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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 06 Dec 2014.

Mannose phosphate isomerase

PMI, Mannose-6-Phosphate Isomerase, mannose phosphate isomerase, PM-1
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, HAD, CAN, AGE, OUT
Papers on PMI
Hemp (Cannabis sativa L.).
Punja et al., Coventry, United Kingdom. In Methods Mol Biol, 31 Dec 2014
The plasmid contains a phosphomannose isomerase (PMI) selectable marker gene.
Rosuvastatin May Reduce the Incidence of Cardiovascular Events in Patients with Acute Coronary Syndromes Receiving Percutaneous Coronary Intervention by Suppressing miR-155/SHIP-1 Signaling Pathway.
Mo et al., Yulin, China. In Cardiovasc Ther, 31 Dec 2014
RESULTS: Compared with placebo, rosuvastatin treatment significantly reduced the incidence of periprocedural myocardial infarction (PMI) and levels of cardiac troponin I (cTnI) associated with decreased relative expression of serum miR-155, levels of inflammatory cytokines (INF-γ, TNF-α, and IL-6), increased SHIP-1 expression and CD4(+) FoxP3(+) Treg percentage values (P < 0.05).
The dual CCR5 and CCR2 inhibitor cenicriviroc does not redistribute HIV into extracellular space: implications for plasma viral load and intracellular DNA decline.
Wainberg et al., Montréal, Canada. In J Antimicrob Chemother, 27 Dec 2014
METHODS: We infected PM-1 cells with CCR5-tropic HIV-1 BaL in the presence or absence of inhibitory concentrations of cenicriviroc (20 nM) or maraviroc (50 nM) or controls.
PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy.
Campanella et al., London, United Kingdom. In Chem Biol, 13 Dec 2014
The compound, P62-mediated mitophagy inducer (PMI), activates mitophagy without recruiting Parkin or collapsing ΔΨm and retains activity in cells devoid of a fully functional PINK1/Parkin pathway.
The effect of scapular posterior tilt exercise, pectoralis minor stretching, and shoulder brace on scapular alignment and muscles activity in subjects with round-shoulder posture.
Choi et al., Wŏnju, South Korea. In J Electromyogr Kinesiol, 28 Nov 2014
Objectives: The purpose of this study was to compare the SPT, PM stretch+SPT, and SPT+brace on RSP, PM index (PMI), and lower trapezius (LT) and serratus anterior (SA) activity in subjects with RSP.
Short-term ECG recordings for heart rate assessment in patients with chronic atrial fibrillation.
Wranicz et al., Łódź, Poland. In Arch Med Sci, Sep 2014
PM, 12 PM-1.00
[Correlation between five RNA markers of rat's skin and PMI at different temperatures].
Chen et al., In Fa Yi Xue Za Zhi, Aug 2014
OBJECTIVE: To explore the correlation between postmortem interval (PMI) and five RNA markers of rat's skin--β-actin, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), 18S ribosomal RNA(18S rRNA), 5S ribosomal RNA (5S rRNA), and microRNA-203 (miR-203), at different temperatures.
Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity.
Contessa et al., New Haven, United States. In Plos One, Dec 2013
To gain insight into the regulatory role of glycosylation enzymes on RTK function, we investigated shRNA and siRNA knockdown of mannose phosphate isomerase (MPI), an enzyme required for mature glycan precursor biosynthesis.
Cenicriviroc blocks HIV entry but does not lead to redistribution of HIV into extracellular space like maraviroc.
Wainberg et al., Montréal, Canada. In J Int Aids Soc, Dec 2013
In vitro: PM-1 cells were infected with CCR5-tropic HIV-1 BaL in the presence or absence of inhibitory concentrations of CVC (20 nM), MVC (50 nM) or controls.
Risk assessment and regulation of molecular farming - a comparison between Europe and US.
Schiemann et al., Norwich, United Kingdom. In Curr Pharm Des, 2012
In this article, the general principles of genetically modified (GM) plant risk assessment and the regulatory framework for contained use and open field production of plant-made pharmaceuticals/plant-made industrials (PMP/PMI) are described.
Statin loading before percutaneous coronary intervention to reduce periprocedural myocardial infarction.
Anderson et al., Tucson, United States. In Cardiol Rev, 2012
Periprocedural myocardial infarction (PMI) is a common complication associated with percutaneous coronary intervention (PCI), occurring in approximately 15% to 20% of patients undergoing the procedure.
Structural studies of vacuolar plasmepsins.
Wlodawer et al., Frederick, United States. In Biochim Biophys Acta, 2012
The genome of P. falciparum encodes 10 PMs (PMI, PMII, PMIV-X and histo-aspartic protease (HAP)), 4 of which (PMI, PMII, PMIV and HAP) reside within the food vacuole, are directly involved in degradation of human hemoglobin, and share 50-79% amino acid sequence identity.
Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts.
Freeze et al., Los Angeles, United States. In J Biol Chem, 2011
Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts
A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.
Carr et al., Cambridge, United States. In Nat Biotechnol, 2011
We developed a pipeline to integrate the proteomic technologies used from the discovery to the verification stages of plasma biomarker identification and applied it to identify early biomarkers of cardiac injury from the blood of patients undergoing a therapeutic, planned myocardial infarction (PMI) for treatment of hypertrophic cardiomyopathy.
Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways.
Royet et al., Marseille, France. In Embo Rep, 2011
study demonstrates that the Drosophila PMI gene and its human orthologue TMEM11 encode mitochondrial inner-membrane proteins that regulate mitochondrial morphogenesis
[Application of nucleic acids and proteins in estimation of postmortem interval].
Chen et al., Shanghai, China. In Fa Yi Xue Za Zhi, 2011
Accurate estimation of postmortem interval (PMI) is one of the most important and difficult issues in forensic medicine.
Ontogeny of D-mannose transport and metabolism in rat small intestine.
Ilundain et al., Sevilla, Spain. In J Membr Biol, 2010
Phosphomannose isomerase activity and mRNA levels increased at 1 month, and the values in the ileum were lower than in jejunum.
[Review on estimation of postmortem interval using FTIR spectroscopy].
Wang et al., Shanghai, China. In Fa Yi Xue Za Zhi, 2010
Estimation of the postmortem interval (PMI) is a practical task in daily forensic casework.
The relative contribution of mannose salvage pathways to glycosylation in PMI-deficient mouse embryonic fibroblast cells.
Nishikawa et al., Tokyo, Japan. In Febs J, 2008
Data conclude that PMI-null cells can salvage mannose from both endogenous and external glycoconjugates via lysosomal and nonlysosomal degradation pathways.
Computational study of human phosphomannose isomerase: Insights from homology modeling and molecular dynamics simulation of enzyme bound substrate.
Sun et al., Beijing, China. In J Mol Graph Model, 2006
The mannose-6-phosphate-enzyme complex is developed and the key residues involved in the ligand binding are determined. Our results suggest a hydride transfer mechanism of alpha-hydrogen between the C1 and C2 positions.
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