Epithelial-mesenchymal transition-related factors in solid tumor and hematological malignancy.
Taipei, Taiwan. In J Chin Med Assoc, Aug 2015
Several EMT regulators including Snail, Zeb1, Zeb2, and Twist in solid tumor and Sox4, distal-less homeobox gene 4 (DLX4), Prdm14, Bmi1, and the forkhead box family in hematological malignancy are reviewed with regard to their signaling pathways, regulatory mechanisms, and clinical interactions.
Induction of mouse germ-cell fate by transcription factors in vitro.
Kyoto, Japan. In Nature, 2013
Here we show that, without cytokines, simultaneous overexpression of three transcription factors, Blimp1 (also known as Prdm1), Prdm14 and Tfap2c (also known as AP2γ), directs EpiLCs, but not embryonic stem cells, swiftly and efficiently into a PGC state.