Photochemistry of flavoprotein light sensors.
Ithaca, United States. In Nat Chem Biol, 17 Oct 2014
UNLABELLED: Three major classes of flavin photosensors, light oxygen voltage (LOV) domains, blue light sensor using FAD (BLUF) proteins and cryptochromes (CRYs), regulate diverse biological activities in response to blue light.
Disease-related mutations among Caribbean Hispanics with familial dementia.
Santiago de los Caballeros, Dominican Republic. In Mol Genet Genomic Med, 30 Sep 2014
Pathogenic mutations in the three known genes - the amyloid precursor protein (APP), presenilin 1 (PSEN1), presenilin 2 (PSEN2) - are known to cause familial Alzheimer's disease (AD) and tend to be associated with early-onset AD.
Three-dimensional structure of human γ-secretase.
Beijing, China. In Nature, 14 Sep 2014
The γ-secretase complex, comprising presenilin 1 (PS1), PEN-2, APH-1 and nicastrin, is a membrane-embedded protease that controls a number of important cellular functions through substrate cleavage.
Vibrational Spectroscopy of Photosystem I.
Atlanta, United States. In Biochim Biophys Acta, Aug 2014
To fully characterize PSI particles with different quinones incorporated into the A1 binding site nanosecond to millisecond visible absorption spectroscopy has been shown to be of considerable value, especially so when undertaken using identical samples under identical conditions to that used in time-resolved step-scan FTIR measurements.
BRCA2 variants and cardiovascular disease in a multi-ethnic study.
More papers using
Hamilton, Canada. In Bmc Med Genet, 2011
Although there was an association between two SNPs in BRCA2 and cardiovascular disease in a multi-ethnic population, these results were not replicated in two South Asian case-control studies of incident myocardial infarction.