gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Protein phosphatase 1, catalytic subunit, gamma isozyme

PPP1CC, PP-1G, PPIG
one of several catalytic subunit isoforms of protein phosphatase 1 [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: Insulin, PP2A, PP1, ACID, CAN
Papers on PPP1CC
Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction.
New
Yu et al., Xiamen, China. In J Cell Sci, Oct 2015
Thus, we propose that Cep85 is a bona fide Nek2A-binding partner that surrounds the proximal ends of centrioles where it cooperates with PP1γ (also known as PPP1CC) to antagonize Nek2A activity in order to maintain the centrosome integrity in interphase in mammalian cells.
Gene expression profile analysis of colorectal cancer to investigate potential mechanisms using bioinformatics.
Hu et al., Jinan, China. In Onco Targets Ther, 2014
Moreover, FOS, FN1, PPP1CC, and CYP2B6 were selected as hub genes in the PPI networks.
Detecting key genes regulated by miRNAs in dysfunctional crosstalk pathway of myasthenia gravis.
Wang et al., Harbin, China. In Biomed Res Int, 2014
Furthermore, 14 key genes regulated by miRNAs were detected, of which six-MAPK1, RAF1, PGF, PDGFRA, EP300, and PPP1CC-mediated interactions between the dysregulated pathways.
Genome-wide analysis reveals population structure and selection in Chinese indigenous sheep breeds.
Du et al., Beijing, China. In Bmc Genomics, 2014
We detected three strong selection windows involving three functional genes: RXFP2, PPP1CC and PDGFD.
Phosphoprotein phosphatase 1 complexes in spermatogenesis.
Review
Fardilha et al., Aveiro, Portugal. In Curr Mol Pharmacol, 2013
Three genes, PPP1CA, PPP1CB and PPP1CC, encode four PPP1C isoforms, PPP1CA, PPP1CB, PPP1CC1, and PPP1CC2.
TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network.
da Cruz E Silva et al., Aveiro, Portugal. In Biol Open, 2013
The overlay assays confirm that TCTEX1D4 interacts with the different spliced isoforms of PPP1CC.
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.
von Brunn et al., Hamburg, Germany. In Plos Pathog, 2011
In this study, we used a systems biology approach employing a genome-wide yeast-two hybrid interaction screen to identify immunopilins (PPIA, PPIB, PPIH, PPIG, FKBP1A, FKBP1B) as interaction partners of the CoV non-structural protein 1 (Nsp1).
Identification and prioritization of NUAK1 and PPP1CC as positional candidate loci for skeletal muscle strength phenotypes.
GeneRIF
Thomis et al., Leuven, Belgium. In Physiol Genomics, 2011
NUAK1 and PPP1CC are identified as positional candidate loci for skeletal muscle strength phenotypes.
Plk1 controls the Nek2A-PP1γ antagonism in centrosome disjunction.
GeneRIF
Schiebel et al., Heidelberg, Germany. In Curr Biol, 2011
The counteracting Nek2A and PP1gamma activities on the centrosome linker are controlled by Plk1.
Protein phosphatase 1γ is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage.
GeneRIF
Nakanishi et al., Nagoya, Japan. In Embo Rep, 2010
The ataxia telangiectasia, mutated and Rad3-related-Chk1 axis regulates H3-pThr 11 dephosphorylation on DNA damage, at least in part by the activation of PP1gamma through Chk1-dependent inhibition of cyclin dependent kinases.
Identification and characterization of a novel human PP1 phosphatase complex.
GeneRIF
Skalnik et al., Indianapolis, United States. In J Biol Chem, 2010
mammalian Wdr82 functions in a variety of cellular processes; PTW/PP1 phosphatase complex (PNUTS, Tox4, Wdr82, PP1) has a role in the regulation of chromatin structure during the transition from mitosis into interphase
Loss of protein phosphatase 1c{gamma} (PPP1CC) leads to impaired spermatogenesis associated with defects in chromatin condensation and acrosome development: an ultrastructural analysis.
Varmuza et al., Toronto, Canada. In Reproduction, 2010
Mouse models of male infertility such as the Ppp1cc knockout mouse display very similar phenotypes to humans with testicular failure.
Regulation of hyperactivation by PPP2 in hamster spermatozoa.
Suzuki et al., Tochigi, Japan. In Reproduction, 2010
Protein phosphatases PPP1CA, PPP1CC, PPP2, and PPP3 are present in hamster sperm.
Assessment of gravitational stress on heart rate variability during maneuvers on high performance jet flights.
Guadagno et al., Milano, Italy. In Conf Proc Ieee Eng Med Biol Soc, 2009
The flight protocol included a maneuver eliciting a reference +5Gz acceleration for 15 seconds (Ref+5G), followed, after a while, by a push-pull maneuver with a profile characterized by a 5-s acceleration at -1Gz (PP-1G) and, with a 1G/s onset, by 15 seconds at +5Gz (PP+5G), so to induce the push-pull gravitational stress.
Serotonin(1A)-receptor-dependent signaling proteins in mouse hippocampus.
Lubec et al., Vienna, Austria. In Neuropharmacology, 2009
Nucleoside diphosphate kinase A (NDK A, synonym: nm23), Dual specificity mitogen-activated protein kinase kinase 1 (MAPKK1, synonym: MEK), Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G), Septin-5, were reduced in the KO mice.
Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.
GeneRIF
Küntziger et al., Oslo, Norway. In Hum Mol Genet, 2009
Protein phosphatase 1 binding occurs through a conserved RVXF motif found in the KH domain of AKAP149.
Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin.
Review
Pandey et al., Montréal, Canada. In Mol Cell Biochem, 1998
Most importantly, recent studies have focussed on the possible role of glycogen synthase kinase-3 (GSK-3) and glycogen bound protein phosphatase-1 (PP-1G) in the activation of glycogen synthase (GS) - a key enzyme of glycogen metabolism.
Protein phosphatase-1 and insulin action.
Review
Begum et al., Mineola, United States. In Mol Cell Biochem, 1998
Our in vivo studies using L6 rat skeletal muscle cells and freshly isolated adipocytes indicate that insulin stimulates PP-1 by increasing the phosphorylation status of its regulatory subunit (PP-1G).
The structure and regulation of protein phosphatases.
Review
Impact
Cohen, Dundee, United Kingdom. In Annu Rev Biochem, 1988
This concept is best established for the glycogen-bound enzymes in skeletal muscle and liver (PP-1G) and the myofibrillar form (PP-1M) in skeletal muscle.
share on facebooktweetadd +1mail to friends