Identification of CD112R as a novel checkpoint for human T cells.
Hangzhou, China. In J Exp Med, Feb 2016
UNASSIGNED: T cell immunoglobulin and ITIM domain (TIGIT) and CD226 emerge as a novel T cell cosignaling pathway in which CD226 and TIGIT serve as costimulatory and coinhibitory receptors, respectively, for the ligands CD155 and CD112.
Monocyte trafficking across the vessel wall.
Los Angeles, United States. In Cardiovasc Res, Sep 2015
The emerging roles of endothelial junctional molecules like vascular endothelial-cadherin and the junctional adhesion molecule family, adhesion molecules such as intercellular adhesion molecule-1, molecules localized to the lateral border recycling compartment like cluster of differentiation 99, platelet/endothelial cell adhesion molecule-1, and poliovirus receptor (CD155), as well as other cell surface molecules such as cluster of differentiation 146 and ephrins in transendothelial migration are discussed.
Pathological consequences of systemic measles virus infection.
Boston, United States. In J Pathol, 2015
The identification of poliovirus receptor-like 4 (PVRL4) as the second natural receptor for measles virus (MV) has closed a major gap in our understanding of measles pathogenesis, and explains how this predominantly lymphotropic virus breaks through epithelial barriers to transmit to a susceptible host.
Molecular aspects of poliovirus pathogenesis.
Tokyo, Japan. In Proc Jpn Acad Ser B Phys Biol Sci, 2007
The development of a transgenic mouse model carrying the human poliovirus receptor has made it possible to investigate the molecular mechanisms of the viral dissemination process in a whole organism.