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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

RAB11A, member RAS oncogene family

Rab11, Rab11a
The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] (from NCBI)
Top mentioned proteins: Rab5, V1a, CAN, Transferrin, ACID
Papers using Rab11 antibodies
Regulation of vascular endothelial growth factor receptor 2 trafficking and angiogenesis by Golgi localized t-SNARE syntaxin 6
Singh Rakesh K., In PLoS ONE, 2010
... Abs against Arf1, Arf6, and Rab11 were from Abcam (ab108347, Cambridge, MA), Thermo ...
One-step isolation of plasma membrane proteins using magnetic beads with immobilized concanavalin A.
Caplan Steve H., In PLoS ONE, 2007
... Antibody #610657 to Rab11A/Rab11B was from BD Biosciences.
Dual specificity of the interfacial inhibitor brefeldin a for arf proteins and sec7 domains.
Caplan Steve H., In PLoS ONE, 2005
... For the EGFP fusions of Rab4b and Rab11, Rab4b and Rab11 cDNAs were cloned into pEGFPC2 (Clontech).
A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.
Rappoport Joshua Z., In PLoS ONE, 2004
... (T6199, Sigma-Aldrich Ltd, Gillingham, Kent, UK); GTPase Rap1 (610196), endosomal vesicle markers EEA1 (610457) and Rab11 (610656) (all BD Transduction Laboratories, Oxford UK); rabbit anti- Gαq Ab (E-17) (SC-393, Santa Cruz Biotechnology Inc/Insight Biotechnology Ltd, Wembley, ...
Endosomes generate localized Rho–ROCK–MLC2–based contractile signals via Endo180 to promote adhesion disassembly
Isacke Clare M. et al., In The Journal of Cell Biology, 2000
... Mouse anti–human MYPT1, ROCK1, ROCK2, ZIP kinase, EEA1, and Rab11 were obtained from BD Biosciences.
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Papers on Rab11
Occupation of nucleotide in the binding pocket is critical to the stability of Rab11A.
Park et al., Seoul, South Korea. In Protein Expr Purif, Feb 2016
Here, we purified wild type, active mutant and inactive mutant of Rab11A.
Specific role of cytoplasmic dynein in the mechanism of action of an antitumor molecule, Amblyomin-X.
Chudzinski-Tavassi et al., São Paulo, Brazil. In Exp Cell Res, Jan 2016
In addition, Amblyomin-X was found to interact with dynein, increased Rab11A protein expression and Rab11A co-localization with the light-intermediate chain 2 (LIC2) of dynein.
TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic.
Tooze et al., Frankfurt am Main, Germany. In Embo J, Jan 2016
We have previously identified the TBC domain-containing protein, TBC1D14, as a negative regulator of autophagy that controls delivery of membranes from RAB11-positive recycling endosomes to forming autophagosomes.
Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy.
Björklund et al., Dundee, United Kingdom. In Cell Rep, Jan 2016
Mevalonate pathway effects on cell size and protein density are mediated through geranylgeranylation of the small GTPase RAB11, which is required for basal autophagic flux.
Recycling and Endosomal Sorting of Protease-activated Receptor-1 is Distinctly Regulated by Rab11A and Rab11B.
Trejo et al., San Diego, United States. In J Biol Chem, Jan 2016
We found that siRNA-mediated depletion of Rab11B and not Rab11A blocks PAR1 recycling, which enhanced receptor lysosomal degradation.
Purification, crystallization and X-ray crystallographic analysis of human RAB11(S20V), a constitutively active GTP-binding form.
Park et al., Kyŏngsan, South Korea. In Acta Crystallogr Sect F Struct Biol Commun, Oct 2015
RAB11, a member of the Ras superfamily of small G proteins, is involved in the regulation of vesicle trafficking during endosome recycling.
Deciphering Mineral Homeostasis in Barley Seed Transfer Cells at Transcriptional Level.
Borg et al., Slagelse, Denmark. In Plos One, 2014
Interestingly, the protein sorting and recycling factors Exoc7, Cdc1, Sec23A, and Rab11A contributed to the response as well as the polar distributors of metal-transporters ensuring the directional flow of minerals.
MicroRNA-320a inhibits proliferation and invasion of breast cancer cells by targeting RAB11A.
