Biomedical aspects of pyridoxal 5'-phosphate availability.
Roma, Italy. In Front Biosci (elite Ed), 2011
In humans, PLP is recycled from food and from degraded PLP-dependent enzymes in a salvage pathway requiring the action of pyridoxal kinase, pyridoxine 5'-phosphate oxidase and phosphatases.
Vitamin B(6) salvage enzymes: mechanism, structure and regulation.
Roma, Italy. In Biochim Biophys Acta, 2011
In animals, pyridoxal 5'-phosphate is recycled from food and from degraded B(6)-enzymes in a "salvage pathway", which essentially involves two ubiquitous enzymes: an ATP-dependent pyridoxal kinase and an FMN-dependent pyridoxine 5'-phosphate oxidase.