The many shades of prion strain adaptation.
Baltimore, United States. In Prion, 11 Mar 2014
UNLABELLED: In several recent studies transmissible prion disease was induced in animals by inoculation with recombinant prion protein amyloid fibrils produced in vitro.
Inflammasomes in the CNS.
Edmonton, Canada. In Nat Rev Neurosci, 28 Feb 2014
Assembly of an inflammasome activates caspase 1 and, subsequently, the proteolysis and release of the cytokines interleukin-1β and interleukin-18, as well as pyroptotic cell death.
Pyroptotic death storms and cytopenia.
Boston, United States. In Curr Opin Immunol, 28 Feb 2014
In this review, we will focus on the biochemical and cellular mechanisms controlling pyroptosis, a Caspase-1/11 dependent form of cell death during infection.
Update on creutzfeldt-jakob disease.
More papers using
Melbourne, Australia. In Pathology, 28 Feb 2014
Creutzfeldt-Jakob disease (CJD) is a transmissible spongiform encephalopathy caused by the accumulation of an abnormal conformer of the prion protein (PrP).