Chen et al., Shanghai, China. In Am J Cancer Res, 2014
We identified Rab11a as a direct target of miR-320a and showed that its expression was upregulated in tumor samples and inversely correlated with the expression of miR-320a.
RAB11-mediated trafficking in host-pathogen interactions.
Bier et al., San Diego, United States. In Nat Rev Microbiol, 2014
One host protein that is targeted by invading pathogens is the small GTPase RAB11, which functions in vesicular trafficking.
Identification of mutant genes with high-frequency, high-risk, and high-expression in lung adenocarcinoma.
Mei et al., Shanghai, China. In Thorac Cancer, 2014
No base mutation of cyclin C (CCNC) or RAB11A was recorded.
A Rab11A/myosin Vb/Rab11-FIP2 complex frames two late recycling steps of langerin from the ERC to the plasma membrane.
Salamero et al., Paris, France. In Traffic, 2012
Rab11A/myosin Vb/Rab11-FIP2 complex frames two late recycling steps of langerin from the ERC to the plasma membrane
TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.
Tooze et al., London, United Kingdom. In J Cell Biol, 2012
TBC1D14 binds activated Rab11 but is not a GAP for Rab11, and loss of Rab11 prevents TBC1D14-induced tubulation of recycling endosomes.
Deficient Rab11 activity underlies glucose hypometabolism in primary neurons of Huntington's disease mice.
Difiglia et al., United States. In Biochem Biophys Res Commun, 2012
These results suggest that deficient activity of Rab11 is a novel mechanism for glucose hypometabolism in Huntington's disease.
LMTK1/AATYK1 is a novel regulator of axonal outgrowth that acts via Rab11 in a Cdk5-dependent manner.
Hisanaga et al., Tokyo, Japan. In J Neurosci, 2012
Enhanced axonal outgrowth is diminished by inactivation of Rab11A, placing LMTK1 upstream of Rab11A.
Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway.
Gether et al., Copenhagen, Denmark. In J Biol Chem, 2012
Our data suggest a selective role of PICK1 in clustering and reducing the recycling rates of PDZ domain binding partners sorted to the Rab11-dependent recycling pathway.
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.
Gissen et al., Birmingham, United Kingdom. In Nat Genet, 2010
We show that VIPAR forms a functional complex with VPS33B that interacts with RAB11A.
Estrogen modulation of hypothalamic neurons: activation of multiple signaling pathways and gene expression changes.
Rønnekleiv et al., Portland, United States. In Steroids, 2005
Some of these include gec-1, PI3-kinase p55gamma, rab11a GTPase, synaptobrevin2, synaptogyrin, taxilin, Ca2+-dependent activator protein for secretion (CAPS) and a number of proteins containing pleckstrin homology domains-domains that are involved in plasma membrane targeting of their host protein.
Endocytic trafficking of glycosphingolipids in sphingolipid storage diseases.
Pagano, Rochester, United States. In Philos Trans R Soc Lond B Biol Sci, 2003
Overexpression of wild-type rab7 or rab9 (but not rab11) in Niemann-Pick C fibroblasts results in correction of lipid trafficking defects, including restoration of Golgi targeting of fluorescent lactosylceramide and endogenous GM1 ganglioside (monitored by the transport of fluorescent cholera toxin), and a dramatic reduction in accumulation of intracellular cholesterol.
Malignant progression in Barrett's esophagus: pathology and molecular biology.
Siewert et al., München, Germany. In Recent Results Cancer Res, 1999
Increased expression of one of these proteins, rab11, has been described in low-grade, but not high-grade dysplasia.
Regulation of membrane transport through the endocytic pathway by rabGTPases.
van der Sluijs et al., Utrecht, Netherlands. In Mol Membr Biol, 1999
Several of them, including rab5, rab4 and rab11, are localized to early endocytic organelles where they regulate distinct events in the transferrin receptor pathway.
More papers using Rab11 antibodies
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor
Balla Tamas et al., In The Journal of Cell Biology, 1995
... GFP-tagged versions of the Rab proteins (Rab4, Rab5, Rab7, and Rab11) were created in the pEGFP–C1 plasmids (CLONTECH Laboratories, Inc.) after PCR ...
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