mRNA Profiling Reveals Determinants of Trastuzumab Efficiency in HER2-Positive Breast Cancer.
Göttingen, Germany. In Plos One, Dec 2014
GDF15, IL8, LCN2, PTGS2 and 20 other genes were significantly higher expressed in HCC1954 than in BT474, while NCAM2, COLEC12, AFF3, TFF3, NRCAM, GREB1 and TFF1 were significantly lower expressed.
Pomegranate fruit as a rich source of biologically active compounds.
Thiruvananthapuram, India. In Biomed Res Int, 2013
In this review, we have mainly focused on the already published data from our laboratory pertaining to the effect of methanol extract of pericarp of pomegranate (PME) and have compared it with other relevant literatures on Punica.
The genetics of Alzheimer's disease.
South Korea. In Clin Interv Aging, 2013
Three main genes are involved in early onset AD: amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2).
Role of BRI2 in dementia.
Amsterdam, Netherlands. In J Alzheimers Dis, 2013
Whereas the etiology of sporadic AD remains unclear, familial AD is linked to mutations in amyloid-β protein precursor (AβPP), presenilin 1 (PS1), and presenilin 2 (PS2).
[Familial Alzheimer disease].
Tokyo, Japan. In Nihon Rinsho, 2011
Current findings established the involvement of APP, PS1, and PS2 in familial case of Alzheimer disease, while APO polymorphism suggests the existence of other unknown genetic factors or risk factors in the cause of this disease.
Transient cyclical methylation of promoter DNA.
Heidelberg, Germany. In Nature, 2008
We reported previously that the proximal region of the trefoil factor 1 (TFF1, also known as pS2) and oestrogen receptor alpha (ERalpha) promoters could be partially methylated by treatment with deacetylase inhibitors, suggesting the possibility of dynamic changes in DNA methylation.