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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 28 Aug 2015.

Casein kinase 1, delta

Protein Kinase
Top mentioned proteins: CAN, MAPK, V1a, Akt, ACID
Papers on Protein Kinase
Snf1 Phosphorylates Adenylate Cyclase and Negatively Regulates Protein Kinase A-dependent Transcription in Saccharomyces cerevisiae.
New
Coccetti et al., Milano, Italy. In J Biol Chem, 26 Sep 2015
In yeast, Protein Kinase A (PKA) is activated in the presence of high glucose concentrations, favoring fast nutrient utilization, shutting down stress responses and boosting growth.
Protein Kinase-A inhibition is sufficient to support human neural stem cells self-renewal.
New
Benchoua et al., France. In Stem Cells, 24 Sep 2015
We analyzed 80 small molecules acting as kinase inhibitors and identified compounds of the 5-isoquinolinesulfonamide family, described as Protein Kinase A and Protein Kinase G inhibitors, as candidates to support hNSC self-renewal.
Lack of Evidence for PKM2 Protein Kinase Activity.
New
Vander Heiden et al., Cambridge, United States. In Mol Cell, 19 Sep 2015
A unique function of PKM2 proposed to be important for the proliferation of some cancer cells involves the direct activity of this enzyme as a protein kinase; however, a detailed biochemical characterization of this activity is lacking.
Is 5´-AMP-Activated Protein Kinase Both Jekyll and Hyde in Bladder Cancer?
Review
New
Kim, Ch'ŏngju, South Korea. In Int Neurourol J, Jun 2015
The 5´-AMP-activated protein kinase (AMPK) is a key regulator of cellular metabolism and energy homeostasis in mammalian tissues.
Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications.
Review
New
Abriel et al., Nantes, France. In J Mol Cell Cardiol, May 2015
In this review, we examine the recent literature demonstrating glycosylation, phosphorylation by Protein Kinases A and C, Ca(2+)/Calmodulin-dependent protein Kinase II, Phosphatidylinositol 3-Kinase, Serum- and Glucocorticoid-inducible Kinases, Fyn and Adenosine Monophosphate-activated Protein Kinase, methylation, acetylation, redox modifications, and ubiquitylation of Na(V)1.5.
Pin1: Intimate Involvement with the Regulatory Protein Kinase Networks in the Global Phosphorylation Landscape.
Review
New
Gyenis et al., London, Canada. In Biochim Biophys Acta, Apr 2015
MAJOR CONCLUSIONS: The relationship between Pin1 and the regulatory protein kinase networks is not restricted simply to the recognition of proteins that are substrates for proline-directed kinases.
Staurosporine Induces Platelet Apoptosis Through p38 Mitogen-Activated Protein Kinase Signaling Pathway.
New
Dai et al., In Clin Lab, Dec 2014
Furthermore, STS stimulation induced phosphorylation of p38 mitogen-activated protein kinase (MAPK).
Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK.
New
Gaestel et al., Hannover, Germany. In Plos One, Dec 2014
MK5 (MAPK-activated protein kinase 5) or PRAK (p38-regulated and -activated kinase) are alternative names for a serine/threonine protein kinase downstream to ERK3/4 and p38 MAPK.
Targeting Protein Kinase C Downstream of Growth Factor and Adhesion Signalling.
Review
New
Kiely et al., Limerick, Ireland. In Cancers (basel), Dec 2014
One of the key groups of proteins required to regulate these activities is the family of serine/threonine intracellular kinases called Protein Kinase Cs.
The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control.
Review
New
Hall et al., Basel, Switzerland. In Cold Spring Harb Perspect Biol, Dec 2014
Although target of rapamycin (TOR) is a major promoter of growth in response to nutrients and growth factors, AMP-activated protein kinase (AMPK) suppresses anabolic processes in response to energy stress.
Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease.
New
Hannun et al., Sendai, Japan. In Plos One, Dec 2014
UNASSIGNED: Gaucher's disease is caused by defects in acid β-glucosidase 1 (GBA1) and has been also proposed as an inflammatory disease.
Drosophila and vertebrate casein kinase Idelta exhibits evolutionary conservation of circadian function.
GeneRIF
Price et al., Kansas City, United States. In Genetics, 2009
The results demonstrate a high degree of evolutionary conservation of fly and vertebrate CKIdelta and of the functions affected by their period-shortening mutations.
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction.
Impact
Tomlinson et al., New York City, United States. In Nat Cell Biol, 2005
Together, Protein Kinase A, Casein Kinase 1 and Glycogen Synthase Kinase 3 silence the pathway in the absence of ligand by phosphorylating Ci at a defined cluster of sites, thereby promoting its proteolytic conversion to a transcriptional repressor (Ci-75).
Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.
Impact
Kalderon et al., New York City, United States. In Cell, 2002
Ci-155 proteolysis depends on phosphorylation at three sites by Protein Kinase A (PKA).
Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network.
Impact
Malhotra et al., San Diego, United States. In Cell, 2001
When a kinase inactive form of Protein Kinase D (PKD-K618N) was expressed in HeLa cells, it localized to the trans-Golgi network (TGN) and caused extensive tubulation.
Analogs of cyclic adenosine monophosphate: correlation of inhibition of Purkinje Neurons with Protein Kinase Activation.
Impact
Henriksen et al., In Science, 1975
with their reported potency in activating cyclic AMP-dependent protein kinase.
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