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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Pregnancy specific beta-1-glycoprotein 9

PSG11, Pregnancy-specific glycoprotein, PSG9, PSG13, pregnancy-specific glycoprotein 5
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009] (from NCBI)
Top mentioned proteins: CD45, PSG, CEA, PSG6, ACID
Papers on PSG11
Recombinant N-Domain of Pregnancy-Specific Glycoprotein from E. coli Cells: Analysis of the Spectrum of Polyclonal Antibodies.
Terent'ev et al., Moscow, Russia. In Bull Exp Biol Med, Nov 2015
We studied antibody spectrum in antisera to IgG-like recombinant N-domain of pregnancyspecific glycoprotein-1 (rPSG-N) from E. coli cells.
Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-β and prevents dextran sodium sulfate (DSS)-induced colitis in mice.
Dveksler et al., Berlin, Germany. In Mucosal Immunol, 2014
Transforming growth factor-βs (TGF-βs) are secreted from cells as latent complexes and the activity of TGF-βs is controlled predominantly through activation of these complexes.
Integrative network analysis of TCGA data for ovarian cancer.
Wang et al., Evanston, United States. In Bmc Syst Biol, 2013
In addition, two genes related to glycoprotein synthesis, PSG11 and GALNT10, were found highly predictive for the overall survival time of ovarian cancer patients.
Pregnancy-specific glycoproteins: complex gene families regulating maternal-fetal interactions.
Dveksler et al., Cork, Ireland. In Int J Dev Biol, 2013
There are ten protein-coding human PSG genes (PSG1 - PSG9, PSG11) and also multiple PSG genes in non-human primates, rodents and bats.
Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.
Moore et al., Cork, Ireland. In Plos One, 2012
Human PSG9 and mouse Psg23 are also inhibitory suggesting conservation of this function across primate and rodent PSG families.
Pregnancy-specific glycoprotein 1a activates dendritic cells to provide signals for Th17-, Th2-, and Treg-cell polarization.
Motrán et al., Córdoba, Argentina. In Eur J Immunol, 2012
Here, we show that pregnancy-specific glycoprotein (PSG1a), the major variant of PSG released into the circulation during pregnancy, targets DCs to differentiate into a subset with a unique phenotype and function.
Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients.
Dewan et al., New Haven, United States. In Bmc Pregnancy Childbirth, 2011
(5/169 cases and 1/114 controls), which encompasses the PSG11 gene contiguous to a highly plastic genomic region.
Pregnancy-specific glycoprotein 1 induces endothelial tubulogenesis through interaction with cell surface proteoglycans.
Dveksler et al., Bethesda, United States. In J Biol Chem, 2011
Pregnancy-specific β1 glycoproteins (PSGs) are the most abundant fetal proteins in the maternal bloodstream in late pregnancy.
Expression and transcriptional regulation of individual pregnancy-specific glycoprotein genes in differentiating trophoblast cells.
Panzetta-Dutari et al., Córdoba, Argentina. In Placenta, 2010
Among them, PSG1, PSG3 and PSG5 genes achieve high mRNA levels while PSG7 and PSG9 are poorly expressed.
RXRalpha regulates the pregnancy-specific glycoprotein 5 gene transcription through a functional retinoic acid responsive element.
Bocco et al., Córdoba, Argentina. In Placenta, 2007
Human pregnancy-specific glycoproteins (PSG) are major placental polypeptides encoded by eleven highly conserved genes expressed by the syncytiotrophoblast.
Differential gene expression profile reveals deregulation of pregnancy specific beta1 glycoprotein 9 early during colorectal carcinogenesis.
Woodgett et al., Toronto, Canada. In Bmc Cancer, 2004
PSG9 may have a role in development of colorectal carcinogenesis in patients with adenomatous polyposis coli
Transcriptional control of the human pregnancy-specific glycoprotein 5 gene is dependent on two GT-boxes recognized by the ubiquitous specificity protein 1 (Sp1) transcription factor.
Panzetta-Dutari et al., Córdoba, Argentina. In Placenta, 2004
Pregnancy-specific glycoprotein 5 gene (PSG-5) belongs to the human pregnancy-specific glycoprotein family, encoded by eleven highly similar and transcriptionally active genes.
Pregnancy-specific glycoproteins function as immunomodulators by inducing secretion of IL-10, IL-6 and TGF-beta1 by human monocytes.
Dveksler et al., Bethesda, United States. In Am J Reprod Immunol, 2001
METHOD OF STUDY: Human monocytes and murine RAW 264.7 cells were treated with recombinant PSG1, PSG6, PSG11, or a truncated PSG6 consisting of only the N-terminal domain (PSG6N).
Pregnancy-specific glycoprotein (PSG) in baboon (Papio hamadryas): family size, domain structure, and prediction of a functional region in primate PSGs.
Hammarström et al., Umeå, Sweden. In Biol Reprod, 2001
Pregnancy-specific glycoprotein (PSG) constitutes a major component of serum of pregnant women and appears to be essential for a successful pregnancy.
Evolution of the carcinoembryonic antigen family. structures of CGM9, CGM11 and pregnancy-specific glycoprotein promoters.
Hammarström et al., Umeå, Sweden. In Tumour Biol, 2000
Earlier studies have demonstrated that the genes of the human carcinoembryonic antigen (CEA) family can be divided into three subgroups, the CEA subgroup (n = 12), the pregnancy-specific glycoprotein (PSG) subgroup (n = 11), and a third subgroup (n = 6).
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