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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 26 Nov 2014.

Prolactin

Prolactin, PRL
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: HAD, CAN, AGE, Insulin, fibrillin-1
Papers using Prolactin antibodies
The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.
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Korach Kenneth S. et al., In Environmental Health Perspectives, 2009
... including 0.2 μg of expression plasmid, 0.2 μg of reporter plasmid, and 0.1 μg of pRL-TK plasmid, were transfected overnight using Effectene Transfection Reagent (QIAGEN, Valencia, CA) according to ...
Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus.
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Ratner Adam J., In PLoS ONE, 2007
... Plasmids pCRE-Luc and pRL-TK were obtained from Clontech and Promega, respectively ...
Cell dynamics and immune response to BLV infection: a unifying model.
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Kehn-Hall Kylene, In PLoS ONE, 2006
... The plasmid expressing the Renilla luciferase via the enhancerless promoter pRL-null (pRL-renilla) was purchased from Promega Corporation (Madison WI, USA) ...
Increase in bone mineral density of patients with rheumatoid arthritis treated with anti-TNF-alpha antibody: a prospective open-label pilot study
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Nanes Mark S et al., In Journal of Bone and Mineral Research, 2004
... ) The Dual Luciferase Assay System, TNF T7 Coupled Reticulocyte Lysate System, and pRL-TK control vector were purchased from Promega Corporation (Madison, WI, USA) ...
A statistical model for identifying proteins by tandem mass spectrometry
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Zhu Jianhong et al., In Proteome Science, 2002
... Tris-Buffered Saline (TBS) for 4 min and then incubated at 1:300 dilution of primary anti-rabbit polyclonal prolactin antibody (Dako Cytomation, Copenhagen, Denmark) in ...
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Papers on Prolactin
Retrospective comparison of cabergoline and bromocriptine effects in hyperprolactinemia: a single center experience.
New
Guler et al., Bethesda, United States. In J Endocrinol Invest, 25 Dec 2014
In most cases, DAs normalize prolactin levels, control symptoms, and substantially decrease tumor size.
The effect of chronic stress on prenatal development of the central nervous system.
New
Romanini et al., Río Cuarto, Argentina. In Biotech Histochem, 25 Dec 2014
These changes were related to decreased prolactin and increased corticosterone concentrations in the plasma.
Evaluation of ovarian function and metabolic factors in women affected by polycystic ovary syndrome after treatment with D-Chiro-Inositol.
New
Pizzo et al., Messina, Italy. In Arch Gynecol Obstet, 22 Dec 2014
We analyzed pre-treatment and post-treatment BMI, Systolic and Diastolic blood pressure, Ferriman-Gallwey score, Cremoncini score, serum LH, LH/FSH ratio, total and free testosterone, DHEA-S, Δ-4-androstenedione, SHBG, prolactin, glucose/IRI ratio, HOMA index, and resumption of regular menstrual cycles.
Gender and magnetic resonance imaging classification-related differences in clinical and biochemical characteristics of Cushing's disease: a single-centre study.
New
Sun et al., Shanghai, China. In Chin Med J (engl), 30 Nov 2014
Hyper-TC levels and PRL reduction were more frequent in males (P < 0.05).
The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus.
New
Impact
Luckman et al., Ann Arbor, United States. In Cell Metab, 07 Nov 2014
Leptin is a critical regulator of metabolism, which acts on brain receptors (Lepr) to reduce energy intake and increase energy expenditure.
Inclusion of endogenous hormone levels in risk prediction models of postmenopausal breast cancer.
New
Impact
Hankinson et al., Boston, United States. In J Clin Oncol, 01 Nov 2014
Therefore, we evaluated whether inclusion of plasma estradiol, estrone, estrone sulfate, testosterone, dehydroepiandrosterone sulfate, prolactin, and sex hormone-binding globulin (SHBG) improved risk prediction for postmenopausal invasive breast cancer (n = 437 patient cases and n = 775 controls not using postmenopausal hormones) in the Nurses' Health Study.
Neonatal screening and a new cause of congenital central hypothyroidism.
Review
New
Ishizu et al., Sapporo, Japan. In Ann Pediatr Endocrinol Metab, Sep 2014
In addition, approximately 60% of patients also suffer a prolactin deficiency.
Pseudocyesis, delusional pregnancy, and psychosis: The birth of a delusion.
Review
New
Seeman, Toronto, Canada. In World J Clin Cases, Sep 2014
When antipsychotic medication was used to treat psychotic symptoms in these women, it led to high prolactin levels and apparent manifestations of pregnancy, such as amenorrhea and galactorrhea, thus reinforcing a false conviction of pregnancy.
PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin.
New
Impact
Struman et al., Liège, Belgium. In Nat Med, Jul 2014
The N-terminal fragment of prolactin (16K PRL) inhibits tumor growth by impairing angiogenesis, but the underlying mechanisms are unknown.
Effectiveness of paliperidone palmitate vs haloperidol decanoate for maintenance treatment of schizophrenia: a randomized clinical trial.
New
Impact
Stroup et al., New York City, United States. In Jama, Jun 2014
Patients taking paliperidone palmitate had significantly higher maximum mean levels of serum prolactin (men, 34.56 µg/L [95% CI, 29.75-39.37]
Sexual dysfunction in patients with chronic renal disease: does it improve with renal transplantation?
