Bi-level Positive Airway Pressure (BiPAP) with standard exhalation valve does not improve maximum exercise capacity in patients with COPD.
Montréal, Canada. In Copd, Feb 2015
METHODS: Peak exercise workload (WLpeak), dyspnea (Borg), end-expiratory lung volume (EELV), tidal volume (VT), minute ventilation (VE), O2 uptake (VO2), and CO2 production (VCO2) were assessed in 10 COPD patients (FEV1 53 ± 22% pred) during three symptom-limited bicycle exercise tests while breathing i) without a ventilator (noPS), ii) with a pressure support (PS) of 0 cm H2O (PS0; IPAP & EPAP 4 cm H2O) and iii) PS of 10 cm H2O (PS10; IPAP 14 & EPAP 4 cm H2O) on separate days using a randomized crossover design.
Transient ordered domains in single-component phospholipid bilayers.
Espoo, Finland. In Phys Rev Lett, 2007
In addition, our simulations suggest that domains of lipids with highly ordered acyl chains form predominantly within the dense regions, their sizes ranging from a few chains up to a few nanometers, and with lifetimes between approximately 10 ps-10 ns.