Analysis of RNA from Alzheimer's Disease Post-mortem Brain Tissues.
New Orleans, United States. In Mol Neurobiol, Mar 2015
To more completely analyze and understand the neuropathology, altered neuro-inflammatory and innate-immune signaling pathways, and the complex molecular-genetics and epigenetics of AD, it is therefore necessary to rigorously examine short post-mortem interval (PMI) human brain tissues to gain a deeper and more thorough insight into the neuropathological mechanisms that characterize the AD process.
Structural studies of vacuolar plasmepsins.
Frederick, United States. In Biochim Biophys Acta, 2012
The genome of P. falciparum encodes 10 PMs (PMI, PMII, PMIV-X and histo-aspartic protease (HAP)), 4 of which (PMI, PMII, PMIV and HAP) reside within the food vacuole, are directly involved in degradation of human hemoglobin, and share 50-79% amino acid sequence identity.