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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 10 Dec 2014.


Prolactin, PRL
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: HAD, CAN, AGE, Insulin, fibrillin-1
Papers using Prolactin antibodies
The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.
Korach Kenneth S. et al., In Environmental Health Perspectives, 2009
... including 0.2 μg of expression plasmid, 0.2 μg of reporter plasmid, and 0.1 μg of pRL-TK plasmid, were transfected overnight using Effectene Transfection Reagent (QIAGEN, Valencia, CA) according to ...
Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus.
Ratner Adam J., In PLoS ONE, 2007
... Plasmids pCRE-Luc and pRL-TK were obtained from Clontech and Promega, respectively ...
Cell dynamics and immune response to BLV infection: a unifying model.
Kehn-Hall Kylene, In PLoS ONE, 2006
... The plasmid expressing the Renilla luciferase via the enhancerless promoter pRL-null (pRL-renilla) was purchased from Promega Corporation (Madison WI, USA) ...
Increase in bone mineral density of patients with rheumatoid arthritis treated with anti-TNF-alpha antibody: a prospective open-label pilot study
Nanes Mark S et al., In Journal of Bone and Mineral Research, 2004
... ) The Dual Luciferase Assay System, TNF T7 Coupled Reticulocyte Lysate System, and pRL-TK control vector were purchased from Promega Corporation (Madison, WI, USA) ...
A statistical model for identifying proteins by tandem mass spectrometry
Zhu Jianhong et al., In Proteome Science, 2002
... Tris-Buffered Saline (TBS) for 4 min and then incubated at 1:300 dilution of primary anti-rabbit polyclonal prolactin antibody (Dako Cytomation, Copenhagen, Denmark) in ...
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Papers on Prolactin
Elevated serum thyroid-stimulating hormone is associated with decreased anti-Müllerian hormone in infertile women of reproductive age.
Takeda et al., Tokyo, Japan. In J Assist Reprod Genet, 09 Jan 2015
We assessed patient age, BMI and AMH, prolactin, TSH and FT4 levels of all study participations as independent variables.
Transepithelial resistance and claudin expression in trout RTgill-W1 cell line: Effects of osmoregulatory hormones.
Tipsmark et al., Fayetteville, United States. In Comp Biochem Physiol A Mol Integr Physiol, 06 Jan 2015
The effects of three osmoregulatory hormones; Gh, prolactin and cortisol on mRNA expression of three tight junction proteins were examined: claudin-10e (Cldn-10e), Cldn-30 and zonula occludens-1 (Zo-1).
Brain abscess as the initial presentation of a macroprolactinoma: Case report.
Merino-Torres et al., Valencia, Spain. In Neurocirugia (astur), 05 Jan 2015
Laboratory hormone measurements showed increased levels of prolactin and low levels of FSH, LH and testosterone.
Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression.
Schraenen et al., Leuven, Belgium. In Cell Metab, 02 Jan 2015
Locally secreted hGH binds to prolactin receptors on β cells, activates STAT5 signaling, and induces pregnancy-like changes in gene expression, thereby augmenting pancreatic β cell mass and insulin content.
Autocrine/paracrine roles of extrapituitary growth hormone and prolactin in health and disease: an overview.
Arámburo et al., Edmonton, Canada. In Gen Comp Endocrinol, 15 Dec 2014
UNLABELLED: Growth hormone (GH) and prolactin (PRL) are both endocrines that are synthesized and released from the pituitary gland into systemic circulation.
Prolactin: A versatile regulator of inflammation and autoimmune pathology.
Pedotti et al., Milano, Italy. In Autoimmun Rev, 14 Dec 2014
UNLABELLED: Prolactin (PRL) has long been proposed as an immune-stimulating and detrimental factor in autoimmune disorders.
Sex hormones in gender-specific risk for head and neck cancer: A review.
Agrawal et al., Bhopāl, India. In J Int Soc Prev Community Dent, 30 Nov 2014
So, this article is an effort to attract the attention of researchers, endocrinologists, pathologists, and clinicians toward the impending role of sex hormones, with special emphasis on progesterone, estrogen, and prolactin in HNC onset and progression, along with their therapeutic role.
Importance of macroprolactinemia in hyperprolactinemia.
Juras et al., Zagreb, Croatia. In Eur J Obstet Gynecol Reprod Biol, 20 Nov 2014
UNLABELLED: Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G.
Neuroendocrine control of photoperiodic changes in immune function.
Nelson et al., Columbus, United States. In Front Neuroendocrinol, 18 Nov 2014
We provide an overview of how photoperiod influences neuronal function and melatonin secretion, how melatonin acts directly and indirectly to govern seasonal changes in immune function, and the manner by which other neuroendocrine effectors such as glucocorticoids, prolactin, thyroid, and sex steroid hormones modulate seasonal variations in immune function.
The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus.
Luckman et al., Ann Arbor, United States. In Cell Metab, 07 Nov 2014
Leptin is a critical regulator of metabolism, which acts on brain receptors (Lepr) to reduce energy intake and increase energy expenditure.
