A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.more suppliers
In PLoS ONE, 2004
... (T6199, Sigma-Aldrich Ltd, Gillingham, Kent, UK); GTPase Rap1 (610196), endosomal vesicle markers EEA1 (610457) and Rab11 (610656) (all BD Transduction Laboratories, Oxford UK); rabbit anti- Gαq Ab (E-17) (SC-393, Santa Cruz Biotechnology Inc/Insight Biotechnology Ltd, Wembley, ...
Endocytic trafficking of glycosphingolipids in sphingolipid storage diseases.
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Rochester, United States. In Philos Trans R Soc Lond B Biol Sci, 2003
Overexpression of wild-type rab7 or rab9 (but not rab11) in Niemann-Pick C fibroblasts results in correction of lipid trafficking defects, including restoration of Golgi targeting of fluorescent lactosylceramide and endogenous GM1 ganglioside (monitored by the transport of fluorescent cholera toxin), and a dramatic reduction in accumulation of intracellular cholesterol.