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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 07 Jul 2015.

Mannose phosphate isomerase

PMI, Mannose-6-Phosphate Isomerase, mannose phosphate isomerase, PM-1
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, HAD, CAN, AGE, CD45
Papers on PMI
An extract of Artemisia dracunculus L. stimulates insulin secretion from β cells, activates AMPK and suppresses inflammation.
Qingxia Wang et al., Baton Rouge, United States. In J Ethnopharmacol, 21 Aug 2015
AIM OF THE STUDY: In this study a defined plant extract from A. dracunculus L. (termed PMI-5011) is used to improve beta(β) cells function and maintain β cell number in pancreatic islets as an alternative drug approach for successful treatment of diabetes.
Structural basis of how stress-induced MDMX phosphorylation activates p53.
Lu et al., Baltimore, United States. In Oncogene, 06 Aug 2015
Herein, we report total chemical synthesis, via native chemical ligation, and functional characterization of (24-108)MDMX and its Tyr99-phosphorylated analog with respect to their ability to interact with a panel of p53-derived peptide ligands and PMI, a p53-mimicking but more potent peptide antagonist of MDMX, using FP and surface plasmon resonance techniques.
Thrombogenicity and early vascular healing response in metallic biodegradable polymer-based and fully bioabsorbable drug-eluting stents.
Joner et al., Gaithersburg, United States. In Circ Cardiovasc Interv, 30 Jun 2015
Confocal microscopy was used to detect fluorescently labeled antibody staining directed against CD61/CD42b for the identification of aggregated thrombocytes, CD14/PM-1, and RAM-11 for identification of neutrophils and monocytes/macrophages.
The effect of elapsed time on the cardiac Troponin-T (cTnT) proteolysis in case of death due to burn: A study to evaluate the potential forensic use of cTnT to determine the postmortem interval.
Verma et al., Lucknow, India. In Sci Justice, May 2015
BACKGROUND: After the death of an organism, intracellular enzymes cause protein to degrade into smaller fragments as the time passes, if these fragments can be isolated and visualized, and if the fragmentation is proved to be measurable and quantifiable, it can be a good sign of the post-mortem interval (PMI).
Non-enzymatic lipid mediators, neuroprostanes, exert the anti-arrhythmic properties of docosahexaenoic acid.
Le Guennec et al., Montpellier, France. In Free Radic Biol Med, May 2015
The aim of this study was to investigate the influence of DHA peroxidation on its potentially anti-arrhythmic properties (AAP) in isolated ventricular cardiomyocytes and in vivo in post-myocardial infarcted (PMI) mice.
Comparison of the post-mortem interval on the effect of vascular responses to the activation of ionotropic and metabotropic receptors.
Grześk et al., Bydgoszcz, Poland. In Biomed Rep, Mar 2015
The main aim of the study was to investigate, by means of perfusion pressure in rat tail arteries, the role of Ca(2+) in vascular response to α-1 adrenoceptor activation by phenylephrine (PHE) and Bay K8644 agonist of the L-type calcium channel and caffeine before and after a post-mortem interval (PMI) of 2, 4, 6 and 8 h.
Phosphomannose isomerase affects the key enzymes of glycolysis and sucrose metabolism in transgenic sugarcane overexpressing the manA gene.
Chen et al., Nanning, China. In Mol Breed, Dec 2014
In this paper, the influence of phosphomannose isomerase (PMI) overexpression on the key enzymes of both glycolysis and sucrose metabolism was investigated in transgenic sugarcane through the manA gene.
Determining the Advantages, Costs, and Trade-Offs of a Novel Sodium Channel Mutation in the Copepod Acartia hudsonica to Paralytic Shellfish Toxins (PST).
Dam et al., United States. In Plos One, Dec 2014
All A. hudsonica copepods express both the wild-type and mutant sodium channel isoforms, but in different proportions; some individuals express predominantly mutant (PMI) or wild-type isoforms (PWI), while most individuals express relatively equal amounts of each (EI).
DNA methylation results depend on DNA integrity-role of post mortem interval.
Frieling et al., Hannover, Germany. In Front Genet, Dec 2014
After opening the brain cavity, we kept two consecutive pig skulls at ambient temperature (19-21°C) and removed cortex tissue up to a post mortem interval (PMI) of 120 h.
[Detection technologies of microRNA and their prospects for forensic applications].
Hou et al., In Fa Yi Xue Za Zhi, Feb 2014
With the advance of the miRNA detection technologies, miRNA has been introduced to forensic science as a potentially novel set of genetic markers of forensic body fluid identification, species identification and PMI estimation.
Cardiac remote ischaemic preconditioning reduces periprocedural myocardial infarction for patients undergoing percutaneous coronary interventions: a meta-analysis of randomised clinical trials.
Gaita et al., Torino, Italy. In Eurointervention, 2013
Periprocedural myocardial infarction (PMI) was the primary endpoint (defined as troponin elevation >3 times upper reference limit) and C-reactive protein (CRP) was a secondary endpoint.
Risk assessment and regulation of molecular farming - a comparison between Europe and US.
Schiemann et al., Norwich, United Kingdom. In Curr Pharm Des, 2012
In this article, the general principles of genetically modified (GM) plant risk assessment and the regulatory framework for contained use and open field production of plant-made pharmaceuticals/plant-made industrials (PMP/PMI) are described.
Statin loading before percutaneous coronary intervention to reduce periprocedural myocardial infarction.
Anderson et al., Tucson, United States. In Cardiol Rev, 2012
Periprocedural myocardial infarction (PMI) is a common complication associated with percutaneous coronary intervention (PCI), occurring in approximately 15% to 20% of patients undergoing the procedure.
Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts.
Freeze et al., Los Angeles, United States. In J Biol Chem, 2011
Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts
A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.
Carr et al., Cambridge, United States. In Nat Biotechnol, 2011
We developed a pipeline to integrate the proteomic technologies used from the discovery to the verification stages of plasma biomarker identification and applied it to identify early biomarkers of cardiac injury from the blood of patients undergoing a therapeutic, planned myocardial infarction (PMI) for treatment of hypertrophic cardiomyopathy.
Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways.
Royet et al., Marseille, France. In Embo Rep, 2011
study demonstrates that the Drosophila PMI gene and its human orthologue TMEM11 encode mitochondrial inner-membrane proteins that regulate mitochondrial morphogenesis
[Application of nucleic acids and proteins in estimation of postmortem interval].
Chen et al., Shanghai, China. In Fa Yi Xue Za Zhi, 2011
Accurate estimation of postmortem interval (PMI) is one of the most important and difficult issues in forensic medicine.
Ontogeny of D-mannose transport and metabolism in rat small intestine.
Ilundain et al., Sevilla, Spain. In J Membr Biol, 2010
Phosphomannose isomerase activity and mRNA levels increased at 1 month, and the values in the ileum were lower than in jejunum.
The relative contribution of mannose salvage pathways to glycosylation in PMI-deficient mouse embryonic fibroblast cells.
Nishikawa et al., Tokyo, Japan. In Febs J, 2008
Data conclude that PMI-null cells can salvage mannose from both endogenous and external glycoconjugates via lysosomal and nonlysosomal degradation pathways.
Computational study of human phosphomannose isomerase: Insights from homology modeling and molecular dynamics simulation of enzyme bound substrate.
Sun et al., Beijing, China. In J Mol Graph Model, 2006
The mannose-6-phosphate-enzyme complex is developed and the key residues involved in the ligand binding are determined. Our results suggest a hydride transfer mechanism of alpha-hydrogen between the C1 and C2 positions.
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