Rab11-FIP3 is a cell cycle-regulated phosphoprotein.
Glasgow, United Kingdom. In Bmc Cell Biol, 2011
BACKGROUND: Rab11 and its effector molecule, Rab11-FIP3 (FIP3), associate with recycling endosomes and traffic into the furrow and midbody of cells during cytokinesis.
The Rab11 pathway is required for influenza A virus budding and filament formation.
Cambridge, United Kingdom. In J Virol, 2010
We find that cellular Rab11 (a small GTP-binding protein involved in endocytic recycling) and Rab11-family interacting protein 3 ([FIP3] which plays a role in membrane trafficking and regulation of actin dynamics) are both required to support the formation of filamentous virions, while Rab11 is additionally involved in the final budding step of spherical particles.
Purification and functional properties of Rab11-FIP3.
In Methods Enzymol, 2004
Rab11-FIP3, a member of this Rab11-binding protein family, in addition to interacting with Rab11, is also capable of interaction with members of the ADP-Ribosylation Factor (ARF) GTPase family.