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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

PRP43 Prp43p

Prp43, Prp43p, DBP1, DDX15
The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, ATPase, Dbp, Prp22, PRP16
Papers on Prp43
Limited portability of G-patch domains in regulators of the Prp43 RNA helicase required for pre-mRNA splicing and ribosomal RNA maturation in Saccharomyces cerevisiae.
New
Rymond et al., Lexington, United States. In Genetics, May 2015
The Prp43 DExD/H-box protein is required for progression of the biochemically distinct pre-messenger RNA and ribosomal RNA (rRNA) maturation pathways.
The telomerase inhibitor Gno1p/PINX1 activates the helicase Prp43p during ribosome biogenesis.
Henry et al., Toulouse, France. In Nucleic Acids Res, 2014
Moreover, PINX1 interacts with human PRP43 (DHX15) in HeLa cells.
Identification of a novel aminopropyltransferase involved in the synthesis of branched-chain polyamines in hyperthermophiles.
Fujiwara et al., Sanda, Japan. In J Bacteriol, 2014
Compared to the wild type, the bpsA-disrupted strain DBP1 grew at 85°C with a slightly longer lag phase but was unable to grow at 93°C.
Arabidopsis protein phosphatase DBP1 nucleates a protein network with a role in regulating plant defense.
Vera et al., Valencia, Spain. In Plos One, 2013
Arabidopsis thaliana DBP1 belongs to the plant-specific family of DNA-binding protein phosphatases.
Responses to booster hepatitis B vaccination are significantly correlated with genotypes of human leukocyte antigen (HLA)-DPB1 in neonatally vaccinated adolescents.
Wang et al., Taipei, Taiwan. In Hum Genet, 2013
HLA-DBP1 may also determine the long-term persistence of response to HB vaccination.
Genomic and molecular aberrations in malignant peripheral nerve sheath tumor and their roles in personalized target therapy.
Review
Du et al., Tianjin, China. In Surg Oncol, 2013
The involved genes in the significant gains aberrations include BIRC5, CCNE2, DAB2, DDX15, EGFR, DAB2, MSH2, CDK6, HGF, ITGB4, KCNK12, LAMA3, LOXL2, MET, and PDGFRA.
Genome-wide association study of serum albumin:globulin ratio in Korean populations.
Kim et al., South Korea. In J Hum Genet, 2013
Eleven SNPs from six loci (GALNT2, IRF4, HLA-DBP1, SLC31A1, FADS1 and TNFRSF13B) were replicated, with P-values<0.05.
RNA-interacting proteins act as site-specific repressors of ADAR2-mediated RNA editing and fluctuate upon neuronal stimulation.
Jantsch et al., Vienna, Austria. In Nucleic Acids Res, 2013
The three proteins RPS14, SFRS9 and DDX15 interact with RNA.
Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity.
GeneRIF
Li et al., Beijing, China. In Febs Lett, 2012
Data suggest that G-patch domain of RBM5 is indispensable for its ability to interact with DHX15; RBM5 stimulates helicase activity of DHX15 in a G-patch domain-dependent manner.
A plant small polypeptide is a novel component of DNA-binding protein phosphatase 1-mediated resistance to plum pox virus in Arabidopsis.
Vera et al., Valencia, Spain. In Plant Physiol, 2011
Here, we report on the identification of a novel family of highly conserved small polypeptides that interact with DBP1 proteins both in tobacco and Arabidopsis, which we have designated DBP-interacting protein 2 (DIP2).
The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing.
GeneRIF
Staley et al., Chicago, United States. In Mol Cell, 2010
The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing.
Spliceosome discards intermediates via the DEAH box ATPase Prp43p.
GeneRIF
Staley et al., Chicago, United States. In Proc Natl Acad Sci U S A, 2010
Prp43p promotes the discard of suboptimal and optimal 5' exon and lariat intermediates indiscriminately.
Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly.
Paine et al., Los Angeles, United States. In Biochem Biophys Res Commun, 2010
Tuftelin-interacting protein 11 (TFIP11) is a protein component of the spliceosome complex that promotes the release of the lariat-intron during late-stage splicing through a direct recruitment and interaction with DHX15/PRP43.
The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis.
GeneRIF
Henry et al., Toulouse, France. In Embo J, 2010
stimulation of ATPase/helicase activities of Prp43p by Pfa1p is required for efficient 20S pre-rRNA-to-18S rRNA conversion
Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis.
GeneRIF
Tollervey et al., Edinburgh, United Kingdom. In Mol Cell, 2009
Prp43 acts on preribosomal regions surrounding each binding site, with distinct functions at different locations.
Inhibition of a spliceosome turnover pathway suppresses splicing defects.
Rymond et al., Lexington, United States. In Proc Natl Acad Sci U S A, 2006
Stringent proteomic and two-hybrid analyses show that Spp382p also interacts with Cwc23p, a DNA J-like protein present in the spliceosome and copurified with the Prp43p DExD/H-box ATPase.
14-3-3 mediates transcriptional regulation by modulating nucleocytoplasmic shuttling of tobacco DNA-binding protein phosphatase-1.
Vera et al., Valencia, Spain. In J Biol Chem, 2006
Tobacco DBP1 is the founding member of a novel class of plant transcription factors featuring sequence-specific DNA binding and protein phosphatase activity.
Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.
GeneRIF
Beggs et al., Edinburgh, United Kingdom. In Mol Cell Biol, 2006
Ntr1 promotes release of excised introns from splicing complexes by acting as a spliceosome receptor or RNA-targeting factor for Prp43, possibly assisted by the Ntr2 protein.
Mutations in PRP43 that uncouple RNA-dependent NTPase activity and pre-mRNA splicing function.
GeneRIF
Schwer et al., New York City, United States. In Biochemistry, 2006
We report that Prp43 hydrolyzes all common NTPs and dNTPs and unwinds short 5'/3' tailed RNA/DNA duplexes in an ATP-dependent fashion.
Chromosomal imbalances in malignant peripheral nerve sheath tumor detected by metaphase and microarray comparative genomic hybridization.
Ozaki et al., Okayama, Japan. In Oncol Rep, 2006
Microarray CGH revealed frequent gains of EGFR, DAB2, MSH2, KCNK12, DDX15, CDK6, and LAMA3, and losses of CDH1, GLTSCR2, EGR1, CTSB, GATA3, and SULT2A1.
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