FRET and mechanobiology.more suppliers
In PLoS ONE, 2008
... A Src-selective tyrosine kinase inhibitor, 4-Amino-5-(4-methylphenyl)-7-(t-butyl) parasol (3,4-d)-pyrimidine (PP1) from Biomol was used at final ...
Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells.
Dschang, Cameroon. In Am J Physiol Lung Cell Mol Physiol, Feb 2016
Pretreatment with the inhibitor of c-Src (PP1), ROS (Edaravone), NADPH oxidase (apocynin and diphenyleneiodonium chloride), EGFR (AG1478), PDGFR (AG1296), PI3K (LY294002), MEK1/2 (U0126), or NF-κB (Bay11-7082) and transfection with siRNAs of c-Src, EGFR, PDGFR, Akt, p47(phox), Nox2, Nox4, p42, and p65 markedly reduced LPS-induced ICAM-1 expression and monocyte adherence to HPAEpiCs challenged with LPS.
A PP1-PP2A phosphatase relay controls mitotic progression.
Manchester, United Kingdom. In Nature, 2015
Although Cdc14 phosphatase drives this reversal in budding yeast, protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) activities have each been independently linked to mitotic exit control in other eukaryotes.
Phytotoxicity associated to microcystins: a review.
Piracicaba, Brazil. In Braz J Biol, 2014
Microcystins (MC) are the most studied toxins of cyanobacteria since they are widely distributed and account for several cases of human and animal poisoning, being potent inhibitors of the serine/threonine protein phosphatases 1 (PP1) and 2A (PP2A).
Feedback control of chromosome separation by a midzone Aurora B gradient.
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Porto, Portugal. In Science, 2014
A midzone-associated Aurora B gradient was found to monitor chromosome position along the division axis and to prevent premature chromosome decondensation by retaining Condensin I. PP1/PP2A phosphatases counteracted this gradient and promoted chromosome decondensation and NER.