FRET and mechanobiology.more suppliers
In PLoS ONE, 2008
... A Src-selective tyrosine kinase inhibitor, 4-Amino-5-(4-methylphenyl)-7-(t-butyl) parasol (3,4-d)-pyrimidine (PP1) from Biomol was used at final ...
Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells.
Dschang, Cameroon. In Am J Physiol Lung Cell Mol Physiol, Feb 2016
Pretreatment with the inhibitor of c-Src (PP1), ROS (Edaravone), NADPH oxidase (apocynin and diphenyleneiodonium chloride), EGFR (AG1478), PDGFR (AG1296), PI3K (LY294002), MEK1/2 (U0126), or NF-κB (Bay11-7082) and transfection with siRNAs of c-Src, EGFR, PDGFR, Akt, p47(phox), Nox2, Nox4, p42, and p65 markedly reduced LPS-induced ICAM-1 expression and monocyte adherence to HPAEpiCs challenged with LPS.
A PP1-PP2A phosphatase relay controls mitotic progression.
Manchester, United Kingdom. In Nature, 2015
Although Cdc14 phosphatase drives this reversal in budding yeast, protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) activities have each been independently linked to mitotic exit control in other eukaryotes.
Feedback control of chromosome separation by a midzone Aurora B gradient.
More papers using
Porto, Portugal. In Science, 2014
A midzone-associated Aurora B gradient was found to monitor chromosome position along the division axis and to prevent premature chromosome decondensation by retaining Condensin I. PP1/PP2A phosphatases counteracted this gradient and promoted chromosome decondensation and NER.