GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 17 Jun 2013.
Casein kinase 1, delta
Protein Kinase
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Papers on
Protein Kinase
Induction of Vascular Insulin Resistance, Endothelin-1 Expression, and Acceleration of Atherosclerosis by the Overexpression of Protein Kinase C β Isoform in the Endothelium.
New
Boston, United States. In Circ Res, 11 Jul 2013
Hyperglycemia and elevated fatty acids induced by diabetes can activate protein kinase C (PKC) β isoforms and selectively inhibit insulin signaling via phosphatidylinositol 3-kinase (PI3K)/Akt pathway to inhibit the activation of endothelial nitric oxide synthase (eNOS) and metabolic actions.
Cell cycle and apoptosis regulatory protein (CARP)-1 is expressed in osteoblasts and regulated by pth.
New
Detroit, United States. In Biochem Biophys Res Commun, 10 Jul 2013
H-89, a Protein Kinase A (PKA) inhibitor, suppressed PTH action on CARP-1 protein expression indicating PKA-dependent mechanism.
AMP-Activated Protein Kinase Signaling Protects Oligodendrocytes that Restore Central Nervous System Functions in an Experimental Autoimmune Encephalomyelitis Model.
New
Charleston, United States. In Am J Pathol, 08 Jul 2013
AMP-activated protein kinase (AMPK) signaling is reported to protect neurons under pathologic conditions; however, its effect on oligodendrocytes (OLs) remains to be elucidated.
Regulation of miRNA biogenesis as an integrated component of growth factor signaling.
Review
New
San Francisco, United States. In Curr Opin Cell Biol, Apr 2013
In this article we use well-characterized growth-factor signaling pathways such as transforming growth factor-β (TGF-β), Protein Kinase B (PKB, also known as Akt) and extracellular-signal-regulated kinase (ERK) to illustrate how basic cell signaling pathways modulate the activities of these components of the miRNA biogenesis pathway to achieve optimal miRNA expression patterns.
cGMP-Dependent Protein Kinase Iβ Interacts with p44/WDR77 to Regulate Androgen Receptor-Driven Gene Expression.
New
Houston, United States. In Plos One, Dec 2012
To further elucidate p44/WDR77's role in the AR signaling pathway, we conducted a yeast two-hybrid screening and identified cGMP-dependent protein kinase (PKG) as a p44/WDR77-interacting protein.
Current and future trials of targeted therapies in cutaneous melanoma.
Review
New
Penn Hills, United States. In Adv Exp Med Biol, Dec 2012
The Mitogen Activated Protein Kinase (MAPK) pathway has been identified as a key player in melanoma development making this cascade an important therapeutic target.
The C-terminal v5 domain of protein kinase cα is intrinsically disordered, with propensity to associate with a membrane mimetic.
New
College Station, United States. In Plos One, Dec 2012
The C-terminal V5 domain is one of the most variable domains in Protein Kinase C isoforms (PKCs).
Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology.
Review
New
Durham, United States. In J Biol Chem, Oct 2012
CaMKK2 is one of the most versatile of the CaMKs and will phosphorylate and activate CaMKI, CaMKIV, and AMP-activated protein kinase.
AMP-activated protein kinase in the control of cardiac metabolism and remodeling.
Review
New
Brussels, Belgium. In Curr Heart Fail Rep, Sep 2012
The AMP-activated protein kinase (AMPK) can be firstly considered as a cellular fuel gauge.
Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a.
New
Impact
Kyoto, Japan. In Cell Stem Cell, Jul 2012
Activation of protein kinase A (PKA) modulates differentiation timing to accelerate the appearance of mesoderm and other germ layer cells, reciprocally correlated with the earlier disappearance of pluripotent markers after ESC differentiation.
Protein kinase C-theta inhibitors: a novel therapy for inflammatory disorders.
Review
Patiāla, India. In Curr Pharm Des, 2011
PKC-θ is a serine/threonine specific protein kinase and its activation depends upon the concentration of diacylglycerol (DAG) and phospholipids (phosphatidylserine). PKC-θ phosphorylates a variety of proteins that are known to be involved in the diverse cellular signaling pathways.
Drosophila and vertebrate casein kinase Idelta exhibits evolutionary conservation of circadian function.
GeneRIF
Kansas City, United States. In Genetics, 2009
The results demonstrate a high degree of evolutionary conservation of fly and vertebrate CKIdelta and of the functions affected by their period-shortening mutations.
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction.
Impact
New York City, United States. In Nat Cell Biol, 2005
Together, Protein Kinase A, Casein Kinase 1 and Glycogen Synthase Kinase 3 silence the pathway in the absence of ligand by phosphorylating Ci at a defined cluster of sites, thereby promoting its proteolytic conversion to a transcriptional repressor (Ci-75).
Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.
Impact
New York City, United States. In Cell, 2002
Ci-155 proteolysis depends on phosphorylation at three sites by Protein Kinase A (PKA).
Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network.
Impact
San Diego, United States. In Cell, 2001
When a kinase inactive form of Protein Kinase D (PKD-K618N) was expressed in HeLa cells, it localized to the trans-Golgi network (TGN) and caused extensive tubulation.
Analogs of cyclic adenosine monophosphate: correlation of inhibition of Purkinje Neurons with Protein Kinase Activation.
Impact
In Science, 1975
with their reported potency in activating cyclic AMP-dependent protein kinase.
