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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 May 2015.

Mannose phosphate isomerase

PMI, Mannose-6-Phosphate Isomerase, mannose phosphate isomerase, PM-1
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, HAD, CAN, AGE, CD45
Papers on PMI
An extract of artemisia dracunculus L. stimulates insulin secretion from β cells, activates AMPK and suppresses inflammation.
New
Qingxia Wang et al., Rochester, United States. In J Ethnopharmacol, 13 Jun 2015
AIM OF THE STUDY: In this study a defined plant extract from Artemisia dracunculus L. (termed PMI-5011) is used to improve β cells function and maintain β cell number in pancreatic islets as an alternative drug approach for successful treatment of diabetes.
The effect of elapsed time on the cardiac Troponin-T (cTnT) proteolysis in case of death due to burn: A study to evaluate the potential forensic use of cTnT to determine the postmortem interval.
New
Verma et al., Lucknow, India. In Sci Justice, 31 May 2015
BACKGROUND: After the death of an organism, intracellular enzymes cause protein to degrade into smaller fragments as the time passes, if these fragments can be isolated and visualized, and if the fragmentation is proved to be measurable and quantifiable, it can be a good sign of the post-mortem interval (PMI).
Non-enzymatic lipid mediators, neuroprostanes, exert the anti-arrhythmic properties of docosahexaenoic acid.
New
Le Guennec et al., Montpellier, France. In Free Radic Biol Med, 21 May 2015
The aim of this study was to investigate the influence of DHA peroxidation on its potentially anti-arrhythmic properties (AAP) in isolated ventricular cardiomyocytes and in vivo in post-myocardial infarcted (PMI) mice.
Comparison of the post-mortem interval on the effect of vascular responses to the activation of ionotropic and metabotropic receptors.
New
Grześk et al., Bydgoszcz, Poland. In Biomed Rep, Mar 2015
The main aim of the study was to investigate, by means of perfusion pressure in rat tail arteries, the role of Ca(2+) in vascular response to α-1 adrenoceptor activation by phenylephrine (PHE) and Bay K8644 agonist of the L-type calcium channel and caffeine before and after a post-mortem interval (PMI) of 2, 4, 6 and 8 h.
Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury.
New
Carr et al., United States. In Mol Cell Proteomics, Mar 2015
We applied the new workflow to a time series of plasma samples from patients undergoing a therapeutic, planned myocardial infarction (PMI) for hypertrophic cardiomyopathy, a unique human model in which each person serves as their own biologic control.
ABORTED GAMETOPHYTE 1 is required for gametogenesis in Arabidopsis.
New
Zhang et al., Beijing, China. In J Integr Plant Biol, Mar 2015
Our results suggest that AOG1 plays important roles in gametogenesis at the stage prior to pollen mitosis I (PMI) in Arabidopsis, possibly through collaboration with other genes.
Prognostic Significance of Peri-procedural Myocardial Infarction in the Era of High Sensitivity Troponin: A Validation of the Joint ACCF/AHA/ESC/WHF Universal Definition of Type 4a Myocardial Infarction with High Sensitivity Troponin T.
New
Ooi et al., Australia. In Heart Lung Circ, Mar 2015
AIMS: This study aims to validate the joint ACCF/AHA/ESC/WHF Universal Definition of peri-procedural myocardial infarction (PMI) with high sensitivity troponin T (hsTnT).
Analysis of RNA from Alzheimer's Disease Post-mortem Brain Tissues.
New
Lukiw et al., New Orleans, United States. In Mol Neurobiol, Mar 2015
To more completely analyze and understand the neuropathology, altered neuro-inflammatory and innate-immune signaling pathways, and the complex molecular-genetics and epigenetics of AD, it is therefore necessary to rigorously examine short post-mortem interval (PMI) human brain tissues to gain a deeper and more thorough insight into the neuropathological mechanisms that characterize the AD process.
