Spatial Regulation of Greatwall by Cdk1 and PP2A-Tws in the Cell Cycle.
Montréal, Canada. In Cell Cycle, Feb 2016
UNASSIGNED: Entry into mitosis requires the phosphorylation of multiple substrates by cyclin B-Cdk1, while exit from mitosis requires their dephosphorylation, which depends largely on the phosphatase PP2A in complex with its B55 regulatory subunit (Tws in Drosophila).
Durham, United States. In Cold Spring Harb Perspect Biol, Oct 2015
Protein kinase and phosphatase signaling pathways involving Mos, CDK1, RSK, and PP2A regulate meiosis during maturation of the oocyte.
A PP1-PP2A phosphatase relay controls mitotic progression.
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Manchester, United Kingdom. In Nature, 2015
Although Cdc14 phosphatase drives this reversal in budding yeast, protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) activities have each been independently linked to mitotic exit control in other eukaryotes.
Apaf-1 is a transcriptional target for E2F and p53
In Molecular Cancer, 2000
... pCdk5, Cdk5, p35, Bcl-2, cytochrome-C, PARP, COX-IV, β-Tubulin, β-Actin, HRP-linked secondary antibodies, Control, p53 and PP2A siRNAs were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ... Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
In The Journal of Cell Biology, 1997
... Signaling Technology), PP1-β (rabbit A300-905A; Bethyl Laboratories, Inc.), PP1-γ (goat SC-6108; Santa Cruz Biotechnology, Inc.), PP2A (mouse 610555; BD), TPX2 (mouse ab32795; Abcam), Hec1 (mouse GTX70268; GeneTex, ...