Differential expression of S100A2 and S100A4 during progression of human prostate adenocarcinoma.
Cleveland, United States. In J Clin Oncol, 2003
PATIENTS AND METHODS: Expression pattern of S100A2 and S100A4 was determined in normal human prostate epithelial cells (NHPE); virally transformed prostate epithelial cells (PZ-HPV-7); several human prostate carcinoma cells (22Rv1, DU145, LNCaP, and PC3); tissue samples obtained during transuretheral prostatic resection from patients with benign prostate hyperplasia (BPH), prostatitis, and adenocarcinoma; and paraffin-embedded sections from pair-matched benign and cancer specimens of different tumor grade.
Is the progress zone model a victim of progress?
In Cell, 2002
The prevailing view has long been that mesenchymal cells at the apex of the vertebrate limb bud proliferate in a progress zone (PZ) under the influence of the apical ectodermal ridge (AER).