Characterization of synthetic human granulocyte chemotactic protein 2: usage of chemokine receptors CXCR1 and CXCR2 and in vivo inflammatory properties
In The EMBO Journal, 1996
... CD87 (VIM5, BD), CD88 (S5/1, Biolegend), CD89 (Mip8a, Abd-Serotec), CD114 (LMM741, BD), CD119 (GIR-208, BD), CD162 (KPL-1, BD), CD181 (42705.111,
Central nervous system niche involvement in the leukemia.
Ahvāz, Iran. In Clin Transl Oncol, Sep 2015
Given the importance of prognosis and early diagnosis of CNS involvement in leukemias as well as the severe side effects of current treatments, diagnostic and therapeutic approaches should focus on identification and inhibition of the factors contributing to CNS involvement, including CXCR3, P-selectin glycoprotein ligand-1 and MCP1.
[Research advances on ADAM28 expression and ADAM28-mediated tumor metastasis].
Beijing, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2014
ADAM28-mediated cancer cell metastasis may be related with the cleavage of von Willebrand's factor (vWF), insulin-like growth factor binding protein-3 (IGFBP-3) and connective tissue growth factor (CTGF), as well as the promoting PSGL-1/P-selectin-mediated cell adhesion.
Activation states of blood eosinophils in asthma.
Madison, United States. In Clin Exp Allergy, 2014
A number of eosinophil surface proteins, including CD69, L-selectin, intercellular adhesion molecule-1 (ICAM-1, CD54), CD44, P-selectin glycoprotein ligand-1 (PSGL-1, CD162), cytokine receptors, Fc receptors, integrins including αM integrin (CD11b), and activated conformations of Fc receptors and integrins, have been proposed to report cell activation.
Cell and tissue tropism of enterovirus 71 and other enteroviruses infections.
Taiwan. In J Biomed Sci, 2013
SCARB2 or PSGL-1 receptor binding is the first step in the development of viral infections, and viral factors (e.g., 5' UTR, VP1, 3C, 3D, 3' UTR), host factors and environments (e.g., ITAFs, type I IFN) are also involved in viral infections.
'Slings' enable neutrophil rolling at high shear.
Los Angeles, United States. In Nature, 2012
We demonstrate slings in a model of acute inflammation in vivo and on P-selectin in vitro, where P-selectin-glycoprotein-ligand-1 (PSGL-1) is found in discrete sticky patches whereas LFA-1 is expressed over the entire length on slings.
A role for leukocyte-endothelial adhesion mechanisms in epilepsy.
In Nat Med, 2008
Using a mouse model of epilepsy, we show that seizures induce elevated expression of vascular cell adhesion molecules and enhanced leukocyte rolling and arrest in brain vessels mediated by the leukocyte mucin P-selectin glycoprotein ligand-1 (PSGL-1, encoded by Selplg) and leukocyte integrins alpha(4)beta(1) and alpha(L)beta(2).