Phosphomannose isomerase affects the key enzymes of glycolysis and sucrose metabolism in transgenic sugarcane overexpressing the manA gene.
New
Chen et al., Nanning, China. In Mol Breed, Dec 2014
In this paper, the influence of phosphomannose isomerase (PMI) overexpression on the key enzymes of both glycolysis and sucrose metabolism was investigated in transgenic sugarcane through the manA gene.
[Detection technologies of microRNA and their prospects for forensic applications].
Review
New
Hou et al., In Fa Yi Xue Za Zhi, Feb 2014
With the advance of the miRNA detection technologies, miRNA has been introduced to forensic science as a potentially novel set of genetic markers of forensic body fluid identification, species identification and PMI estimation.
Cardiac remote ischaemic preconditioning reduces periprocedural myocardial infarction for patients undergoing percutaneous coronary interventions: a meta-analysis of randomised clinical trials.
Review
Gaita et al., Torino, Italy. In Eurointervention, 2013
Periprocedural myocardial infarction (PMI) was the primary endpoint (defined as troponin elevation >3 times upper reference limit) and C-reactive protein (CRP) was a secondary endpoint.
Risk assessment and regulation of molecular farming - a comparison between Europe and US.
Review
Schiemann et al., Norwich, United Kingdom. In Curr Pharm Des, 2012
In this article, the general principles of genetically modified (GM) plant risk assessment and the regulatory framework for contained use and open field production of plant-made pharmaceuticals/plant-made industrials (PMP/PMI) are described.
Statin loading before percutaneous coronary intervention to reduce periprocedural myocardial infarction.
Review
Anderson et al., Tucson, United States. In Cardiol Rev, 2012
Periprocedural myocardial infarction (PMI) is a common complication associated with percutaneous coronary intervention (PCI), occurring in approximately 15% to 20% of patients undergoing the procedure.
Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts.
GeneRIF
Freeze et al., Los Angeles, United States. In J Biol Chem, 2011
Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts
A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.
Impact
Carr et al., Cambridge, United States. In Nat Biotechnol, 2011
We developed a pipeline to integrate the proteomic technologies used from the discovery to the verification stages of plasma biomarker identification and applied it to identify early biomarkers of cardiac injury from the blood of patients undergoing a therapeutic, planned myocardial infarction (PMI) for treatment of hypertrophic cardiomyopathy.
Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways.
GeneRIF
Royet et al., Marseille, France. In Embo Rep, 2011
study demonstrates that the Drosophila PMI gene and its human orthologue TMEM11 encode mitochondrial inner-membrane proteins that regulate mitochondrial morphogenesis
[Application of nucleic acids and proteins in estimation of postmortem interval].
Review
Chen et al., Shanghai, China. In Fa Yi Xue Za Zhi, 2011
Accurate estimation of postmortem interval (PMI) is one of the most important and difficult issues in forensic medicine.
Ontogeny of D-mannose transport and metabolism in rat small intestine.
GeneRIF
Ilundain et al., Sevilla, Spain. In J Membr Biol, 2010
Phosphomannose isomerase activity and mRNA levels increased at 1 month, and the values in the ileum were lower than in jejunum.
The relative contribution of mannose salvage pathways to glycosylation in PMI-deficient mouse embryonic fibroblast cells.
GeneRIF
Nishikawa et al., Tokyo, Japan. In Febs J, 2008
Data conclude that PMI-null cells can salvage mannose from both endogenous and external glycoconjugates via lysosomal and nonlysosomal degradation pathways.
Computational study of human phosphomannose isomerase: Insights from homology modeling and molecular dynamics simulation of enzyme bound substrate.
GeneRIF
Sun et al., Beijing, China. In J Mol Graph Model, 2006
The mannose-6-phosphate-enzyme complex is developed and the key residues involved in the ligand binding are determined. Our results suggest a hydride transfer mechanism of alpha-hydrogen between the C1 and C2 positions.
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