gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Poliovirus receptor

poliovirus receptor, CD155, nectin-2
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] (from NCBI)
Papers on poliovirus receptor
The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR.
GeneRIF
Doria et al., Roma, Italy. In J Virol, 2012
the PVR downmodulation by Nef and Vpu is a strategy evolved by HIV-1 to prevent NK cell-mediated lysis of infected cells.
Necl-5/poliovirus receptor interacts with VEGFR2 and regulates VEGF-induced angiogenesis.
GeneRIF
Rikitake et al., Kōbe, Japan. In Circ Res, 2012
Necl-5/poliovirus receptor interacts with VEGFR2 and regulates VEGF-induced angiogenesis.
The toll-like receptor 3-mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice.
GeneRIF
Koike et al., Tokyo, Japan. In J Virol, 2012
The TLR3-TRIF mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice.
Receptors for hyaluronic acid and poliovirus: a combinatorial role in glioma invasion?
GeneRIF
Pilkington et al., Portsmouth, United Kingdom. In Plos One, 2011
This investigation has enhanced understanding of cell invasion and confirmed CD44 to play a more significant role in this biological process than CD155.
The TLR3/TICAM-1 pathway is mandatory for innate immune responses to poliovirus infection.
GeneRIF
Seya et al., Sapporo, Japan. In J Immunol, 2011
The host TICAM-1 pathway, particularly in macrophages, serves as a source of type I interferon induction that protects poliovirus (PV) receptor-bearing transgenic mice from PV infection and paralytic death.
share on facebooktweetadd +1mail to friends