Inflammasome control of viral infection.
Memphis, United States. In Curr Opin Virol, 12 Apr 2015
UNASSIGNED: The inflammasome is a caspase-1 containing complex that activates the proinflammatory cytokines IL-1β and IL-18 and results in the proinflammatory cell death known as pyroptosis.
A RecA Protein Surface Required for Activation of DNA Polymerase V.
Bethesda, United States. In Plos Genet, 28 Feb 2015
The same RecA surface is not utilized in the RecA activation of the homologous and highly mutagenic RumA'2B polymerase encoded by the integrating-conjugative element (ICE) R391, indicating a lack of structural conservation between the two systems.
Biochemical insight into the prion protein family.
Jouy-le-Moutier, France. In Front Cell Dev Biol, Dec 2014
Finally, we questioned if prion protein family have conserved the PrP structural bistability, which should be at the origin of Prion phenomenon and if Prion pathology is not, ultimately, an exaptation of the physiological propensity of PrP to undergo a structural switch and polymerize.
Gut-liver axis: role of inflammasomes.
India. In J Clin Exp Hepatol, 2013
They are involved in recognizing diverse microbial (bacteria, viruses, fungi and parasites), stress and damage signals, which result in direct activation of caspase-1, leading to secretion of potent pro-inflammatory cytokines and pyroptosis.
Prevention of carcinogenesis and cancer metastasis by bovine lactoferrin.
More papers using
Nagoya, Japan. In Proc Jpn Acad Ser B Phys Biol Sci, 2006
The mechanisms are wide-spectrum, including elevation of caspase-1 and IL-18 in the small intestine, enhancement of the cell killing activity of cytotoxic T and natural killer (NK) cells, and anti-inflammatory and anti-angiogenic effects.