Necroptosis, in vivo detection in experimental disease models.
Gent, Belgium. In Semin Cell Dev Biol, Sep 2014
Initially, Receptor-Interacting Protein Kinase 1 (RIPK1) and RIPK3 kinase activity were uniquely associated with induction of necroptosis, however recent evidence suggests pleiotropic functions in cell death, inflammation and survival, obscuring a clear picture.
Metabolism of activated T lymphocytes.
Saskatoon, Canada. In Curr Opin Immunol, Apr 2014
In contrast, T regulatory (Treg) cells are generated when AMP-Activating Protein Kinase signaling is activated and mTOR activation is suppressed.