulin and downstream of AS160 they regulate traffic of GLUT4 vesicles.
Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2.
Sasaki et al., Tokushima, Japan. In Mol Cell Biol, 2010
show that Rab13 regulates neurite outgrowth in the rat pheochromocytoma cell line PC12 through an interaction with JRAB/MICAL-L2.
RAB13 participates in ectoplasmic specialization dynamics in the rat testis.
Lau et al., New York City, United States. In Biol Reprod, 2009
RAB13 functions in ectoplasmic specialization dynamics in the testis.
Short-term effects of adolescent methylphenidate exposure on brain striatal gene expression and sexual/endocrine parameters in male rats.
Laviola et al., Roma, Italy. In Ann N Y Acad Sci, 2006
These genes mediate survival of immature cells after contact with newly produced axonal matrix (laminin B1, collagens, integrin alpha 6) and stabilization of myelinating glia-axon contacts (RAB13, contactins 3 and 4).
Transcript profiling in peripheral T-cell lymphoma, not otherwise specified, and diffuse large B-cell lymphoma identifies distinct tumor profile signatures.
Miller et al., Tucson, United States. In Mol Cancer Ther, 2005
Highly overexpressed oncogenes unique to PTCL-NOS are SPI1, STK6, alpha-PDGFR, and SH2D1A, whereas in DLBCL they are PIM1, PIM2, LYN, BCL2A1, and RAB13.
Differentiation of the epithelial apical junctional complex during mouse preimplantation development: a role for rab13 in the early maturation of the tight junction.
Fleming et al., Southampton, United Kingdom. In Mech Dev, 2000
We also found that rab13, a small GTPase previously localized to the TJ, is expressed at all stages of preimplantation development and relocates from the cytoplasm to the site of AJC biogenesis from compaction onwards with rab13 and ZO-1alpha- co-localizing precisely.
A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells.
Louvard et al., Paris, France. In J Cell Biol, 1994
In this work, we have isolated a cDNA clone from a human intestinal cDNA library encoding a small GTPase, rab13, closely related to the yeast Sec4 protein.
rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain.
Scheller et al., Stanford, United States. In J Biol Chem, 1992
Four additional clones, rab12, rab13, rab14, and rab15, revealed unique sequences and are new members of the rab family of LMW GTP-binding proteins.
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