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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 18 Mar 2014.

Pbx/knotted 1 homeobox

Prep1, PKNOX1, AtPreP1
Zinc metalloprotease pitrilysin subfamily A. Signal peptide degrading enzyme targeted to mitochondria and chloroplasts. Expressed only in siliques and flowers (from NCBI)
Top mentioned proteins: prolyl endopeptidase, ACID, Meis1, Hoxb1, PREP2
Papers on Prep1
Expression characterization and promoter activity analysis of the tilapia (Oreochromis niloticus) myosin light chain 3 promoter in skeletal muscle of fish.
New
Chen et al., Kao-hsiung, Taiwan. In Transgenic Res, 28 Feb 2014
The clone contained several putative binding sequences for transcription factors, including MEF-2, MYOG, MyoD, PKNOX1, and AREB6.
Nuclear actin polymerization from faster growing ends in the initial activation of Hox gene transcription: Are nuclear speckles involved?
New
Rivera-Pomar et al., La Plata, Argentina. In Transcription, 06 Feb 2014
The DNA-binding Pknox1-Pbx1 complex modulates Hox protein activity.
Pknox1/Prep1 regulates mitochondrial oxidative phosphorylation components in skeletal muscle.
New
Schürmann et al., Potsdam, Germany. In Mol Cell Biol, Jan 2014
The homeodomain transcription factor Prep1 was previously shown to regulate insulin sensitivity.
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
New
Blasi et al., Milano, Italy. In Dev Dyn, Jan 2014
Finally, recent advances in determining the genome-wide DNA-binding sites of PREP1, MEIS1, and PBX1, and their partial correspondence with the binding sites of some HOX proteins, are reviewed.
Phenotypical consequences of expressing the dually targeted Presequence Protease, AtPreP, exclusively in mitochondria.
New
Glaser et al., Stockholm, Sweden. In Biochimie, Jan 2014
Mitochondrial, as well as chloroplastic peptides are degraded by Presequence Protease (PreP), which is dually targeted to mitochondrial matrix and chloroplastic stroma.
Gene expression signature of non-involved lung tissue associated with survival in lung adenocarcinoma patients.
New
Dragani et al., Milano, Italy. In Carcinogenesis, Dec 2013
Ten genes for which the loge-transformed hazard ratios expressed the same direction of effect in the discovery (P < 1.0 × 10(-3)) and validation series comprised the gene expression signature associated with survival: CNTNAP1, PKNOX1, FAM156A, FRMD8, GALNTL1, TXNDC12, SNTB1, PPP3R1, SNX10 and SERPINH1.
PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice.
New
Beguinot et al., Napoli, Italy. In Diabetologia, Dec 2013
AIMS/HYPOTHESIS: The aim of this study was to investigate the function of Prep1 (also known as Pknox1) in hepatic lipogenesis.
A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation.
Zhou et al., College Station, United States. In Circulation, 2012
In addition, we identified Pknox1 as a genuine miR-223 target gene and an essential regulator for macrophage polarization.
A novel mitochondrial and chloroplast peptidasome, PreP.
Review
Glaser et al., Stockholm, Sweden. In Physiol Plant, 2012
A novel mitochondrial and chloroplast peptidasome, the Presequence Protease (PreP) degrades organellar targeting peptides as well as other unstructured peptides up to 65 amino acid residues in length.
Non-synonymous variants in pre-B cell leukemia homeobox (PBX) genes are associated with congenital heart defects.
Bowles et al., Salt Lake City, United States. In Eur J Med Genet, 2012
The coding exons of PBX1-4, PKNOX1, PKNOX2, MEIS1-3, and PBXIP1 were amplified by polymerase chain reaction and the products analyzed on a lightscanner.
Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia.
GeneRIF
van 't Wout et al., Amsterdam, Netherlands. In Plos One, 2011
Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia
C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein.
GeneRIF
Sauvageau et al., Montréal, Canada. In Blood, 2011
The C-terminal domain of MEIS1 confers to PKNOX1 an ectopic transactivating function that promotes leukemogenesis by regulating expression of genes involved in chromatin accessibility and cell cycle progression.
A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.
GeneRIF
Selleri et al., New York City, United States. In Dev Cell, 2011
Loss of Pbx-Wnt-p63-Irf6 regulatory module results in clefting.
Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability.
GeneRIF
Blasi et al., Milano, Italy. In Proc Natl Acad Sci U S A, 2011
The tumor suppressor role of Prep1 is associated with the maintenance of genomic stability.
Regulation of CCL2 expression by an upstream TALE homeodomain protein-binding site that synergizes with the site created by the A-2578G SNP.
Clements et al., Baltimore, United States. In Plos One, 2010
We previously demonstrated that the -2578 G polymorphism creates a TALE homeodomain protein binding site (TALE binding site) for PREP1/PBX2 transcription factors.
MEIS1, PREP1, and PBX4 are differentially expressed in acute lymphoblastic leukemia: association of MEIS1 expression with higher proliferation and chemotherapy resistance.
GeneRIF
Jave-Suárez et al., Guadalajara, Mexico. In J Exp Clin Cancer Res, 2010
High levels of MEIS1 and PREP1, and low levels of PBX4 expression were founded in samples of patients with ALL.
Two novel mitochondrial and chloroplastic targeting-peptide-degrading peptidasomes in A. thaliana, AtPreP1 and AtPreP2.
Review
GeneRIF
Bhushan et al., Stockholm, Sweden. In Biol Chem, 2006
AtPreP1 and AtPreP2 genes are differentially expressed in Arabidopsis
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