Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data.
Philadelphia, United States. In Circ Res, 2014
encompassing CYFIP1, NIPA1, and NIPA2 and single de novo CNVs encompassing DUSP1, JUN, JUP, MED15, MED9, PTPRE SREBF1, TOP2A, and ZEB2, genes that interact with established CHD proteins NKX2-5 and GATA4.
Protein tyrosine phosphatases in osteoclasts.
Israel. In Crit Rev Eukaryot Gene Expr, 2006
We review here the roles of the four tyrosine phosphatases that are known currently to be expressed in osteoclasts--PTPRO, PTP epsilon (PTPepsilon), SHP-1, and PTP-PEST.
Regulation of cys-based protein tyrosine phosphatases via reactive oxygen and nitrogen species in mast cells and basophils.
Praha, Czech Republic. In Curr Med Chem, 2004
Direct and indirect regulations of class I and II Cys-based protein tyrosine phosphatases (LMW-PTP, PTEN, PTP-PEST, SHP-2, PTP1B, PTPalpha, PTPepsilon, DEP-1, TC45, SHP-1, HePTP and LAR) are discussed.