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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Periplakin

PPL
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, ACID, HAD, fibrillin-1, V1a
Papers using PPL antibodies
WebACT - an online companion for the Artemis Comparison Tool.
Supplier
Carlow Clotilde K. S., In PLoS ONE, 2004
... The Home Office license number is PPL 60/03899 and experimental IDs for these studies were ...
Deficient geranylgeranylation of Ram/Rab27 in choroideremia
Supplier
Seabra Miguel C et al., In Traffic (Copenhagen, Denmark), 1994
... colonies were bred and maintained on 12-h light/dark cycle under UK project license PPL 70/6210 at the Central Biomedical Services of Imperial College ...
Papers on PPL
Circulating microparticles and the risk of thrombosis in inherited deficiencies of antithrombin, protein C and protein S.
New
Simioni et al., Padova, Italy. In Thromb Haemost, Jan 2016
Plasma levels of annexin V-MP, endothelial-derived MP (EMP), platelet-derived MP (PMP), tissue factor-bearing MP (TF+) and the MP procoagulant activity (PPL) were measured in 132 carriers of natural anticoagulant deficiencies (25 antithrombin, 63 protein C and 64 protein S defect) and in 132 age and gender-matched healthy controls.
A method to confer Protein L binding ability to any antibody fragment.
New
Aubrey et al., Tours, France. In Mabs, Jan 2016
The most effective, specific and fastest method of purification is an affinity chromatography on protein L (PpL) matrix.
Piperlongumine for Enhancing Oral Bioavailability and Cytotoxicity of Docetaxel in Triple-Negative Breast Cancer.
New
Singh et al., Hyderābād, India. In J Pharm Sci, Dec 2015
The research was aimed to investigate the effect of piperlongumine (PPL) on human liver microsomal metabolism, Caco-2 permeability, and cytotoxicity of DTX in triple-negative breast cancer cell lines.
The effect of energy balance on the transcriptome of bovine granulosa cells at 60 days postpartum.
New
Sirard et al., Québec, Canada. In Theriogenology, Nov 2015
Genes linked with cellular organization (KRT4 and PPL), proliferation (TACSTD2), and fatty acids metabolism (VNN2) were downregulated in granulosa cells from animals with severe NEB.
Synchronous primary pulmonary lymphoma presenting with pulmonary adenocarcinoma: A case report and literature review.
New
Gao et al., Beijing, China. In Indian J Cancer, Nov 2015
Primary pulmonary lymphoma (PPL) is very rare in clinics accounting for only 0.5-1% of primary lung tumors.
Evaluation of Suitable Reference Genes for Normalization of qPCR Gene Expression Studies in Brinjal (Solanum melongena L.) During Fruit Developmental Stages.
New
Kumar et al., New Delhi, India. In Appl Biochem Biotechnol, Nov 2015
and studied their expression profiles by qPCR during six different fruit developmental stages (0, 5, 10, 20, 30, and 50 days post anthesis) along with leaf samples of the Pusa Purple Long (PPL) variety.
Update in primary pulmonary lymphomas.
Review
New
Fein et al., Hempstead, United States. In Curr Opin Pulm Med, Jul 2015
PURPOSE OF REVIEW: Despite the fact that primary pulmonary lymphoma (PPL) is a rare lung tumour, significant advances addressing clinical features, histological diagnosis, prognostic criteria and therapeutic management of this disease have been made within the past decade.
Anchored multiplex PCR for targeted next-generation sequencing.
Impact
Le et al., Boston, United States. In Nat Med, 2014
On the basis of our experience with performing AMP on 986 clinical FFPE samples, we show its potential as both a robust clinical assay and a powerful discovery tool, which we used to identify new therapeutically important gene fusions: ARHGEF2-NTRK1 and CHTOP-NTRK1 in glioblastoma, MSN-ROS1, TRIM4-BRAF, VAMP2-NRG1, TPM3-NTRK1 and RUFY2-RET in lung cancer, FGFR2-CREB5 in cholangiocarcinoma and PPL-NTRK1 in thyroid carcinoma.
Bone engineering by phosphorylated-pullulan and β-TCP composite.
