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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Protein phosphatase 4, regulatory subunit 2

PP4R2, PPP4R2, Psy4, Psy4p
Top mentioned proteins: PPX, fibrillin-1, H2A, PP2A, TIP41
Papers on PP4R2
Dephosphorylation of DBC1 by Protein Phosphatase 4 Is Important for p53-Mediated Cellular Functions.
Lee et al., Kwangju, South Korea. In Mol Cells, Aug 2015
PP4R2, a regulatory subunit of PP4, mediates the interaction between DBC1 and PP4C, a catalytic subunit.
The Phytoene synthase gene family of apple (Malus x domestica) and its role in controlling fruit carotenoid content.
Allan et al., Auckland, New Zealand. In Bmc Plant Biol, 2014
RESULTS: The apple PSY gene family, containing six members, was predicted to have three functional members, PSY1, PSY2, and PSY4, based on translation of the predicted gene sequences and/or corresponding cDNAs.
TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.
Kong et al., Duarte, United States. In Plos One, 2014
Knockdown of TIPRL resulted in increased PP4 phosphatase activity and formation of the active PP4-C/PP4R2 complex known to dephosphorylate ╬│-H2AX.
[HSM6 gene is identical to PSY4 gene in Saccharomyces cerevisiae yeasts].
Korolev et al., In Genetika, 2013
HSM6 gene was mapped on the left arm of chromosome 11 in the region where the PSY4 gene is located.
PPP4R2 regulates neuronal cell differentiation and survival, functionally cooperating with SMN.
Di Cunto et al., Torino, Italy. In Eur J Cell Biol, 2012
PPP4R2 affects the survival of neuronal cells in response to DNA damage.
Protein phosphatase PP4 is involved in NHEJ-mediated repair of DNA double-strand breaks.
Xu et al., Beijing, China. In Cell Cycle, 2012
Both PP4C and its regulatory subunit PP4R2 physically interacted with the chromatin condensation factor KAP1 (KRAB-associated protein 1).
PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression.
Cairns et al., Salt Lake City, United States. In Embo J, 2012
Here, we establish the protein phosphatase 4 (PP4) complex as the main Maf1 phosphatase, and define the involved catalytic (Pph3), scaffold (Psy2) and regulatory subunits (Rrd1, Tip41), as well as uninvolved subunits (Psy4, Rrd2).
A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination.
Chowdhury et al., Boston, United States. In Nat Struct Mol Biol, 2010
PP4R2, a regulatory subunit of PP4, mediates the DNA damage-dependent association between RPA2 and the PP4C catalytic subunit.
Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs.
Yanagawa et al., Tsuruoka, Japan. In Proc Natl Acad Sci U S A, 2009
The search for NLSs that overlap the consensus CDK1 phosphorylation site by using cNLS Mapper identified all previously reported and 5 previously uncharacterized yeast proteins (Yen1, Psy4, Pds1, Msa1, and Dna2) displaying CDK1- and cell cycle-regulated nuclear transport.
Protein phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions.
Somers et al., Singapore, Singapore. In Genes Dev, 2009
Attenuating the function of either the catalytic subunit of PP4 (PP4C; Pp4-19C in Drosophila) or of another regulatory subunit, PP4R2 (PPP4R2r in Drosophila), leads to similar defects in the localization of Mira and associated proteins.
PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.
Gingras et al., Toronto, Canada. In J Biol Chem, 2008
PP4c.PP4R4 complexes exhibit phosphatase activity toward a fluorogenic substrate and gammaH2AX, but this activity is lower than that associated with the PP4c.PP4R2.PP4R3 complex, which itself is less active than the free PP4c catalytic subunit.
Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage.
Cohen et al., Dundee, United Kingdom. In Febs J, 2008
Results suggest that the trimeric Pph3p-Psy4p-Psy2p complex may dephosphorylate both gammaH2AX and Rad53p.
A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.
Lieberman et al., Boston, United States. In Mol Cell, 2008
A three-protein PP4 phosphatase complex in mammalian cells, containing PP4C, PP4R2, and PP4R3beta, specifically dephosphorylates ATR-mediated gamma-H2AX generated during DNA replication.
MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis.
Firtel et al., San Diego, United States. In Mol Cell Biol, 2007
In other organisms, the protein phosphatase 4 catalytic subunit, PP4C, functions in a complex with the regulatory subunits PP4R2 and PP4R3 to control recovery from DNA damage.
Familial pericentric inversion chromosome 3 and R448C mutation of CYP11B1 gene in Turkish kindred with 11beta-hydroxylase deficiency.
Sakizli et al., ─░zmir, Turkey. In J Endocrinol Invest, 2007
The breakpoint at 3p included one interesting gene PPP4R2.
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