New
Lozano et al., Bogotá, Colombia. In Transplant Proc, Dec 2013
CONCLUSION: Identified determinants associated with improvement of sexual functioning are decreased prolactin serum level, age younger than 45 years, and onset of dialysis less than 6 months.
The role of hormones on Toxoplasma gondii infection: a systematic review.
Review
New
Jiménez et al., Guadalajara, Mexico. In Front Microbiol, Dec 2013
In the human studies, the most studied hormones were testosterone, progesterone, prolactin, and 17β-estradiol.
Involvement of Mammalian RF-Amide Peptides and Their Receptors in the Modulation of Nociception in Rodents.
Review
New
Simonin et al., Illkirch-Graffenstaden, France. In Front Endocrinol (lausanne), Dec 2013
They act through five G-protein-coupled receptors and each group of peptide binds to and activates mostly one receptor: RF-amide related peptide group binds to NPFFR1, neuropeptide FF group to NPFFR2, pyroglutamylated RF-amide peptide group to QRFPR, prolactin-releasing peptide group to prolactin-releasing peptide receptor, and kisspeptin group to Kiss1R.
Does Kisspeptin Belong to the Proposed RF-Amide Peptide Family?
Review
New
Seong et al., Seoul, South Korea. In Front Endocrinol (lausanne), Dec 2013
Because of the Arg-Phe (RF) sequence at its carboxyl terminus, KISS has been proposed to be a member of the RF-amide peptide family consisting of neuropeptide FF (NPFF), neuropeptide VF (NPVF), pyroglutamylated RF-amide peptide (QRFP), and prolactin-releasing hormone (PRLH).
Mutant prolactin receptor and familial hyperprolactinemia.
New
Impact
Thakker et al., Glasgow, United Kingdom. In N Engl J Med, Dec 2013
These symptoms were not associated with pituitary tumors or multiple endocrine neoplasia but were due to a heterozygous mutation in the prolactin receptor gene, PRLR, resulting in an amino acid change from histidine to arginine at codon 188 (His188Arg).
Transformation of a transposon into a derived prolactin promoter with function during human pregnancy.
GeneRIF
Wagner et al., New Haven, United States. In Proc Natl Acad Sci U S A, 2012
analysis of transformation of a transposon into a derived prolactin promoter with function during human pregnancy
Estrogen inhibits D2S receptor-regulated Gi3 and Gs protein interactions to stimulate prolactin production and cell proliferation in lactotropic cells.
GeneRIF
Sarkar et al., New Brunswick, United States. In J Endocrinol, 2012
Results suggest that the suppression of Dopamine-2 (D2) receptor short (D2S)-regulated Gi3 inhibition of Gs protein may be one of the mechanisms controlling estradiol (E(2)-activated prolactin (PRL) synthesis and cell proliferation in lactotropes.
Serum prolactin and macroprolactin levels in diabetic nephropathy.
GeneRIF
Cetinkaya et al., Antalya, Turkey. In Clin Nephrol, 2012
Serum prolactin/macroprolactin levels increased especially in moderate to severe renal failure which was due to decreased glomerular filtration and renal parenchymal function.
Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites.
GeneRIF
Wang et al., Baltimore, United States. In Plos One, 2011
The results demonstrate that MEOX1 is a critical target gene and cofactor of PBX1 in ovarian cancers.
The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.
GeneRIF
Simon et al., Trento, Italy. In Neural Dev, 2011
In Pbx1-deficient dopaminergic neurons, the high affinity netrin-1 receptor, deleted in colon cancer, is down-regulated.
More papers using Prolactin antibodies
Functional screening of G protein-coupled receptors by measuring intracellular calcium with a fluorescence microplate reader
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Alpini Gianfranco et al., In BMC Physiology, 2001
... polyclonal (ab35349) antibody recognizing the prolactin receptor (used for the immunohistochemical and immunofluorescent evaluation of prolactin receptor in liver sections) was purchased from Abcam (Cambridge, UK) ...
Estrogen mediates the protective effects of pregnancy and chorionic gonadotropin in a mouse model of vascular injury
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Levy Andy et al., In The Journal of Endocrinology, 1998
... and 1·7 kb of 3′ PRL sequence driving Cre recombinase expression was used to generate the PRL-Cre transgenic mice ...
Internalization is required for proper Wingless signaling in Drosophila melanogaster
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Bellen Hugo J. et al., In The Journal of Cell Biology, 1995
... ), and 2 ng pRL-CMV (Promega) in 100 μL were sequentially combined with 3.2 μL Effectene Enhancer (QIAGEN), 10 μL Effectene (QIAGEN), ...
Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogene
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Kondaiah Paturu et al., In BMC Genomics, 1985
... 200 ng of pSBE-luc plasmid and 1.25 ng of pRL-CMV construct (Renilla luciferase, for transfection normalization) were transfected using Effectene reagent (Qiagen GmbH, Germany) in serum ...
Inhibition of mammary tumorigenesis in carcinogen-treated Lewis rats by suppression of prolactin secretion
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Holly J M P et al., In British Journal of Cancer, 1978
... The prolactin monoclonal antibody was bought from QED Bioscience Inc., San Diego, CA, ...
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