Visualizing the Path of DNA through Proteins Using DREEM Imaging.
Chapel Hill, United States. In Mol Cell, Feb 2016
Imaging of nucleosomes and DNA mismatch repair complexes demonstrates that DREEM can reveal both the path of the DNA wrapping around histones and the path of DNA as it passes through both single proteins and multiprotein complexes.
Review: Clinical aspects of hereditary DNA Mismatch repair gene mutations.
Groningen, Netherlands. In Dna Repair (amst), Jan 2016
UNASSIGNED: Inherited mutations of the DNA Mismatch repair genes MLH1, MSH2, MSH6 and PMS2 can result in two hereditary tumor syndromes: the adult-onset autosomal dominant Lynch syndrome, previously referred to as Hereditary Non-Polyposis Colorectal Cancer (HNPCC) and the childhood-onset autosomal recessive Constitutional Mismatch Repair Deficiency syndrome.
Protein-protein interactions in DNA mismatch repair.
Gießen, Germany. In Dna Repair (amst), Jan 2016
UNASSIGNED: The principal DNA mismatch repair proteins MutS and MutL are versatile enzymes that couple DNA mismatch or damage recognition to other cellular processes.
DNA triplet repeat expansion and mismatch repair.
West Chester, United States. In Annu Rev Biochem, 2014
DNA mismatch repair is a conserved antimutagenic pathway that maintains genomic stability through rectification of DNA replication errors and attenuation of chromosomal rearrangements.