Matsukawa et al., Okayama, Japan. In Biomed Mater, 2014
Recently, we created phosphorylated-pullulan (PPL), capable of binding to hydroxyapatite in bones and teeth.
Effect of regulating airway pressure on intrathoracic pressure and vital organ perfusion pressure during cardiopulmonary resuscitation: a non-randomized interventional cross-over study.
Lurie et al., Minneapolis, United States. In Scand J Trauma Resusc Emerg Med, 2014
BACKGROUND: The objective of this investigation was to evaluate changes in intrathoracic pressure (Ppl), airway pressure (Paw) and vital organ perfusion pressures during standard and intrathoracic pressure regulation (IPR)-assisted cardiopulmonary resuscitation (CPR).
Gastric mucosa-associated lymphoid tissue lymphoma associated with pancreatic non-Hodgkin's lymphoma: A case report.
El-Gemeie et al., Cairo, Egypt. In Endosc Ultrasound, 2014
Primary pancreatic lymphoma (PPL) is an extremely rare tumor (1% incidence) and is often confused with pancreatic adenocarcinoma.
Adhesion molecule periplakin is involved in cellular movement and attachment in pharyngeal squamous cancer cells.
GeneRIF
Nomura et al., Chiba, Japan. In Bmc Cell Biol, 2010
involved in cellular movement and attachment in pharyngeal squamous cancer cells
Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress.
GeneRIF
Young et al., Nashville, United States. In Cardiovasc Pathol, 2010
Sciellin, SPRR3, and periplakin transcripts were all upregulated (4.67-, 4.95-, 2.77-fold, respectively) by prolonged exposure to cyclic strain (24-72 h), but not at earlier time points.
A diagnostic algorithm for metabolic myopathies.
Review
Hirano et al., New York City, United States. In Curr Neurol Neurosci Rep, 2010
CK-creatine kinase; COX-cytochrome c oxidase; CPT-carnitine palmitoyl transferase; cyt b-cytochrome b; mtDNA-mitochondrial DNA; nDNA-nuclear DNA; PFK-phosphofructokinase; PGAM-phosphoglycerate mutase; PGK-phosphoglycerate kinase; PPL-myophosphorylase; RRF-ragged red fibers; TFP-trifunctional protein deficiency; VLCAD-very long-chain acyl-coenzyme A dehydrogenase.
Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus.
GeneRIF
Zhu et al., Beijing, China. In Arch Dermatol Res, 2009
autoantibodies are detected in patients with paraneoplastic pemphigus
Effect of acute inflation on the mechanics of the inspiratory muscles.
Review
Wilson et al., Brussels, Belgium. In J Appl Physiol, 2009
When the lung is inflated acutely, the capacity of the diaphragm to generate pressure, in particular pleural pressure (Ppl), is impaired because the muscle during contraction is shorter and generates less force.
Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier.
GeneRIF
Watt et al., Cambridge, United Kingdom. In J Cell Biol, 2008
Thus, combined loss of the cornified envelope proteins not only impairs the epidermal barrier, but also changes the composition of T cell subpopulations in the skin.
Cytolinker cross-talk: periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration.
GeneRIF
Määttä et al., Durham, United Kingdom. In Exp Cell Res, 2007
A novel functional co-localisation is identified between two plakin cytolinker proteins.
Content-dependent activity of lung surfactant protein B in mixtures with lipids.
Review
Notter et al., Rochester, United States. In Am J Physiol Lung Cell Mol Physiol, 2002
The content-dependent activity of surfactant protein (SP)-B was studied in mixtures with dipalmitoyl phosphatidylcholine (DPPC), synthetic lipids (SL), and purified phospholipids (PPL) from calf lung surfactant extract (CLSE).
Technology evaluation: transgenic alpha-1-antitrypsin (AAT), PPL therapeutics.
Review
Tebbutt, Dunedin, New Zealand. In Curr Opin Mol Ther, 2000
PPL Therapeutics is developing transgenic alpha-1-antitrypsin for the treatment of cystic fibrosis lung disease and other conditions in which connective tissue is broken down irreversibly.
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