Inclusion of endogenous hormone levels in risk prediction models of postmenopausal breast cancer.
Hankinson et al., Boston, United States. In J Clin Oncol, Nov 2014
Therefore, we evaluated whether inclusion of plasma estradiol, estrone, estrone sulfate, testosterone, dehydroepiandrosterone sulfate, prolactin, and sex hormone-binding globulin (SHBG) improved risk prediction for postmenopausal invasive breast cancer (n = 437 patient cases and n = 775 controls not using postmenopausal hormones) in the Nurses' Health Study.
Phosphatase of regenerating liver in hematopoietic stem cells and hematological malignancies.
Liu et al., Indianapolis, United States. In Cell Cycle, Oct 2014
Moreover, PRL deficiency impairs the proliferation and survival of leukemia cells through regulating oncogenic signaling pathways.
PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin.
Struman et al., Liège, Belgium. In Nat Med, Jul 2014
The N-terminal fragment of prolactin (16K PRL) inhibits tumor growth by impairing angiogenesis, but the underlying mechanisms are unknown.
Effectiveness of paliperidone palmitate vs haloperidol decanoate for maintenance treatment of schizophrenia: a randomized clinical trial.
Stroup et al., New York City, United States. In Jama, Jun 2014
Patients taking paliperidone palmitate had significantly higher maximum mean levels of serum prolactin (men, 34.56 µg/L [95% CI, 29.75-39.37]
Does vitamin D status correlate with clinical and biochemical features of polycystic ovarysyndrome in high school girls?
Ahmadi et al., Bābol, Iran. In Caspian J Intern Med, Dec 2013
No significant correlations were found between 25(OH) D levels and lipid profile, FBS, fasting insulin endocrine parameters such as testosterone, free testosterone, FSH, LH, and prolactin.
Transformation of a transposon into a derived prolactin promoter with function during human pregnancy.
Wagner et al., New Haven, United States. In Proc Natl Acad Sci U S A, 2012
analysis of transformation of a transposon into a derived prolactin promoter with function during human pregnancy
Estrogen inhibits D2S receptor-regulated Gi3 and Gs protein interactions to stimulate prolactin production and cell proliferation in lactotropic cells.
Sarkar et al., New Brunswick, United States. In J Endocrinol, 2012
Results suggest that the suppression of Dopamine-2 (D2) receptor short (D2S)-regulated Gi3 inhibition of Gs protein may be one of the mechanisms controlling estradiol (E(2)-activated prolactin (PRL) synthesis and cell proliferation in lactotropes.
Serum prolactin and macroprolactin levels in diabetic nephropathy.
Cetinkaya et al., Antalya, Turkey. In Clin Nephrol, 2012
Serum prolactin/macroprolactin levels increased especially in moderate to severe renal failure which was due to decreased glomerular filtration and renal parenchymal function.
Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites.
Wang et al., Baltimore, United States. In Plos One, 2011
The results demonstrate that MEOX1 is a critical target gene and cofactor of PBX1 in ovarian cancers.
The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.
Simon et al., Trento, Italy. In Neural Dev, 2011
In Pbx1-deficient dopaminergic neurons, the high affinity netrin-1 receptor, deleted in colon cancer, is down-regulated.
More papers using Prolactin antibodies
Functional screening of G protein-coupled receptors by measuring intracellular calcium with a fluorescence microplate reader
Alpini Gianfranco et al., In BMC Physiology, 2001
... polyclonal (ab35349) antibody recognizing the prolactin receptor (used for the immunohistochemical and immunofluorescent evaluation of prolactin receptor in liver sections) was purchased from Abcam (Cambridge, UK) ...
Estrogen mediates the protective effects of pregnancy and chorionic gonadotropin in a mouse model of vascular injury
Levy Andy et al., In The Journal of Endocrinology, 1998
... and 1·7 kb of 3′ PRL sequence driving Cre recombinase expression was used to generate the PRL-Cre transgenic mice ...
Internalization is required for proper Wingless signaling in Drosophila melanogaster
Bellen Hugo J. et al., In The Journal of Cell Biology, 1995
... ), and 2 ng pRL-CMV (Promega) in 100 μL were sequentially combined with 3.2 μL Effectene Enhancer (QIAGEN), 10 μL Effectene (QIAGEN), ...
Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogene
Kondaiah Paturu et al., In BMC Genomics, 1985
... 200 ng of pSBE-luc plasmid and 1.25 ng of pRL-CMV construct (Renilla luciferase, for transfection normalization) were transfected using Effectene reagent (Qiagen GmbH, Germany) in serum ...
Inhibition of mammary tumorigenesis in carcinogen-treated Lewis rats by suppression of prolactin secretion
Holly J M P et al., In British Journal of Cancer, 1978
... The prolactin monoclonal antibody was bought from QED Bioscience Inc., San Diego, CA, ...
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