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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Trace amine associated receptor 5

putative neurotransmitter receptor, TAAR5, GM227, trace amine-associated receptor 5
Top mentioned proteins: GPR58, CAN, GPCR, SIMPLE, TAAR3
Papers on putative neurotransmitter receptor
Trace amine-associated receptors: ligands, neural circuits, and behaviors.
Liberles, Boston, United States. In Curr Opin Neurobiol, Oct 2015
In mouse, TAAR4 and TAAR5 are encoded by adjacent genes and localize to adjacent glomeruli, yet mediate opposing behaviors.
Timberol® Inhibits TAAR5-Mediated Responses to Trimethylamine and Influences the Olfactory Threshold in Humans.
Gisselmann et al., Bochum, Germany. In Plos One, 2014
Human TAAR5 (hTAAR5) is highly expressed in the olfactory mucosa and was shown to be specifically activated by trimethylamine.
Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5.
Biebermann et al., Berlin, Germany. In Plos One, 2014
TAAR5 is a highly conserved TAAR subtype among mammals and we here tested TAAR5 as a potential 3-T1AM target.
Efficient expression and immunoaffinity purification of human trace amine-associated receptor 5 from E. coli cell-free system.
Wang et al., Qingdao, China. In Protein Pept Lett, 2013
Here we report the production of a bioengineered GPCR of human trace amine-associated receptor 5 (hTAAR5) from an E. coli cell-free system.
Synchronous evolution of an odor biosynthesis pathway and behavioral response.
Liberles et al., Boston, United States. In Curr Biol, 2013
RESULTS: Here, we identify a mouse chemosignal, trimethylamine, and its olfactory receptor, trace amine-associated receptor 5 (TAAR5), to be involved in species-specific social communication.
Human trace amine-associated receptor TAAR5 can be activated by trimethylamine.
Gisselmann et al., Bochum, Germany. In Plos One, 2012
We present the first successful functional expression of a human TAAR and agonists of human TAAR5.
Study of two G-protein coupled receptor variants of human trace amine-associated receptor 5.
Zhang et al., Cambridge, United States. In Sci Rep, 2010
Here we report the study of two bioengineered variants of human trace amine-associated receptor 5 (hTAAR5) that were expressed in stable tetracycline-inducible HEK293S cell lines.
G protein-coupled receptor mediated trimethylamine sensing.
Berghard et al., Linköping, Sweden. In Biosens Bioelectron, 2010
The cells were genetically modified to express the mouse trace amine-associated receptor 5 (mTAAR5), a G protein-coupled receptor from the mouse olfactory epithelium, which conferred high sensitivity to TMA.
Structural and functional evolution of the trace amine-associated receptors TAAR3, TAAR4 and TAAR5 in primates.
Schöneberg et al., Leipzig, Germany. In Plos One, 2009
Recently, chemosensory function involving recognition of volatile amines was proposed for murine TAAR3, TAAR4 and TAAR5.
International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature.
Davenport et al., Cambridge, United Kingdom. In Pharmacol Rev, 2009
In humans, a further five genes are thought to encode functional receptors (TAAR2, TAAR5, TAAR6, TAAR8, and TAAR9).
Biogenic Trace Amine-Associated Receptors (TAARS) are encoded in avian genomes: evidence and possible implications.
Kempenaers et al., Starnberg, Germany. In J Hered, 2008
Our results suggest that a minimum of 3 TAAR paralogues are encoded in the G. gallus genome and that these are putative orthologues of the human/mouse genes TAAR1, TAAR2, and TAAR5.
A second class of chemosensory receptors in the olfactory epithelium.
Buck et al., Seattle, United States. In Nature, 2006
Previous studies reported TAAR expression in brain. This paper found TAAR expression only in olfactory epithelial cells and that each TAAR detects a unique set of amine ligands. TAARs seem to function as a family of chemosensory receptors for amines.
A locus for simple pure febrile seizures maps to chromosome 6q22-q24.
LeGuern et al., Paris, France. In Brain, 2002
Sequence analysis excluded the implication of five candidate genes [A kinase anchoring protein 18 (AKAP18), syntaxin 7, putative neurotransmitter receptor (PNR), G protein receptor 57 (GPR57) and G protein receptor 58 (GPR58)] in the interval based on function.
Synthetic glycopeptide-based delivery systems for systemic gene targeting to hepatocytes.
Rolland et al., The Woodlands, United States. In Pharm Res, 2000
or endosomolytic lipopeptide (GM227.3) to obtain DNA particles of 100-150 nm in size.
Cloning and characterization of additional members of the G protein-coupled receptor family.
Marchese et al., Toronto, Canada. In Biochim Biophys Acta, 2000
phBL5, reported only in the patent literature), putative neurotransmitter receptor (PNR) and a 5-HT(4) pseudogene.
Pharmacological agents affecting emesis. A review (Part I).
Mitchelson, Australia. In Drugs, 1992
The availability of radiolabelled ligands selective for various putative neurotransmitter receptor sites and the development of quantitative autoradiography has led to a greater understanding of the neuronal pathway and receptor subtypes involved in the vomiting reflex induced by various mechanisms both within the central nervous system and the periphery.
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