Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinomamore suppliers
In Cell Death & Disease, 1994
... Cell Signaling Technology), anti-Bim (1:500, 559685, BD Transduction Laboratories), anti-Bax (1:500, 554106, BD Transduction Laboratories), anti-PUMA (1:200, sc-28226, Santa Cruz Biotechnology, Santa Cruz, CA, USA), ...
Cell death induced by endoplasmic reticulum stress.
l'Hospitalet de Llobregat, Spain. In Febs J, Dec 2015
These proteins aim to restore homeostasis, but they can also induce cell death, which has been shown to occur by necroptosis and, more commonly, through the regulation of Bcl-2 family proteins (Bim, Noxa and Puma) that leads to mitochondrial apoptosis.
Cisplatin resistance in germ cell tumours: models and mechanisms.
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Hamburg, Germany. In Andrology, 2015
Secondly, GCT, especially embryonal carcinoma (EC) cells, show a hypersensitive apoptotic response to DNA damage, which activates p53, and leads to up-regulation of the pro-apoptotic factors Noxa, Puma and Fas in non-resistant EC.
The Toxicity of Poisons Applied Jointly
In Cell Death & Disease, 1938
... For Dox-inducible, stable expression in J16 cells, HA-tagged Bid, Bim, Noxa and Puma cDNA′s were cloned into the lentiviral vector pLVX-Tight (Clontech, Mountain View, CA, USA) ...