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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

PR domain containing 12

PRDM12
Top mentioned proteins: Histone, Blimp-1, RIZ1, FATE, Qin
Papers on PRDM12
Regulation of nucleus accumbens transcript levels in mice by early-life social stress and cocaine.
New
Carola et al., Roma, Italy. In Neuropharmacology, Jan 2016
We characterized 4 candidates with regard to their significant neurobiological relevance (ZIC1, ZIC2, FABP7, and PRDM12) and measured their expression in the NAC by immunohistochemistry.
New Mendelian Disorders of Painlessness.
Review
New
Woods et al., Cambridge, United Kingdom. In Trends Neurosci, Nov 2015
The discovery of new genes essential for sensing pain (SCN11A, PRDM12, and CLTCL1) has provided unexpected insights into the biological mechanisms that drive distinct stages of nociception.
Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus.
New
Van Campenhout et al., Brussels, Belgium. In Development, Nov 2015
Here, we show that the transcription factor Prdm12 is selectively expressed in p1 progenitors of the hindbrain and spinal cord in the frog embryo, and that a similar restricted expression profile is observed in the nerve cord of other vertebrates as well as of the cephalochordate amphioxus.
Molecular characterization and follow-up of five CML patients with new BCR-ABL1 fusion transcripts.
New
GBMHM (Groupe des Biologistes Moléculaires des Hémopathies Malignes et al., Saint-Pierre-des-Corps, France. In Genes Chromosomes Cancer, Oct 2015
The other two cases revealed a complex e8-[ins]-a2 fusion transcript involving a third partner gene, PRDM12 and SPECC1L, respectively.
Transcriptional regulator PRDM12 is essential for human pain perception.
New
Impact
Senderek et al., Cambridge, United Kingdom. In Nat Genet, Jul 2015
Here we identified 10 different homozygous mutations in PRDM12 (encoding PRDI-BF1 and RIZ homology domain-containing protein 12) in subjects with CIP from 11 families.
The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus.
New
Michiue et al., Tokyo, Japan. In Dev Biol, Apr 2015
During the early neurula stage, PRDM12 was expressed in the lateral pre-placodal ectoderm and repressed the expression of neural crest specifier genes via methylation of histone H3K9.
The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception.
Penninger et al., Vienna, Austria. In Cell Cycle, 2014
PR homology domain-containing member 12 (PRDM12) belongs to a family of conserved transcription factors implicated in cell fate decisions.
Prdm12 is induced by retinoic acid and exhibits anti-proliferative properties through the cell cycle modulation of P19 embryonic carcinoma cells.
Shinkai et al., Kyoto, Japan. In Cell Struct Funct, 2012
Here, we report that Prdm12 recruits G9a to methylate histone H3 on lysine 9 through its zinc finger domains.
Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.
Moore et al., Wako, Japan. In Plos One, 2007
In developing telencephalon Prdm12 and 16 are expressed in the ventricular zone in a lateral to medial graded manner, and Prdm8 is expressed in a complementary domain in postmitotic neurons.
A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
GeneRIF
Nacheva et al., In Leukemia, 2004
Down-regulation of PRDM12 is associated with the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion
Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome.
Squire et al., Toronto, Canada. In Leukemia, 2003
Of the four ESTs and/or genes that map to the 120 kb region, the putative tumor suppressor PRDM12 is the strongest candidate gene.
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