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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Pituitary tumor-transforming 2

PTTG2
Top mentioned proteins: PTTG, separase, E-cadherin, vimentin, p53
Papers on PTTG2
Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression.
Yang et al., China. In Int J Clin Exp Pathol, 2014
This study focused on the roles of pituitary tumor transforming gene 2 (PTTG2) in psoriasis.
Critical differences between isoforms of securin reveal mechanisms of separase regulation.
Poon et al., Hong Kong, Hong Kong. In Mol Cell Biol, 2013
Remarkably, a highly homologous isoform called PTTG2 was unable to interact with separase.
[Whole-genome messenger RNA profiling reveals genes involved in malignant progression of glioma].
Jiang et al., Beijing, China. In Zhonghua Yi Xue Za Zhi, 2013
Microarray data were validated by immunohistochemistry. RESULTS: Among all the detected genes, the genes up-regulated mostly in high-grade glioma were IGFBP-2, CKLF, PTTG1, OSTCL and PTTG2 while those down-regulated mostly SEC31, RRP7B, HOOK3, SNRPN and CSMD3.
PTTG2 silencing results in induction of epithelial-to-mesenchymal transition and apoptosis.
Pintor-Toro et al., Sevilla, Spain. In Cell Death Dis, 2012
Two homologous genes, pttg2 and pttg3, have been identified although very little is known about their physiological function.
Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo.
Im et al., Taej┼Ćn, South Korea. In Hepatology, 2006
We report that PTTG1, but not PTTG2 and 3, was highly and frequently expressed in liver cancer tissues from patients and highly in SH-J1, SK-Hep1, and Huh-7 hepatoma cell lines.
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